Universität zu Köln

Journal Article

Jiao, Huipeng ORCID: 0000-0001-9632-6176, Wachsmuth, Laurens, Wolf, Simone ORCID: 0000-0003-2073-8312, Lohmann, Juliane, Nagata, Masahiro, Kaya, Goeksu Goekberk, Oikonomou, Nikos, Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Rogg, Manuel ORCID: 0000-0002-6658-9159, Diebold, Martin ORCID: 0000-0001-9636-6936, Troeder, Simon E., Zevnik, Branko, Prinz, Marco, Schell, Christoph ORCID: 0000-0001-5344-624X, Young, George R., Kassiotis, George and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2022). ADAR1 averts fatal type I interferon induction by ZBP1. Nature, 607 (7920). S. 776 - 804. BERLIN: NATURE PORTFOLIO. ISSN 1476-4687

Jiao, Huipeng ORCID: 0000-0001-9632-6176 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2022). Inducing Z-DNA overcomes immune checkpoint blockade resistance. Cell Res., 32 (10). S. 871 - 873. LONDON: SPRINGERNATURE. ISSN 1748-7838

Kopelyanskiy, Dmitry ORCID: 0000-0003-2196-2527, Desponds, Chantal, Prevel, Florence, Rossi, Matteo, Migliorini, Romain, Snaka, Tiia, Eren, Remzi Onur ORCID: 0000-0003-2795-0156, Claudinot, Stephanie, Lye, Lon-Fye, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Beverley, Stephen M. and Fasel, Nicolas (2022). Leishmania guyanensis suppressed inducible nitric oxide synthase provoked by its viral endosymbiont. Front. Cell. Infect. Microbiol., 12. LAUSANNE: FRONTIERS MEDIA SA. ISSN 2235-2988

Imai, Takashi, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Polykratis, Apostolos (2022). Smooth muscle cell specific NEMO deficiency inhibits atherosclerosis in ApoE(-/-) mice. Sci Rep, 12 (1). BERLIN: NATURE PORTFOLIO. ISSN 2045-2322

Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Schneider, Farina, Schorn, Fabian, Oikonomou, Nikos, Straub, Beate Katharina, Werner, Sabine, Rosenstiel, Philip ORCID: 0000-0002-9692-8828 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2022). p62 Promotes Survival and Hepatocarcinogenesis in Mice with Liver-Specific NEMO Ablation. Cancers, 14 (10). BASEL: MDPI. ISSN 2072-6694

Oikonomou, Nikos, Schuijs, Martjin J., Chatzigiagkos, Antonis, Androulidaki, Ariadne, Aidinis, Vassilis, Hammad, Hamida, Lambrecht, Bart N. and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2021). Airway epithelial cell necroptosis contributes to asthma exacerbation in a mouse model of house dust mite-induced allergic inflammation. Mucosal Immunol., 14 (5). S. 1160 - 1172. LONDON: SPRINGERNATURE. ISSN 1935-3456

Theobald, Sebastian J., Graeb, Jessica, Fritsch, Melanie, Suarez, Isabelle, Eisfeld, Hannah S., Winter, Sandra, Koch, Maximilian, Hoelscher, Christoph, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Kashkar, Hamid and Rybniker, Jan (2021). Gasdermin D mediates host cell death but not interleukin-1 beta secretion in Mycobacterium tuberculosis-infected macrophages. Cell Death Discov., 7 (1). LONDON: SPRINGERNATURE. ISSN 2058-7716

Hausmann, Annika ORCID: 0000-0001-8852-3444, Felmy, Boas, Kunz, Leo, Kroon, Sanne, Berthold, Dorothee Lisa, Ganz, Giverny, Sandu, Ioana, Nakamura, Toshihiro ORCID: 0000-0001-5051-4323, Zangger, Nathan Sebastien, Zhang, Yang, Dolowschiak, Tamas, Fattinger, Stefan Alexander, Furter, Markus, Mueller-Hauser, Anna Angelika, Barthel, Manja, Vlantis, Katerina, Wachsmuth, Laurens ORCID: 0000-0003-1701-9384, Kisielow, Jan ORCID: 0000-0002-4482-5202, Tortola, Luigi ORCID: 0000-0002-8480-2080, Heide, Danijela, Heikenwaelder, Mathias, Oxenius, Annette, Kopf, Manfred, Schroeder, Timm, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Sellin, Mikael Erik and Hardt, Wolf-Dietrich (2021). Intercrypt sentinel macrophages tune antibacterial NF-kappa B responses in gut epithelial cells via TNF. J. Exp. Med., 218 (11). NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-9538

Kumari, Snehlata ORCID: 0000-0002-4971-3162, Preukschat, Daniela, Schuenke, Hannah, Basic, Marijana, Bleich, Andre, Klein, Ulf and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2021). NF-kappa B inhibition in keratinocytes causes RIPK1-mediated necroptosis and skin inflammation. Life Sci. Alliance, 4 (6). COLD SPRING HARBOR: LIFE SCIENCE ALLIANCE LLC. ISSN 2575-1077

Wenzel, Jan ORCID: 0000-0001-6313-2439, Lampe, Josephine, Mueller-Fielitz, Helge, Schuster, Raphael, Zille, Marietta ORCID: 0000-0002-0609-8956, Mueller, Kristin, Krohn, Markus ORCID: 0000-0002-5345-9048, Koerbelin, Jakob, Zhang, Linlin, Ozorhan, Umit, Neve, Vanessa, Wagner, Julian U. G., Bojkova, Denisa, Shumliakivska, Mariana, Jiang, Yun ORCID: 0000-0002-2886-7373, Faehnrich, Anke, Ott, Fabian, Sencio, Valentin, Robil, Cyril, Pfefferle, Susanne, Sauve, Florent, Coelho, Caio Fernando Ferreira, Franz, Jonas ORCID: 0000-0001-7523-6622, Spiecker, Frauke, Lembrich, Beate, Binder, Sonja, Feller, Nina, Koenig, Peter, Busch, Hauke, Collin, Ludovic, Villasenor, Roberto, Joehren, Olaf, Altmeppen, Hermann C., Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Dimmeler, Stefanie, Cinatl, Jindrich, Pueschel, Klaus, Zelic, Matija, Ofengeim, Dimitry, Stadelmann, Christine, Trottein, Francois, Nogueiras, Ruben, Hilgenfeld, Rolf, Glatzel, Markus, Prevot, Vincent and Schwaninger, Markus (2021). The SARS-CoV-2 main protease M-pro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells. Nat. Neurosci., 24 (11). S. 1522 - 1534. BERLIN: NATURE PORTFOLIO. ISSN 1546-1726

Schwarzer, Robin, Jiao, Huipeng, Wachsmuth, Laurens, Tresch, Achim and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2020). FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells. Immunity, 52.

Laurien, Lucie, Nagata, Masahiro, Schuenke, Hannah, Delanghe, Tom, Wiederstein, Janica L., Kumari, Snehlata, Schwarzer, Robin, Corona, Teresa, Krueger, Marcus ORCID: 0000-0003-2008-4582, Bertrand, Mathieu J. M., Kondylis, Vangelis and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2020). Autophosphorylation at serine 166 regulates RIP kinase 1-mediated cell death and inflammation. Nat. Commun., 11 (1). LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Pedragosa, Jordi, Miro-Mur, Francesc, Otxoa-de-Amezaga, Amaia, Justicia, Carles, Ruiz-Jaen, Francisca, Ponsaerts, Peter ORCID: 0000-0002-1892-6499, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Planas, Anna M. (2020). CCR2 deficiency in monocytes impairs angiogenesis and functional recovery after ischemic stroke in mice. J. Cereb. Blood Flow Metab., 40 (1_SUPPL). S. S98 - 19. THOUSAND OAKS: SAGE PUBLICATIONS INC. ISSN 1559-7016

Schwarzer, Robin, Jiao, Huipeng ORCID: 0000-0001-9632-6176, Wachsmuth, Laurens ORCID: 0000-0003-1701-9384, Tresch, Achim ORCID: 0000-0002-4146-6371 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2020). FADD and Caspase-8 Regulate Gut Homeostasis and Inflammation by Controlling MLKL- and GSDMD-Mediated Death of Intestinal Epithelial Cells. Immunity, 52 (6). 978-993.e6. Cell Press. ISSN 1074-7613

