Universität zu Köln

Journal Article

Ecker, Jonas, Selt, Florian, Sturm, Dominik ORCID: 0000-0003-0250-1696, Sill, Martin, Korshunov, Andrey, Hirsch, Steffen, Capper, David ORCID: 0000-0003-1945-497X, Dikow, Nicola, Sutter, Christian, Mueller, Carina, Sigaud, Romain, Eggert, Angelika ORCID: 0000-0003-3476-8184, Simon, Thorsten, Niehues, Tim, von Deimling, Andreas ORCID: 0000-0002-5863-540X, Pajtler, Kristian W., van Tilburg, Cornelis M., Jones, David T. W. ORCID: 0000-0002-2036-5141, Sahm, Felix, Pfister, Stefan M., Witt, Olaf and Milde, Till ORCID: 0000-0002-7267-1052 (2023). Original Research Molecular diagnostics enables detection of actionable targets: the Pediatric Targeted Therapy 2.0 registry. Eur. J. Cancer, 180. S. 71 - 85. OXFORD: ELSEVIER SCI LTD. ISSN 1879-0852

Lodrini, Marco ORCID: 0000-0003-4434-529X, Wuenschel, Jasmin, Thole-Kliesch, Theresa M., Grimaldi, Maddalena, Sprussel, Annika, Linke, Rasmus B., Hollander, Jan F., Tiburtius, Daniela, Kunkele, Annette ORCID: 0000-0002-8406-5412, Schulte, Johannes H., Lankes, Erwin, Elgeti, Thomas, Hundsdorfer, Patrick, Astrahantseff, Kathy, Simon, Thorsten ORCID: 0000-0002-3425-8451, Eggert, Angelika ORCID: 0000-0003-3476-8184 and Deubzer, Hedwig E. (2022). Circulating Cell-Free DNA Assessment in Biofluids from Children with Neuroblastoma Demonstrates Feasibility and Potential for Minimally Invasive Molecular Diagnostics. Cancers, 14 (9). BASEL: MDPI. ISSN 2072-6694

Jazmati, Danny, Hero, Barbara, Thole-Kliesch, Theresa M., Merta, Julien, Deubzer, Hedwig E., Baeumer, Christian, Heinzelmann, Feline, Schleithoff, Stefanie Schulze, Koerber, Friederike, Eggert, Angelika ORCID: 0000-0003-3476-8184, Schwarz, Rudolf, Simon, Thorsten ORCID: 0000-0002-3425-8451 and Timmermann, Beate (2022). Efficacy and Feasibility of Proton Beam Therapy in Relapsed High-Risk Neuroblastoma-Experiences from the Prospective KiProReg Registry. Curr. Oncol., 29 (11). S. 8222 - 8235. BASEL: MDPI. ISSN 1718-7729

Berlak, Mareike ORCID: 0000-0003-4437-3477, Tucker, Elizabeth ORCID: 0000-0003-3716-6605, Dorel, Mathurin, Winkler, Annika, McGearey, Aleixandria, Rodriguez-Fos, Elias ORCID: 0000-0002-2555-0178, da Costa, Barbara Martins, Barker, Karen, Fyle, Elicia, Calton, Elizabeth, Eising, Selma, Ober, Kim, Hughes, Deborah, Koutroumanidou, Eleni, Carter, Paul, Stankunaite, Reda, Proszek, Paula ORCID: 0000-0002-0780-6790, Jain, Neha ORCID: 0000-0002-8499-3366, Rosswog, Carolina, Dorado-Garcia, Heathcliff, Molenaar, Jan Jasper, Hubank, Mike, Barone, Giuseppe, Anderson, John, Lang, Peter, Deubzer, Hedwig Elisabeth, Kuenkele, Annette, Fischer, Matthias, Eggert, Angelika ORCID: 0000-0003-3476-8184, Kloft, Charlotte, Henssen, Anton George, Boettcher, Michael, Hertwig, Falk, Bluthgen, Nils, Chesler, Louis and Schulte, Johannes Hubertus ORCID: 0000-0003-0671-1201 (2022). Mutations in ALK signaling pathways conferring resistance to ALK inhibitor treatment lead to collateral vulnerabilities in neuroblastoma cells. Mol. Cancer, 21 (1). LONDON: BMC. ISSN 1476-4598