Schiffmann, L. M., Werthenbach, J. P., Heintges-Kleinhofer, F., Seeger, J. M., Fritsch, M., Guenther, S. D., Willenborg, S., Brodesser, S., Lucas, C., Juengst, C., Albert, M. C., Schorn, F., Witt, A., Moraes, C. T., Bruns, C. J., Pasparakis, M. ORCID: 0000-0002-9870-0966, Kroenke, M., Eming, S. A., Coutelle, O. and Kashkar, H. (2020). Mitochondrial respiration controls neoangiogenesis during wound healing and tumour growth. Nat. Commun., 11 (1). LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Lalaoui, Najoua ORCID: 0000-0002-0165-3324, Boyden, Steven E., Oda, Hirotsugu, Wood, Geryl M., Stone, Deborah L., Chau, Diep, Liu, Lin, Stoffels, Monique, Kratina, Tobias, Lawlor, Kate E., Zaal, Kristien J. M., Hoffmann, Patrycja M., Etemadi, Nima, Shield-Artin, Kristy, Biben, Christine, Tsai, Wanxia Li, Blake, Mary D., Kuehn, Hye Sun, Yang, Dan, Anderton, Holly ORCID: 0000-0003-3913-9686, Silke, Natasha, Wachsmuth, Laurens, Zheng, Lixin, Moura, Natalia Sampaio, Beck, David B., Gutierrez-Cruz, Gustavo, Ombrello, Amanda K., Pinto-Patarroyo, Gineth P., Kueh, Andrew J., Herold, Marco J., Hall, Cathrine, Wang, Hongying, Chae, Jae Jin, Dmitrieva, Natalia I., McKenzie, Mark, Light, Amanda, Barham, Beverly K., Jones, Anne, Romeo, Tina M., Zhou, Qing, Aksentijevich, Ivona, Mullikin, James C., Gross, Andrew J., Shum, Anthony K., Hawkins, Edwin D., Masters, Seth L., Lenardo, Michael J., Boehm, Manfred, Rosenzweig, Sergio D., Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Voss, Anne K., Gadina, Massimo, Kastner, Daniel L. and Silke, John (2020). Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease. Nature, 577 (7788). S. 103 - 123. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Verboom, Lien, Martens, Arne, Priem, Dario ORCID: 0000-0002-2527-1101, Hoste, Esther ORCID: 0000-0002-3181-431X, Sze, Mozes, Vikkula, Hanna, Van Hove, Lisette, Voet, Sofie, Roels, Jana, Maelfait, Jonathan ORCID: 0000-0002-1476-0583, Bongiovanni, Laura, de Bruin, Alain, Scott, Charlotte L., Saeys, Yvan ORCID: 0000-0002-0415-1506, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Bertrand, Mathieu J. M. and van Loo, Geert (2020). OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis. Cell Reports, 30 (7). S. 2237 - 2248. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Wong, Jerry, Garcia-Carbonell, Ricard, Zelic, Matija, Ho, Samuel B., Boland, Brigid S., Yao, Shih-Jing, Desai, Shalin A., Das, Soumita, Planell, Nuria, Harris, Philip A., Font-Burgada, Joan, Taniguchi, Koji, Bertin, John, Salas, Azucena, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Gough, Pete J., Kelliher, Michelle, Karin, Michael and Guma, Monica (2020). RIPK1 Mediates TNF-Induced Intestinal Crypt Apoptosis During Chronic NF-kappa B Activation. Cell. Mol. Gastroenterol. Hepatol., 9 (2). S. 295 - 313. SAN DIEGO: ELSEVIER INC. ISSN 2352-345X

Naito, Masanori Gomi, Xu, Daichao, Amin, Palak ORCID: 0000-0001-5617-8703, Lee, Jinwoo, Wang, Huibing, Li, Wanjin, Kelliher, Michelle, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Yuan, Junying ORCID: 0000-0003-2405-6036 (2020). Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke. Proc. Natl. Acad. Sci. U. S. A., 117 (9). S. 4959 - 4971. WASHINGTON: NATL ACAD SCIENCES. ISSN 0027-8424

Jiao, Huipeng, Wachsmuth, Laurens, Kumari, Snehlata, Schwarzer, Robin, Lin, Juan, Eren, Remzi Onur, Fisher, Amanda, Lane, Rebecca, Young, George R., Kassiotis, George, Kaiser, William J. and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2020). Z-nucleic-acid sensing triggers ZBP1-dependent necroptosis and inflammation. Nature, 580 (7803). S. 391 - 410. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Priem, Dario ORCID: 0000-0002-2527-1101, Devos, Michael ORCID: 0000-0001-9522-6026, Druwe, Sarah, Martens, Arne, Slowicka, Karolina, Ting, Adrian T., Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Declerq, Wim, Vandenabeele, Peter, van Loo, Geert and Bertrand, Mathieu J. M. (2019). A20 protects cells from TNF-induced apoptosis through linear ubiquitin-dependent and -independent mechanisms. Cell Death Dis., 10. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-4889

Fritsch, Melanie, Gunther, Saskia D., Schwarzer, Robin, Albert, Marie-Christine, Schorn, Fabian, Werthenbach, J. Paul, Schiffmann, Lars M., Stair, Neil, Stocks, Hannah ORCID: 0000-0002-4129-5138, Seeger, Jens M., Lamkanfi, Mohamed, Kroenke, Martin, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kashkar, Hamid (2019). Caspase-8 is the molecular switch for apoptosis, necroptosis and pyroptosis. Nature, 575 (7784). S. 683 - 700. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Graeb, Jessica, Suarez, Isabelle, van Gumpel, Edeltraud, Winter, Sandra, Schreiber, Fynn, Esser, Anna, Hoelscher, Christoph, Fritsch, Melanie, Herb, Marc ORCID: 0000-0002-7533-0288, Schramm, Michael, Wachsmuth, Laurens, Pallasch, Christian, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Kashkar, Hamid and Rybniker, Jan (2019). Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating mitochondrial membrane permeability transition. Nat. Commun., 10. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Koliaraki, Vasiliki ORCID: 0000-0003-1694-6987, Chalkidi, Niki, Henriques, Ana, Tzaferis, Christos, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Waisman, Ari, Muller, Werner ORCID: 0000-0002-1297-9725, Hackam, David J., Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kollias, George (2019). Innate Sensing through Mesenchymal TLR4/MyD88 Signals Promotes Spontaneous Intestinal Tumorigenesis. Cell Reports, 26 (3). S. 536 - 550. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

MacVicar, Thomas, Ohba, Yohsuke, Nolte, Hendrik, Mayer, Fiona Carola, Tatsuta, Takashi, Sprenger, Hans-Georg, Lindner, Barbara, Zhao, Yue, Li, Jiahui, Bruns, Christiane, Krueger, Marcus, Habich, Markus, Riemer, Jan, Schwarzer, Robin, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Henschke, Sinika, Bruening, Jens C., Zamboni, Nicola ORCID: 0000-0003-1271-1021 and Langer, Thomas (2019). Lipid signalling drives proteolytic rewiring of mitochondria by YME1L. Nature, 575 (7782). S. 361 - 386. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Kondylis, Vangelis ORCID: 0000-0002-6970-8731 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2019). RIP Kinases in Liver Cell Death, Inflammation and Cancer. Trends Mol. Med, 25 (1). S. 47 - 64. OXFORD: ELSEVIER SCI LTD. ISSN 1471-499X

Liccardi, Gianmaria, Garcia, Laura Ramos, Tenev, Tencho, Annibaldi, Alessandro ORCID: 0000-0002-0346-4340, Legrand, Arnaud J., Robertson, David, Feltham, Rebecca, Anderton, Holly ORCID: 0000-0003-3913-9686, Darding, Maurice, Peltzer, Nieves ORCID: 0000-0002-4134-5852, Dannappel, Marius, Schunke, Hannah, Fava, Luca L., Haschka, Manuel D., Glatter, Timo, Nesvizhskii, Alexey, Schmidt, Alexander, Harris, Philip A., Bertin, John, Gough, Peter J., Villunger, Andreas, Silke, John ORCID: 0000-0002-7611-5774, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Bianchi, Katiuscia and Meier, Pascal ORCID: 0000-0003-2760-6523 (2019). RIPK1 and Caspase-8 Ensure Chromosome Stability Independently of Their Role in Cell Death and Inflammation. Mol. Cell, 73 (3). S. 413 - 436. CAMBRIDGE: CELL PRESS. ISSN 1097-4164

Krishna-Subramanian, Santosh, Singer, Stephan, Armaka, Marietta, Banales, Jesus M., Holzer, Kerstin, Schirmacher, Peter, Walczak, Henning ORCID: 0000-0002-6312-4591, Kollias, George, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kondylis, Vangelis ORCID: 0000-0002-6970-8731 (2019). RIPK1 and death receptor signaling drive biliary damage and early liver tumorigenesis in mice with chronic hepatobiliary injury. Cell Death Differ., 26 (12). S. 2710 - 2727. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5403

Eftychi, Christina, Schwarzer, Robin, Vlantis, Katerina, Wachsmuth, Laurens, Basic, Marijana, Wagle, Prerana, Neurath, Markus F., Becker, Christoph, Bleich, Andre and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2019). Temporally Distinct Functions of the Cytokines IL-12 and IL-23 Drive Chronic Colon Inflammation in Response to Intestinal Barrier Impairment. Immunity, 51 (2). S. 367 - 385. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

Aden, Konrad ORCID: 0000-0003-3482-7316, Tran, Florian, Ito, Go, Sheibani-Tezerji, Raheleh, Lipinski, Simone, Kuiper, Jan W., Tschurtschenthaler, Markus ORCID: 0000-0002-0060-4790, Saveljeva, Svetlana, Bhattacharyya, Joya ORCID: 0000-0003-1745-4167, Haesler, Robert, Bartsch, Kareen, Luzius, Anne, Jentzsch, Marlene, Falk-Paulsen, Maren, Stengel, Stephanie T., Welz, Lina, Schwarzer, Robin, Rabe, Bjoern, Barchet, Winfried ORCID: 0000-0002-6745-6606, Krautwald, Stefan ORCID: 0000-0001-7768-2132, Hartmann, Gunther ORCID: 0000-0003-1021-2018, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Blumberg, Richard S., Schreiber, Stefan, Kaser, Arthur and Rosenstiel, Philip ORCID: 0000-0002-9692-8828 (2018). ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STING. J. Exp. Med., 215 (11). S. 2868 - 2887. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-9538

Torgovnick, Alessandro, Heger, Jan Michel, Liaki, Vasiliki, Isensee, Joerg ORCID: 0000-0002-3390-0051, Schmitt, Anna, Knittel, Gero, Riabinska, Arina, Beleggia, Filippo ORCID: 0000-0003-0234-7094, Laurien, Lucie, Leeser, Uschi, Juengst, Christian, Siedek, Florian, Vogel, Wenzel, Kluemper, Niklas, Nolte, Hendrik, Wittersheim, Maike, Tharun, Lars, Castiglione, Roberta ORCID: 0000-0002-9828-4405, Krueger, Marcus, Schauss, Astrid, Perner, Sven, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Buettner, Reinhard, Persigehl, Thorsten, Hucho, Tim, Herter-Sprie, Grit Sophie, Schumacher, Bjoern and Reinhardt, Hans Christian (2018). The Cdkn1a(SuPER) Mouse as a Tool to Study p53-Mediated Tumor Suppression. Cell Reports, 25 (4). S. 1027 - 1046. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Kumari, S., Lin, J., Kim, S., Van, T-M, Wachsmuth, L., Polykratis, A. and Pasparakis, M. ORCID: 0000-0002-9870-0966 (2018). Cell Death and the Regulatory Network of DAMPs in Skin Inflammation. J. Dtsch. Dermatol. Ges., 16. S. 45 - 46. HOBOKEN: WILEY. ISSN 1610-0387

Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kelliher, Michelle (2018). Connecting immune deficiency and inflammation. Science, 361 (6404). S. 756 - 758. WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1095-9203

O'Donnell, Joanne A., Lehman, Jesse, Roderick, Justine E., Martinez-Marin, Dalia ORCID: 0000-0002-5476-4618, Zelic, Matija, Doran, Ciara, Hermance, Nicole, Lyle, Stephen, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Fitzgerald, Katherine A., Marshak-Rothstein, Ann and Kelliher, Michelle A. (2018). Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity. J. Immunol., 200 (2). S. 737 - 749. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

Androulidaki, Ariadne, Wachsmuth, Laurens, Polykratis, Apostolos ORCID: 0000-0001-6720-3302 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2018). Differential role of MyD88 and TRIF signaling in myeloid cells in the pathogenesis of autoimmune diabetes. PLoS One, 13 (3). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Vreka, Malamati, Lilis, Ioannis, Papageorgopoulou, Maria, Giotopoulou, Georgia A., Lianou, Marina, Giopanou, Ioanna ORCID: 0000-0003-4393-7517, Kanellakis, Nikolaos I., Spella, Magda, Agalioti, Theodora ORCID: 0000-0002-5898-2751, Armenis, Vasileios, Goldmann, Torsten ORCID: 0000-0002-1621-560X, Marwitz, Sebastian ORCID: 0000-0003-4920-5552, Yull, Fiona E., Blackwell, Timothy S., Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Marazioti, Antonia and Stathopoulos, Georgios T. (2018). I kappa B Kinase alpha Is Required for Development and Progression of KRAS-Mutant Lung Adenocarcinoma. Cancer Res., 78 (11). S. 2939 - 2952. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1538-7445

Kumari, S., Van, T. and Pasparakis, M. ORCID: 0000-0002-9870-0966 (2018). IKK/NF-kB signaling in keratinocytes controls TNF-dependent necroptosis- and apoptosis-mediated skin inflammation. J. Invest. Dermatol., 138 (5). S. S165 - 1. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

Koliaraki, V., Henriques, A., Chalkidi, N., Polykratis, A., Pasparakis, M. ORCID: 0000-0002-9870-0966 and Kollias, G. (2018). Innate mesenchymal MyD88 signals promote spontaneous intestinal tumorigenesis. J. Crohns Colitis, 12. S. S87 - 1. OXFORD: OXFORD UNIV PRESS. ISSN 1876-4479