Reschke, Madlen ORCID: 0000-0003-1706-1160, Biewald, Eva, Bronstein, Leo, Brecht, Ines B., Dittner-Moormann, Sabine, Driever, Frank, Ebinger, Martin ORCID: 0000-0002-4229-8058, Fleischhack, Gudrun ORCID: 0000-0001-5714-007X, Grabow, Desiree, Geismar, Dirk, Goricke, Sophia, Guberina, Maja, Le Guin, Claudia H. D., Kiefer, Tobias, Kratz, Christian P., Metz, Klaus, Muller, Bert, Ryl, Tatsiana, Schlamann, Marc, Schluter, Sabrina, Schonberger, Stefan ORCID: 0000-0002-7222-296X, Schulte, Johannes H., Sirin, Selma ORCID: 0000-0003-4555-0367, Susskind, Daniela, Timmermann, Beate, Ting, Saskia ORCID: 0000-0003-1415-7714, Wackernagel, Werner, Wieland, Regina, Zenker, Martin, Zeschnigk, Michael, Reinhardt, Dirk ORCID: 0000-0002-7027-4483, Eggert, Angelika ORCID: 0000-0003-3476-8184, Ritter-Sovinz, Petra, Lohmann, Dietmar R., Bornfeld, Norbert, Bechrakis, Nikolaos and Ketteler, Petra ORCID: 0000-0002-8138-0441 (2021). Eye Tumors in Childhood as First Sign of Tumor Predisposition Syndromes: Insights from an Observational Study Conducted in Germany and Austria. Cancers, 13 (8). BASEL: MDPI. ISSN 2072-6694

Szymansky, Annabell, Kruetzfeldt, Louisa-Marie ORCID: 0000-0003-3630-3727, Heukamp, Lukas C., Hertwig, Falk, Theissen, Jessica, Deubzer, Hedwig E., Willing, Eva-Maria, Menon, Roopika, Fuchs, Steffen ORCID: 0000-0001-9619-4329, Thole, Theresa, Schulte, Stefanie, Schmelz, Karin, Kuenkele, Annette, Lang, Peter, Fuchs, Joerg, Eggert, Angelika ORCID: 0000-0003-3476-8184, Eckert, Cornelia, Fischer, Matthias, Henssen, Anton G., Rodriguez-Fos, Elias ORCID: 0000-0002-2555-0178 and Schulte, Johannes H. (2021). Neuroblastoma Risk Assessment and Treatment Stratification with Hybrid Capture-Based Panel Sequencing. J. Pers. Med., 11 (8). BASEL: MDPI. ISSN 2075-4426

van Tilburg, Cornelis M., Pfaff, Elke, Pajtler, Kristian W., Langenberg, Karin P. S., Fiesel, Petra, Jones, Barbara C., Balasubramanian, Gnana Prakash, Stark, Sebastian, Johann, Pascal D., Blattner-Johnson, Mirjam, Schramm, Kathrin, Dikow, Nicola, Hirsch, Steffen, Sutter, Christian, Grund, Kerstin, von Stackelberg, Arend, Kulozik, Andreas E., Lissat, Andrej, Borkhardt, Arndt, Meisel, Roland, Reinhardt, Dirk, Klusmann, Jan-Henning ORCID: 0000-0002-1070-0727, Fleischhack, Gudrun, Tippelt, Stephan, von Schweinitz, Dietrich, Schmid, Irene, Kramm, Christof M., von Bueren, Andre O., Calaminus, Gabriele, Vorwerk, Peter, Graf, Norbert ORCID: 0000-0002-2248-323X, Westermann, Frank, Fischer, Matthias, Eggert, Angelika ORCID: 0000-0003-3476-8184, Burkhardt, Birgit, Woessmann, Wilhelm, Nathrath, Michaela, Hecker-Nolting, Stefanie, Fruehwald, Michael C., Schneider, Dominik T. ORCID: 0000-0001-8153-1601, Brecht, Ines B., Ketteler, Petra, Fulda, Simone ORCID: 0000-0002-0459-6417, Koscielniak, Ewa, Meister, Michael T., Scheer, Monika, Hettmer, Simone, Schwab, Matthias, Tremmel, Roman, Ora, Ingrid, Hutter, Caroline, Gerber, Nicolas U., Lohi, Olli, Kazanowska, Bernarda ORCID: 0000-0002-7198-9122, Kattamis, Antonis, Filippidou, Maria, Goemans, Bianca, Zwaan, C. Michel, Milde, Till, Jaeger, Natalie, Wolf, Stephan, Reuss, David, Sahm, Felix ORCID: 0000-0001-5441-1962, von Deimling, Andreas ORCID: 0000-0002-5863-540X, Dirksen, Uta, Freitag, Angelika, Witt, Ruth, Lichter, Peter, Kopp-Schneider, Annette, Jones, David T. W., Molenaar, Jan J., Capper, David ORCID: 0000-0003-1945-497X, Pfister, Stefan M. and Witt, Olaf (2021). The Pediatric Precision Oncology INFORM Registry: Clinical Outcome and Benefit for Patients with Very High-Evidence Targets. Cancer Discov., 11 (11). S. 2764 - 2780. PHILADELPHIA: AMER ASSOC CANCER RESEARCH. ISSN 2159-8290