Taraborrelli, Lucia, Peltzer, Nieves ORCID: 0000-0002-4134-5852, Montinaro, Antonella, Kupka, Sebastian, Rieser, Eva, Hartwig, Torsten, Sarr, Aida, Darding, Maurice, Draber, Peter ORCID: 0000-0001-8658-4614, Haas, Tobias L., Akarca, Ayse, Marafioti, Teresa ORCID: 0000-0003-1223-6275, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Bertin, John, Gough, Peter J., Bouillet, Philippe ORCID: 0000-0002-9012-6058, Strasser, Andreas ORCID: 0000-0002-5020-4891, Leverkus, Martin, Silke, John ORCID: 0000-0002-7611-5774 and Walczak, Henning ORCID: 0000-0002-6312-4591 (2018). LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L. Nat. Commun., 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Galluzzi, Lorenzo, Vitale, Ilio, Aaronson, Stuart A., Abrams, John M., Adam, Dieter ORCID: 0000-0002-5668-5032, Agostinis, Patrizia ORCID: 0000-0003-1314-2115, Alnemri, Emad S., Altucci, Lucia, Amelio, Ivano, Andrews, David W., Annicchiarico-Petruzzelli, Margherita ORCID: 0000-0002-4717-4740, Antonov, Alexey V., Arama, Eli, Baehrecke, Eric H., Barlev, Nickolai A., Bazan, Nicolas G., Bernassola, Francesca, Bertrand, Mathieu J. M., Bianchi, Katiuscia, Blagosklonny, Mikhail V., Blomgren, Klas, Borner, Christoph, Boya, Patricia ORCID: 0000-0003-3045-951X, Brenner, Catherine, Campanella, Michelangelo, Candi, Eleonora, Carmona-Gutierrez, Didac ORCID: 0000-0001-7548-7771, Cecconi, Francesco, Chan, Francis K. -M., Chandel, Navdeep S., Cheng, Emily H., Chipuk, Jerry E., Cidlowski, John A., Ciechanover, Aaron, Cohen, Gerald M., Conrad, Marcus ORCID: 0000-0003-1140-5612, Cubillos-Ruiz, Juan R., Czabotar, Peter E., D'Angiolella, Vincenzo, Dawson, Ted M., Dawson, Valina L., De laurenzi, Vincenzo, De Maria, Ruggero ORCID: 0000-0003-2255-0583, Debatin, Klaus-Michael ORCID: 0000-0002-8397-1886, DeBerardinis, Ralph J., Deshmukh, Mohanish, Di Daniele, Nicola, Di Virgilio, Francesco ORCID: 0000-0003-3566-1362, Dixit, Vishva M., Dixon, Scott J., Duckett, Colin S., Dynlacht, Brian D., El-Deiry, Wafik S., Elrod, John W., Fimia, Gian Maria ORCID: 0000-0003-4438-3325, Fulda, Simone ORCID: 0000-0002-0459-6417, Garcia-Saez, Ana J., Garg, Abhishek D., Garrido, Carmen, Gavathiotis, Evripidis ORCID: 0000-0001-6319-8331, Golstein, Pierre ORCID: 0000-0003-1750-3483, Gottlieb, Eyal ORCID: 0000-0002-9770-0956, Green, Douglas R., Greene, Lloyd A., Gronemeyer, Hinrich ORCID: 0000-0001-9454-2449, Gross, Atan, Hajnoczky, Gyorgy, Hardwick, J. Marie, Harris, Isaac S., Hengartner, Michael O., Hetz, Claudio, Ichijo, Hidenori, Jaattela, Marja ORCID: 0000-0001-5950-7111, Joseph, Bertrand, Jost, Philipp J. ORCID: 0000-0003-2454-0362, Juin, Philippe P., Kaiser, William J., Karin, Michael, Kaufmann, Thomas ORCID: 0000-0001-9906-874X, Kepp, Oliver ORCID: 0000-0002-6081-9558, Kimchi, Adi, Kitsis, Richard N., Klionsky, Daniel J., Knight, Richard A., Kumar, Sharad ORCID: 0000-0001-7126-9814, Lee, Sam W., Lemasters, John J., Levine, Beth, Linkermann, Andreas ORCID: 0000-0001-6287-9725, Lipton, Stuart A., Lockshin, Richard A., Lopez-Otin, Carlos ORCID: 0000-0001-6964-1904, Lowe, Scott W., Luedde, Tom, Lugli, Enrico, MacFarlane, Marion, Madeo, Frank, Malewicz, Michal, Malorni, Walter, Manic, Gwenola ORCID: 0000-0003-3759-8029, Marine, Jean-Christophe ORCID: 0000-0003-2433-9837, Martin, Seamus J., Martinou, Jean-Claude, Medema, Jan Paul, Mehlen, Patrick, Meier, Pascal ORCID: 0000-0003-2760-6523, Melino, Sonia, Miao, Edward A., Molkentin, Jeffery D., Moll, Ute M., Munoz-Pinedo, Cristina ORCID: 0000-0002-9120-664X, Nagata, Shigekazu ORCID: 0000-0001-9758-8426, Nunez, Gabriel, Oberst, Andrew, Oren, Moshe, Overholtzer, Michael, Pagano, Michele, Panaretakis, Theocharis, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Penninger, Josef M., Pereira, David M. ORCID: 0000-0003-0384-7592, Pervaiz, Shazib, Peter, Marcus E., Piacentini, Mauro ORCID: 0000-0003-2919-1296, Pinton, Paolo, Prehn, Jochen H. M., Puthalakath, Hamsa ORCID: 0000-0001-5178-1175, Rabinovich, Gabriel A., Rehm, Markus ORCID: 0000-0001-6149-9261, Rizzuto, Rosario, Rodrigues, Cecilia M. P., Rubinsztein, David C., Rudel, Thomas, Ryan, Kevin M., Sayan, Emre, Scorrano, Luca ORCID: 0000-0002-8515-8928, Shao, Feng, Shi, Yufang ORCID: 0000-0001-8964-319X, Silke, John ORCID: 0000-0002-7611-5774, Simon, Hans-Uwe ORCID: 0000-0002-9404-7736, Sistigu, Antonella, Stockwell, Brent R., Strasser, Andreas ORCID: 0000-0002-5020-4891, Szabadkai, Gyorgy, Tait, Stephen W. G., Tang, Daolin, Tavernarakis, Nektarios ORCID: 0000-0002-5253-1466, Thorburn, Andrew, Tsujimoto, Yoshihide, Turk, Boris ORCID: 0000-0002-9007-5764, Vanden Berghe, Tom, Vandenabeele, Peter ORCID: 0000-0002-6669-8822, Heiden, Matthew G. Vander, Villunger, Andreas, Virgin, Herbert W., Vousden, Karen H., Vucic, Domagoj, Wagner, Erwin F., Walczak, Henning ORCID: 0000-0002-6312-4591, Wallach, David, Wang, Ying, Wells, James A., Wood, Will, Yuan, Junying, Zakeri, Zahra, Zhivotovsky, Boris ORCID: 0000-0002-2238-3482, Zitvogel, Laurence, Melino, Gerry and Kroemer, Guido (2018). Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. Cell Death Differ., 25 (3). S. 486 - 542. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5403

D'Cruz, Akshay A., Speir, Mary, Bliss-Moreau, Meghan, Dietrich, Sylvia, Chen, Alyce A., Gavillet, Mathilde, Lawlor, Kate E., Vince, James E., Kelliher, Michelle, Hakem, Razq, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Williams, David A., Ericsson, Maria and Croker, Ben A. (2018). Padi4 Regulates NET Formation and Inflammatory Cell Death Downstream of Mlkl. Blood, 132. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Zelic, Matija, Roderick, Justine E., O'Donnell, Joanne A., Lehman, Jesse, Lim, Sung Eun, Janardhan, Harish P., Trivedi, Chinmay M., Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kelliher, Michelle A. (2018). RIP kinase 1-dependent endothelial necroptosis underlies systemic inflammatory response syndrome. J. Clin. Invest., 128 (5). S. 2064 - 2076. ANN ARBOR: AMER SOC CLINICAL INVESTIGATION INC. ISSN 1558-8238

Armaka, Marietta, Ospelt, Caroline ORCID: 0000-0002-9151-4650, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kollias, George (2018). The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts. Nat. Commun., 9. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

D'Cruz, Akshay A., Speir, Mary ORCID: 0000-0003-0384-886X, Bliss-Moreau, Meghan, Dietrich, Sylvia, Wang, Shu, Chen, Alyce A., Gavillet, Mathilde, Al-Obeidi, Arshed, Lawlor, Kate E., Vince, James E., Kelliher, Michelle A., Hakem, Razq, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Williams, David A., Ericsson, Maria and Croker, Ben A. (2018). The pseudokinase MLKL activates PAD4-dependent NET formation in necroptotic neutrophils. Sci. Signal., 11 (546). WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1937-9145

Lebrun, Astrid, Lo Re, Sandra, Chantry, Mathilde, Carerra, Xavier Izquierdo, Uwambayinema, Francine, Ricci, Doriana, Devosse, Raynal, Ibouraadaten, Saloua, Brombin, Lisa, Palmai-Pallag, Mihaly, Yakoub, Yousof, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Lison, Dominique ORCID: 0000-0001-6557-2518 and Huaux, Francois (2017). CCR2(+) monocytic myeloid-derived suppressor cells (M-MDSCs) inhibit collagen degradation and promote lung fibrosis by producing transforming growth factor-1. J. Pathol., 243 (3). S. 320 - 331. HOBOKEN: WILEY. ISSN 1096-9896

Saleh, Danish, Najjar, Malek, Zelic, Matija, Shah, Saumil, Nogusa, Shoko, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Paczosa, Michelle K., Gough, Peter J., Bertin, John, Whalen, Michael, Fitzgerald, Katherine A., Slavov, Nikolai ORCID: 0000-0003-2035-1820, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Balachandran, Siddharth, Kelliher, Michelle, Mecsas, Joan and Degterev, Alexei (2017). Kinase Activities of RIPK1 and RIPK3 Can Direct IFN-beta Synthesis Induced by Lipopolysaccharide. J. Immunol., 198 (11). S. 4435 - 4448. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

Van, Trieu-My, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Straub, Beate Katharina, Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Papadopoulou, Nikoletta and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2017). Kinase-independent functions of RIPK1 regulate hepatocyte survival and liver carcinogenesis. J. Clin. Invest., 127 (7). S. 2662 - 2678. ANN ARBOR: AMER SOC CLINICAL INVESTIGATION INC. ISSN 1558-8238

Jaco, Isabel, Annibaldi, Alessandro ORCID: 0000-0002-0346-4340, Lalaoui, Najoua ORCID: 0000-0002-0165-3324, Wilson, Rebecca, Tenev, Tencho, Laurien, Lucie, Kim, Chun ORCID: 0000-0001-9497-708X, Jamal, Kunzah, John, Sidonie Wicky, Liccardi, Gianmaria, Chau, Diep, Murphy, James M., Brumatti, Gabriela, Feltham, Rebecca, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Silke, John ORCID: 0000-0002-7611-5774 and Meier, Pascal ORCID: 0000-0003-2760-6523 (2017). MK2 Phosphorylates RIPK1 to Prevent TNF-Induced Cell Death. Mol. Cell, 66 (5). S. 698 - 716. CAMBRIDGE: CELL PRESS. ISSN 1097-4164

Wachsmuth, E., Awazawa, M., Aghdam, S., Tellkamp, F., Pasparakis, M. ORCID: 0000-0002-9870-0966, Bruening, J. and Niessen, C. M. (2017). Metabolic and stress kinase signaling control skin barrier function: Implications for diabetic skin complications. J. Invest. Dermatol., 137 (10). S. S207 - 1. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Kumari, Snehlata, Vlantis, Katerina and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2017). The interplay of IKK, NF-kappa B and RIPK1 signaling in the regulation of cell death, tissue homeostasis and inflammation. Immunol. Rev., 277 (1). S. 113 - 128. HOBOKEN: WILEY. ISSN 1600-065X

Knittel, G., Liedgens, P., Korovkina, D., Seeger, J. M., Al-Baldawi, Y., Vlantis, K., Fritz, C., Schaefer, S. C., Klatt, A., Scheel, A., Al-Maarri, M., Bezhanova, S., Montesinos-Rongen, M., Wolz, O. O., Reimann, M., Lohneis, P., Weber, A. N., Wunderlich, F. T., Pasparakis, M. ORCID: 0000-0002-9870-0966, Buettner, R., Persigehl, T., Schmitt, C. A., Odenthal, M., Frenzel, L. P., Kashkar, H. and Reinhardt, H. C. (2016). B CELL-SPECIFIC CONDITIONAL EXPRESSION OF MYD88P.L252P LEADS TO THE DEVELOPMENT OF DIFFUSE LARGE B CELL LYMPHOMA IN MICE. Haematologica, 101. S. 179 - 181. PAVIA: FERRATA STORTI FOUNDATION. ISSN 0390-6078

Knittel, G., Liedgens, P., Korovkina, D., Seeger, J. M., Al-Baldawi, Y., Al-Maarri, M., Fritz, C., Vlantis, K., Bezhanova, S., Scheel, A. H., Wolz, O. -O., Reimann, M., Moeller, P., Lopez, C., Staudt, L. M., Ortmann, M., Pasparakis, M. ORCID: 0000-0002-9870-0966, Siebert, R., Schmitt, C. A., Klatt, A. R., Wunderlich, F. T., Schaefer, S. C., Persigehl, T., Montesinos-Rongen, M., Odenthal, M., Buettner, R., Frenzel, L. P., Kashkar, H. and Reinhardt, H. C. (2016). B cell-specific conditional expression of Myd88 p.L252P leads to the development of diffuse large B cell lymphoma in mice. Oncol. Res. Treat., 39. S. 218 - 220. BASEL: KARGER. ISSN 2296-5262

Knittel, Gero, Liedgens, Paul, Korovkina, Darya, Seeger, Jens M., Al-Baldawi, Yussor, Al-Maarri, Mona, Fritz, Christian, Vlantis, Katerina, Bezhanova, Svetlana ORCID: 0000-0001-7336-9210, Scheel, Andreas H., Wolz, Olaf-Oliver, Reimann, Maurice, Moeller, Peter, Lopez, Cristina ORCID: 0000-0001-6644-1659, Schlesner, Matthias ORCID: 0000-0002-5896-4086, Lohneis, Philipp, Weber, Alexander N. R., Truemper, Lorenz, Staudt, Louis M., Ortmann, Monika, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Siebert, Reiner, Schmitt, Clemens A., Klatt, Andreas R., Wunderlich, F. Thomas, Schaefer, Stephan C., Persigehl, Thorsten, Montesinos-Rongen, Manuel, Odenthal, Margarete, Buettner, Reinhard, Frenzel, Lukas P., Kashkar, Hamid and Reinhardt, H. Christian (2016). B-cell-specific conditional expression of Myd88(p.L252P) leads to the development of diffuse large B-cell lymphoma in mice. Blood, 127 (22). S. 2732 - 2742. WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Wroblewski, R., Armaka, M., Kondylis, V., Pasparakis, M. ORCID: 0000-0002-9870-0966, Lohse, A. W., zur Wiesch, J. S., Kollias, G. and Ehlken, H. (2016). DISTINCT CELL-SPECIFIC TNFR1-SIGNALING DETERMINES LIVER DAMAGE IN EXPERIMENTAL HEPATITIS. J. Hepatol., 64. S. S521 - 2. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1600-0641

Wachsmuth, E., Aghdam, S., Awazawa, M., Guenschmann, C., Pasparakis, M. ORCID: 0000-0002-9870-0966, Bruening, J. and Niessen, C. M. (2016). Epidermal barrier dysfunction upon loss of Insulin/IGF-1R signaling is compensated by p38 alpha Map kinase stress signaling. J. Invest. Dermatol., 136 (9). S. S180 - 1. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

O'Donnell, Joanne, Roderick, Justine E., Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kelliher, Michelle (2016). IFN gamma-Induced Necroptosis Contributes to Hematopoietic Stem and Progenitor Cell Death and Bone Marrow Failure. Blood, 128 (22). WASHINGTON: AMER SOC HEMATOLOGY. ISSN 1528-0020

Koliaraki, V., Pasparakis, M. ORCID: 0000-0002-9870-0966 and Kollias, G. (2016). Intestinal mesenchymal-specific IKK2 promotes initiation of colitis and colitis-associated cancer. J. Crohns Colitis, 10. S. S103 - 1. OXFORD: OXFORD UNIV PRESS. ISSN 1876-4479

Wachsmuth, E., Aghdam, S. Y., Guenschmann, C., Akyuez, M. D., Pasparakis, M. ORCID: 0000-0002-9870-0966, Bruening, J. C. and Niessen, C. M. (2016). Map kinase p38alpha stress signaling repairs skin barrier defects caused by loss of insulin/IGF-1 signaling. Exp. Dermatol., 25 (3). S. E6 - 1. HOBOKEN: WILEY-BLACKWELL. ISSN 1600-0625

Vlantis, Katerina, Wullaert, Andy ORCID: 0000-0001-5012-654X, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Dannappel, Marius, Schwarzer, Robin, Welz, Patrick, Corona, Teresa, Walczak, Henning ORCID: 0000-0002-6312-4591, Weih, Falk, Klein, Ulf, Kelliher, Michelle and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2016). NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-kappa B-Dependent and -Independent Functions. Immunity, 44 (3). S. 553 - 568. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

Reale, Carla ORCID: 0000-0001-7682-4784, Iervolino, Anna, Scudiero, Ivan, Ferravante, Angela, D'Andrea, Luca Egildo, Mazzone, Pellegrino, Zotti, Tiziana, Leonardi, Antonio, Roberto, Luca, Zannini, Mariastella, de Cristofaro, Tiziana, Shanmugakonar, Muralitharan, Capasso, Giovambattista ORCID: 0000-0003-3469-8614, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Vito, Pasquale and Stilo, Romania (2016). NF-B Essential Modulator (NEMO) Is Critical for Thyroid Function. J. Biol. Chem., 291 (11). S. 5765 - 5774. BETHESDA: AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC. ISSN 1083-351X