Jazmati, Danny, Butzer, Sarina, Hero, Barbara, Ahmad Khalil, Dalia, Merta, Julien, Baumer, Christian, Plum, Gina, Fuchs, Jorg, Koerber, Friederike, Steinmeier, Theresa, Peters, Sarah, Doyen, Jerome, Thole, Theresa, Schmidt, Matthias, Blase, Christoph, Tippelt, Stephan, Eggert, Angelika ORCID: 0000-0003-3476-8184, Schwarz, Rudolf, Simon, Thorsten ORCID: 0000-0002-3425-8451 and Timmermann, Beate (2021). Proton Beam Therapy for Children With Neuroblastoma: Experiences From the Prospective KiProReg Registry. Front. Oncol., 10. LAUSANNE: FRONTIERS MEDIA SA. ISSN 2234-943X

Schmelz, Karin, Toedling, Joern, Huska, Matt, Cwikla, Maja C., Kruetzfeldt, Louisa-Marie, Proba, Jutta, Ambros, Peter F., Ambros, Inge M., Boral, Sengul, Lodrini, Marco, Chen, Celine Y., Burkert, Martin ORCID: 0000-0002-6721-9985, Guergen, Dennis, Szymansky, Annabell, Astrahantseff, Kathy, Kuenkele, Annette, Haase, Kerstin, Fischer, Matthias, Deubzer, Hedwig E., Hertwig, Falk, Hundsdoerfer, Patrick, Henssen, Anton G., Schwarz, Roland F., Schulte, Johannes H. and Eggert, Angelika ORCID: 0000-0003-3476-8184 (2021). Spatial and temporal intratumour heterogeneity has potential consequences for single biopsy-based neuroblastoma treatment decisions. Nat. Commun., 12 (1). BERLIN: NATURE PORTFOLIO. ISSN 2041-1723

Moreno, Lucas, Barone, Giuseppe, DuBois, Steven G., Molenaar, Jan, Fischer, Matthias, Schulte, Johannes, Eggert, Angelika ORCID: 0000-0003-3476-8184, Schleiermacher, Gudrun, Speleman, Frank, Chesler, Louis, Geoerger, Birgit, Hogarty, Michael D., Irwin, Meredith S., Bird, Nick, Blanchard, Guy B., Buckland, Sean, Caron, Hubert, Davis, Susan, De Wilde, Bram, DeubZer, Hedwig E., Dolman, Emmy, Eilers, Martin, George, Rani E., George, Sally, Sterba, Jaroslav, Maris, John M., Marshall, Lynley, Merchant, Melinda, Mortimer, Peter, Owens, Cormac, Philpott, Anna, Poon, Evon, Shay, Jerry W., Tonelli, Roberto, Valteau-Couanet, Dominique, Vassal, Gilles, Park, Julie R. and Pearson, Andrew D. J. (2020). Accelerating drug development for neuroblastoma: Summary of the Second Neuroblastoma Drug Development Strategy forum from Innovative Therapies for Children with Cancer and International Society of Paediatric Oncology Europe Neuroblastoma. Eur. J. Cancer, 136. S. 52 - 69. OXFORD: ELSEVIER SCI LTD. ISSN 1879-0852