Koehler, Ulrike A., Boehm, Friederike, Rolfs, Frank, Egger, Michele, Hornemann, Thorsten, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Weber, Achim and Werner, Sabine (2016). NF-kappa B/RelA and Nrf2 cooperate to maintain hepatocyte integrity and to prevent development of hepatocellular adenoma. J. Hepatol., 64 (1). S. 94 - 103. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1600-0641

Wroblewski, Raluca, Armaka, Marietta, Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Walczak, Henning ORCID: 0000-0002-6312-4591, Mittruecker, Hans-Willi, Schramm, Christoph, Lohse, Ansgar W., Kollias, George ORCID: 0000-0003-1867-3150 and Ehlken, Hanno (2016). Opposing Role of Tumor Necrosis Factor Receptor 1 Signaling in T Cell-Mediated Hepatitis and Bacterial Infection in Mice. Hepatology, 64 (2). S. 508 - 522. HOBOKEN: WILEY-BLACKWELL. ISSN 1527-3350

Najjar, Malek, Saleh, Danish, Zelic, Matija, Nogusa, Shoko, Shah, Saumil, Tai, Albert, Finger, Joshua N., Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Gough, Peter J., Bertin, John, Whalen, Michael J., Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Balachandran, Siddharth, Kelliher, Michelle, Poltorak, Alexander and Degterev, Alexei (2016). RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4. Immunity, 45 (1). S. 46 - 60. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

Lin, Juan, Kumari, Snehlata, Kim, Chun ORCID: 0000-0001-9497-708X, Van, Trieu-My, Wachsmuth, Laurens, Polykratis, Apostolos ORCID: 0000-0001-6720-3302 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2016). RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature, 540 (7631). S. 124 - 137. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Ito, Yasushi, Ofengeim, Dimitry, Najafov, Ayaz ORCID: 0000-0002-1350-2056, Das, Sudeshna ORCID: 0000-0002-9486-6811, Saberi, Shahram, Li, Ying, Hitomi, Junichi, Zhu, Hong ORCID: 0000-0002-2575-4031, Chen, Hongbo ORCID: 0000-0002-9084-7277, Mayo, Lior ORCID: 0000-0002-1296-6692, Geng, Jiefei, Amin, Palak ORCID: 0000-0001-5617-8703, DeWitt, Judy Park, Mookhtiar, Adnan Kasim, Florez, Marcus, Ouchida, Amanda Tomie, Fan, Jian-bing, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Kelliher, Michelle A., Ravits, John and Yuan, Junying (2016). RIPK1 mediates axonal degeneration by promoting inflammation and necroptosis in ALS. Science, 353 (6299). S. 603 - 609. WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1095-9203

Kumari, S., Van, T. and Pasparakis, M. ORCID: 0000-0002-9870-0966 (2016). Role of RIP kinase signalling in the development of skin inflammation in mice with keratinocyte-specific IKK deficiency. J. Invest. Dermatol., 136 (9). S. S218 - 1. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1523-1747

Vlantis, Katerina, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Welz, Patrick-Simon ORCID: 0000-0001-8370-625X, van Loo, Geert, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Wullaert, Andy ORCID: 0000-0001-5012-654X (2016). TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice. Gut, 65 (6). S. 935 - 944. LONDON: BMJ PUBLISHING GROUP. ISSN 1468-3288

Klemann, Christian ORCID: 0000-0002-5639-8690, Pannicke, Ulrich, Morris-Rosendahl, Deborah J., Vlantis, Katerina, Rizzi, Marta, Uhlig, Holm, Vraetz, Thomas, Speckmann, Carsten ORCID: 0000-0002-6217-1556, Strahm, Brigitte, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Schwarz, Klaus, Ehl, Stephan and Rohr, Jan C. (2016). Transplantation from a symptomatic carrier sister restores host defenses but does not prevent colitis in NEMO deficiency. Clin. Immunol., 164. S. 52 - 57. SAN DIEGO: ACADEMIC PRESS INC ELSEVIER SCIENCE. ISSN 1521-7035

Strilic, Boris, Yang, Lida, Albarran-Juarez, Julian, Wachsmuth, Laurens, Han, Kang, Mueller, Ulrike C., Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Offermanns, Stefan ORCID: 0000-0001-8676-6805 (2016). Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis. Nature, 536 (7615). S. 215 - 235. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Koerbelin, Jakob, Dogbevia, Godwin, Michelfelder, Stefan, Ridder, Dirk A., Hunger, Agnes, Wenzel, Jan, Seismann, Henning, Lampe, Melanie, Bannach, Jacqueline, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Kleinschmidt, Juergen A., Schwaninger, Markus and Trepel, Martin (2016). A brain microvasculature endothelial cell-specific viral vector with the potential to treat neurovascular and neurological diseases. EMBO Mol. Med., 8 (6). S. 609 - 626. HOBOKEN: WILEY-BLACKWELL. ISSN 1757-4684

Piaggio, F., Kondylis, V., Pastorino, F., Di Paolo, D., Perri, P., Cossu, I., Schorn, F., Marinaccio, C., Murgia, D., Daga, A., Raggi, F., Loi, M., Emionite, L., Ognio, E., Pasparakis, M. ORCID: 0000-0002-9870-0966, Ribatti, D., Ponzoni, M. and Brignole, C. (2016). A novel liposomal Clodronate depletes tumor-associated macrophages in primary and metastatic melanoma: Anti-angiogenic and anti-tumor effects. J. Control. Release, 223. S. 165 - 178. AMSTERDAM: ELSEVIER. ISSN 1873-4995

Fernandez-Majada, Vanesa, Welz, Patrick-Simon ORCID: 0000-0001-8370-625X, Ermolaeva, Maria A., Schell, Michael, Adam, Alexander, Dietlein, Felix, Komander, David, Buettner, Reinhard, Thomas, Roman K., Schumacher, Bjoern and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2016). The tumour suppressor CYLD regulates the p53 DNA damage response. Nat. Commun., 7. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Ridder, Dirk A., Wenzel, Jan, Mueller, Kristin, Toellner, Kathrin, Tong, Xin-Kang, Assmann, Julian C., Stroobants, Stijn, Weber, Tobias, Niturad, Cristina, Fischer, Lisanne, Lembrich, Beate, Wolburg, Hartwig, Grand'Maison, Marilyn, Papadopoulos, Panayiota, Korpos, Eva, Truchetet, Francois, Rades, Dirk, Sorokin, Lydia M., Schmidt-Supprian, Marc ORCID: 0000-0002-8543-6166, Bedell, Barry J., Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Balschun, Detlef, D'Hooge, Rudi, Loescher, Wolfgang, Hamel, Edith and Schwaninger, Markus ORCID: 0000-0002-4510-9718 (2015). Brain endothelial TAK1 and NEMO safeguard the neurovascular unit. J. Exp. Med., 212 (10). S. 1529 - 1550. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-9538

Eftychi, Christina and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2015). Epithelial IKK alpha licenses ILC3s to defend the intestinal barrier. J. Exp. Med., 212 (10). S. 1483 - 1484. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-9538

Roderick, Justine R., Hermance, Nicole C., Zelic, Matija, Polykratis, Apostolos, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kelliher, Michelle A. (2015). Hematopoietic RIPK1 deficiency results in bone marrow failure due to apoptosis and RIPK3-mediated necroptosis. Clin. Cancer Res., 21. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 1557-3265

Koliaraki, Vasiliki ORCID: 0000-0003-1694-6987, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kollias, George (2015). IKK beta in intestinal mesenchymal cells promotes initiation of colitis-associated cancer. J. Exp. Med., 212 (13). S. 2235 - 2252. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-9538

Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Polykratis, Apostolos, Ehlken, Hanno, Ochoa-Callejero, Laura ORCID: 0000-0001-5366-6613, Straub, Beate Katharina, Krishna-Subramanian, Santosh, Van, Trieu-My, Curth, Harald-Morten, Heise, Nicole, Weih, Falk, Klein, Ulf, Schirmacher, Peter, Kelliher, Michelle and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2015). NEMO Prevents Steatohepatitis and Hepatocellular Carcinoma by Inhibiting RIPK1 Kinase Activity-Mediated Hepatocyte Apoptosis. Cancer Cell, 28 (5). S. 582 - 599. CAMBRIDGE: CELL PRESS. ISSN 1878-3686

Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Vandenabeele, Peter ORCID: 0000-0002-6669-8822 (2015). Necroptosis and its role in inflammation. Nature, 517 (7534). S. 311 - 321. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Dan, Han C., Ebbs, Aaron, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Van Dyke, Terry, Basseres, Daniela S. and Baldwin, Albert S. (2014). Akt-dependent Activation of mTORC1 Complex Involves Phosphorylation of mTOR (Mammalian Target of Rapamycin) by I kappa B Kinase alpha (IKK alpha). J. Biol. Chem., 289 (36). S. 25227 - 25241. BETHESDA: AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC. ISSN 1083-351X

Kumari, S., Bonnet, M., Witte, E., Wolk, K., Kollias, G., Sabat, R., Pasparakis, M. ORCID: 0000-0002-9870-0966 and Haase, I. (2014). Altered tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice. Exp. Dermatol., 23 (3). S. E34 - 1. HOBOKEN: WILEY-BLACKWELL. ISSN 1600-0625

Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Hermance, Nicole, Zelic, Matija, Roderick, Justine, Kim, Chun ORCID: 0000-0001-9497-708X, Lee, Thomas H., Chan, Francis K. M., Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kelliher, Michelle A. (2014). Cutting Edge: RIPK1 Kinase Inactive Mice Are Viable and Protected from TNF-Induced Necroptosis In Vivo. J. Immunol., 193 (4). S. 1539 - 1544. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

Ehlken, H., Krishna-Subramanian, S., Ochoa-Callejero, L., Kondylis, V., Nadi, N. E., Straub, B. K., Schirmacher, P., Walczak, H., Kollias, G. and Pasparakis, M. ORCID: 0000-0002-9870-0966 (2014). Death receptor-independent FADD signalling triggers hepatitis and hepatocellular carcinoma in mice with liver parenchymal cell-specific NEMO knockout. Cell Death Differ., 21 (11). S. 1721 - 1733. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5403

Kim, Chun ORCID: 0000-0001-9497-708X and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2014). Epidermal p65/NF-kappa B signalling is essential for skin carcinogenesis. EMBO Mol. Med., 6 (7). S. 970 - 984. HOBOKEN: WILEY. ISSN 1757-4684

Heise, Nicole, De Silva, Nilushi S., Silva, Kathryn, Carette, Amanda, Simonetti, Giorgia ORCID: 0000-0001-6954-969X, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Klein, Ulf (2014). Germinal center B cell maintenance and differentiation are controlled by distinct NF-kappa B transcription factor subunits. J. Exp. Med., 211 (10). S. 2103 - 2119. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-9538

Roderick, Justine E., Hermance, Nicole, Zelic, Matija, Simmons, Matthew J., Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Kelliher, Michelle A. (2014). Hematopoietic RIPK1 deficiency results in bone marrow failure caused by apoptosis and RIPK3-mediated necroptosis. Proc. Natl. Acad. Sci. U. S. A., 111 (40). S. 14436 - 14442. WASHINGTON: NATL ACAD SCIENCES. ISSN 0027-8424

Liu, Yang, Liu, Xu, Hao, Wenlin, Decker, Yann, Schomburg, Robert, Fueloep, Livia, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Menger, Michael D. and Fassbender, Klaus ORCID: 0000-0003-3596-868X (2014). IKK beta Deficiency in Myeloid Cells Ameliorates Alzheimer's Disease-Related Symptoms and Pathology. J. Neurosci., 34 (39). S. 12982 - 13000. WASHINGTON: SOC NEUROSCIENCE. ISSN 0270-6474

Lu, Huayi, Lu, Qingxian, Gaddipati, Subhash ORCID: 0000-0002-5323-5466, Kasetti, Ramesh Babu, Wang, Wei, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Kaplan, Henry J. and Li, Qiutang (2014). IKK2 Inhibition Attenuates Laser-Induced Choroidal Neovascularization. PLoS One, 9 (1). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Saliba, David G., Heger, Andreas ORCID: 0000-0001-7720-0447, Eames, Hayley L., Oikonomopoulos, Spyros, Teixeira, Ana, Blazek, Katrina ORCID: 0000-0002-4439-4756, Androulidaki, Ariadne, Wong, Daniel, Goh, Fui G., Weiss, Miriam, Byrne, Adam ORCID: 0000-0001-8352-3007, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Ragoussis, Jiannis and Udalova, Irina A. (2014). IRF5:RelA Interaction Targets Inflammatory Genes in Macrophages. Cell Reports, 8 (5). S. 1308 - 1318. CAMBRIDGE: CELL PRESS. ISSN 2211-1247

Carnevalli, Larissa S., Scognamiglio, Roberta, Cabezas-Wallscheid, Nina, Rahmig, Susann, Laurenti, Elisa ORCID: 0000-0002-9917-9092, Masuda, Kohei, Joeckel, Lars, Kuck, Andrea, Sujer, Stefanie, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Erlacher, Miriam, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Essers, Marieke A. G. and Trumpp, Andreas ORCID: 0000-0002-6212-3466 (2014). Improved HSC reconstitution and protection from inflammatory stress and chemotherapy in mice lacking granzyme B. J. Exp. Med., 211 (5). S. 769 - 780. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-9538

Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Haase, Ingo and Nestle, Frank O. (2014). Mechanisms regulating skin immunity and inflammation. Nat. Rev. Immunol., 14 (5). S. 289 - 302. LONDON: NATURE PUBLISHING GROUP. ISSN 1474-1741

Kondylis, V., Ehlken, H. and Pasparakis, M. ORCID: 0000-0002-9870-0966 (2014). NF-kappa B-DEPENDENT AND INDEPENDENT ROLES OF NEMO (IKK gamma) IN THE DEVELOPMENT OF CHRONIC LIVER INFLAMMATION AND HCC. J. Hepatol., 60 (1). S. S39 - 1. AMSTERDAM: ELSEVIER SCIENCE BV. ISSN 1600-0641

Srivastava, Kshitij, Hu, Junhao, Korn, Claudia, Savant, Soniya ORCID: 0000-0003-2730-8526, Teichert, Martin, Kapel, Stephanie S., Jugold, Manfred, Besemfelder, Eva, Thomas, Markus, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Augustin, Hellmut G. (2014). Postsurgical Adjuvant Tumor Therapy by Combining Anti-Angiopoietin-2 and Metronomic Chemotherapy Limits Metastatic Growth. Cancer Cell, 26 (6). S. 880 - 896. CAMBRIDGE: CELL PRESS. ISSN 1878-3686

Kim, C. and Pasparakis, M. ORCID: 0000-0002-9870-0966 (2014). RIP kinase 3 in necroptosis: does it take two or more to kill? Cell Death Differ., 21 (10). S. 1505 - 1508. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5403

Dannappel, Marius, Vlantis, Katerina, Kumari, Snehlata, Polykratis, Apostolos ORCID: 0000-0001-6720-3302, Kim, Chun ORCID: 0000-0001-9497-708X, Wachsmuth, Laurens, Eftychi, Christina, Lin, Juan, Corona, Teresa, Hermance, Nicole, Zelic, Matija, Kirsch, Petra, Basic, Marijana, Bleich, Andre, Kelliher, Michelle and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2014). RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature, 513 (7516). S. 90 - 107. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Kumari, Snehlata, Redouane, Younes, Lopez-Mosqueda, Jaime, Shiraishi, Ryoko, Romanowska, Malgorzata, Lutzmayer, Stefan, Kuiper, Jan, Martinez, Conception, Dikic, Ivan ORCID: 0000-0001-8156-9511, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Ikeda, Fumiyo ORCID: 0000-0003-0407-2768 (2014). Sharpin prevents skin inflammation by inhibiting TNFR1-induced keratinocyte apoptosis. eLife, 3. CAMBRIDGE: ELIFE SCIENCES PUBLICATIONS LTD. ISSN 2050-084X

Linkermann, Andreas ORCID: 0000-0001-6287-9725, Skouta, Rachid ORCID: 0000-0003-3324-4362, Himmerkus, Nina ORCID: 0000-0002-2910-6728, Mulay, Shrikant R., Dewitz, Christin, De Zen, Federica, Prokai, Agnes, Zuchtriegel, Gabriele, Krombach, Fritz, Welz, Patrick-Simon ORCID: 0000-0001-8370-625X, Weinlich, Ricardo ORCID: 0000-0001-6822-7330, Vanden Berghe, Tom, Vandenabeele, Peter ORCID: 0000-0002-6669-8822, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Bleich, Markus ORCID: 0000-0002-1745-2295, Weinberg, Joel M., Reichel, Christoph A., Braesen, Jan Hinrich, Kunzendorf, Ulrich, Anders, Hans-Joachim ORCID: 0000-0003-2434-2956, Stockwell, Brent R., Green, Douglas R. and Krautwald, Stefan (2014). Synchronized renal tubular cell death involves ferroptosis. Proc. Natl. Acad. Sci. U. S. A., 111 (47). S. 16836 - 16842. WASHINGTON: NATL ACAD SCIENCES. ISSN 0027-8424

Eguether, Thibaut ORCID: 0000-0003-1891-9253, Ermolaeva, Maria A., Zhao, Yongge, Bonnet, Marion C., Jain, Ashish, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Courtois, Gilles and Tassin, Anne-Marie (2014). The deubiquitinating enzyme CYLD controls apical docking of basal bodies in ciliated epithelial cells. Nat. Commun., 5. LONDON: NATURE PUBLISHING GROUP. ISSN 2041-1723

Perez-Nazario, Nelissa, Rangel-Moreno, Javier ORCID: 0000-0002-9738-1182, O'Reilly, Michael A., Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Gigliotti, Francis and Wright, Terry W. (2013). Selective Ablation of Lung Epithelial IKK2 Impairs Pulmonary Th17 Responses and Delays the Clearance of Pneumocystis. J. Immunol., 191 (9). S. 4720 - 4731. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 1550-6606

Kumari, Snehlata ORCID: 0000-0002-4971-3162, Bonnet, Marion C., Ulvmar, Maria H., Wolk, Kerstin, Karagianni, Niki, Witte, Ellen, Uthoff-Hachenberg, Claudia, Renauld, Jean-Christophe ORCID: 0000-0003-1736-2131, Kollias, George ORCID: 0000-0003-1867-3150, Toftgard, Rune, Sabat, Robert, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and Haase, Ingo (2013). Tumor Necrosis Factor Receptor Signaling in Keratinocytes Triggers Interleukin-24-Dependent Psoriasis-like Skin Inflammation in Mice. Immunity, 39 (5). S. 899 - 912. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

Polykratis, Apostolos ORCID: 0000-0001-6720-3302, van Loo, Geert, Xanthoulea, Sofia, Hellmich, Martin ORCID: 0000-0001-5174-928X and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2012). Conditional Targeting of Tumor Necrosis Factor Receptor-Associated Factor 6 Reveals Opposing Functions of Toll-Like Receptor Signaling in Endothelial and Myeloid Cells in a Mouse Model of Atherosclerosis. Circulation, 126 (14). S. 1739 - 1770. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1524-4539

Braehler, Sebastian, Ising, Christina ORCID: 0000-0002-7267-3488, Hagmann, Henning, Rasmus, Melanie, Hoehne, Martin, Kurschat, Christine, Kisner, Tuelay, Goebel, Heike, Shankland, Stuart, Addicks, Klaus, Thaiss, Friedrich ORCID: 0000-0002-0357-4726, Schermer, Bernhard ORCID: 0000-0002-5194-9000, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Benzing, Thomas and Brinkkoetter, Paul Thomas (2012). Intrinsic proinflammatory signaling in podocytes contributes to podocyte damage and prolonged proteinuria. Am. J. Physiol.-Renal Physiol., 303 (10). S. F1473 - 13. BETHESDA: AMER PHYSIOLOGICAL SOC. ISSN 1931-857X

Bonnet, Marion C., Preukschat, Daniela, Welz, Patrick-Simon ORCID: 0000-0001-8370-625X, van Loo, Geert, Ermolaeva, Maria A., Bloch, Wilhelm, Haase, Ingo and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2011). The Adaptor Protein FADD Protects Epidermal Keratinocytes from Necroptosis In Vivo and Prevents Skin Inflammation. Immunity, 35 (4). S. 572 - 583. CAMBRIDGE: CELL PRESS. ISSN 1097-4180

Welz, Patrick-Simon ORCID: 0000-0001-8370-625X, Wullaert, Andy ORCID: 0000-0001-5012-654X, Vlantis, Katerina, Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Fernandez-Majada, Vanesa, Ermolaeva, Maria, Kirsch, Petra, Sterner-Kock, Anja, van Loo, Geert and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2011). FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation. Nature, 477 (7364). S. 330 - 336. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Ehlken, Hanno, Kondylis, Vangelis ORCID: 0000-0002-6970-8731, Heinrichsdorff, Jan, Ochoa-Callejero, Laura ORCID: 0000-0001-5366-6613, Roskams, Tania ORCID: 0000-0002-2816-1530 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2011). Hepatocyte IKK2 Protects Mdr2(-/-) Mice from Chronic Liver Failure. PLoS One, 6 (10). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Schnitger, Anna K. D., Machova, Alzbeta, Mueller, Roman Ulrich, Androulidaki, Ariadne, Schermer, Bernhard ORCID: 0000-0002-5194-9000, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Kroenke, Martin and Papadopoulou, Nikoletta (2011). Listeria monocytogenes Infection in Macrophages Induces Vacuolar-Dependent Host miRNA Response. PLoS One, 6 (11). SAN FRANCISCO: PUBLIC LIBRARY SCIENCE. ISSN 1932-6203

Isfort, Katrin, Ebert, Franziska, Bornhorst, Julia, Sargin, Sarah, Kardakaris, Rozina, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Baehler, Martin, Schwerdtle, Tanja, Schwab, Albrecht and Hanley, Peter J. (2011). Real-time Imaging Reveals That P2Y(2) and P2Y(12) Receptor Agonists Are Not Chemoattractants and Macrophage Chemotaxis to Complement C5a Is Phosphatidylinositol 3-Kinase (PI3K)- and p38 Mitogen-activated Protein Kinase (MAPK)-independent. J. Biol. Chem., 286 (52). S. 44776 - 44788. ROCKVILLE: AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC. ISSN 1083-351X

Mc Guire, Conor, Volckaert, Thomas, Wolke, Uta, Sze, Mozes, de Rycke, Riet, Waisman, Ari ORCID: 0000-0003-4304-8234, Prinz, Marco, Beyaert, Rudi ORCID: 0000-0002-5704-582X, Pasparakis, Manolis ORCID: 0000-0002-9870-0966 and van Loo, Geert (2010). Oligodendrocyte-Specific FADD Deletion Protects Mice from Autoimmune-Mediated Demyelination. J. Immunol., 185 (12). S. 7646 - 7654. BETHESDA: AMER ASSOC IMMUNOLOGISTS. ISSN 0022-1767

Schramek, Daniel ORCID: 0000-0001-9977-2104, Leibbrandt, Andreas, Sigl, Verena, Kenner, Lukas ORCID: 0000-0003-2184-1338, Pospisilik, John A., Lee, Heather J., Hanada, Reiko, Joshi, Purna A., Aliprantis, Antonios, Glimcher, Laurie, Pasparakis, Manolis ORCID: 0000-0002-9870-0966, Khokha, Rama, Ormandy, Christopher J., Widschwendter, Martin ORCID: 0000-0002-7778-8380, Schett, Georg and Penninger, Josef M. (2010). Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer. Nature, 468 (7320). S. 98 - 105. BERLIN: NATURE RESEARCH. ISSN 1476-4687

Book Section, Proceedings Item or annotation in a legal commentary

Kumari, Snehlata and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2017). Epithelial Cell Death and Inflammation in Skin. In: Current Topics in Microbiology and Immunology, S. 77 - 94. BERLIN: SPRINGER-VERLAG BERLIN. ISBN 978-3-319-23913-2; 978-3-319-23912-5

Thesis

Schünke, Hannah, Göbel, Ulrike, Dikic, Ivan ORCID: 0000-0001-8156-9511 and Pasparakis, Manolis ORCID: 0000-0002-9870-0966 (2021). The role of OTULIN in skin inflammation and cell death. PhD thesis, Universität zu Köln.