Koche, Richard P., Rodriguez-Fos, Elias ORCID: 0000-0002-2555-0178, Helmsauer, Konstantin ORCID: 0000-0003-0773-4114, Burkert, Martin ORCID: 0000-0002-6721-9985, MacArthur, Ian C., Maag, Jesper, Chamorro, Rocio, Munoz-Perez, Natalia, Puiggros, Montserrat, Dorado Garcia, Heathcliff, Bei, Yi, Roeefzaad, Claudia, Bardinet, Victor, Szymansky, Annabell, Winkler, Annika, Thole, Theresa, Timme, Natalie, Kasack, Katharina, Fuchs, Steffen ORCID: 0000-0001-9619-4329, Klironomos, Filippos, Thiessen, Nina, Blanc, Eric, Schmelz, Karin, Kuenkele, Annette, Hundsdoerfer, Patrick, Rosswog, Carolina, Theissen, Jessica, Beule, Dieter, Deubzer, Hedwig, Sauer, Sascha, Toedling, Joern, Fischer, Matthias, Hertwig, Falk ORCID: 0000-0003-4784-6516, Schwarz, Roland F., Eggert, Angelika ORCID: 0000-0003-3476-8184, Torrents, David, Schulte, Johannes H. and Henssen, Anton G. (2020). Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma. Nature Genet., 52 (1). S. 29 - 38. BERLIN: NATURE RESEARCH. ISSN 1546-1718

Desch, Ann-Kathrin, Hartung, Kristin, Botzen, Ante, Brobeil, Alexander, Rummel, Mathias, Kurch, Lars, Georgi, Thomas, Jox, Theresa, Bielack, Stefan, Burdach, Stefan, Classen, Carl Friedrich, Claviez, Alexander, Debatin, Klaus-Michael ORCID: 0000-0002-8397-1886, Ebinger, Martin ORCID: 0000-0002-4229-8058, Eggert, Angelika ORCID: 0000-0003-3476-8184, Faber, Joerg, Flotho, Christian, Fruehwald, Michael, Graf, Norbert ORCID: 0000-0002-2248-323X, Jorch, Norbert, Kontny, Udo, Kramm, Christof, Kulozik, Andreas, Kuehr, Joachim, Sykora, Karl-Walter, Metzler, Markus, Mueller, Hermann L., Nathrath, Michaela, Nuesslein, Thomas, Paulussen, Michael, Pekrun, Arnulf, Reinhardt, Dirk, Reinhard, Harald, Roessig, Claudia, Sauerbrey, Axel, Schlegel, Paul-Gerhardt, Schneider, Dominik T., Scheurlen, Wolfram, Schweigerer, Lothar, Simon, Thorsten, Suttorp, Meinolf, Vorwerk, Peter, Schmitz, Roland, Kluge, Regine, Mauz-Koerholz, Christine, Koerholz, Dieter, Gattenloehner, Stefan and Braeuninger, Andreas (2020). Genotyping circulating tumor DNA of pediatric Hodgkin lymphoma. Leukemia, 34 (1). S. 151 - 167. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-5551

Peitz, Constantin, Spruessel, Annika, Linke, Rasmus B., Astrahantseff, Kathy, Grimaldi, Maddalena, Schmelz, Karin, Toedling, Joern, Schulte, Johannes H., Fischer, Matthias, Messerschmidt, Clemens ORCID: 0000-0001-8632-656X, Beule, Dieter, Keilholz, Ulrich, Eggert, Angelika ORCID: 0000-0003-3476-8184, Deubzer, Hedwig E. and Lodrini, Marco (2020). Multiplexed Quantification of Four Neuroblastoma DNA Targets in a Single Droplet Digital PCR Reaction. J. Mol. Diagn., 22 (11). S. 1309 - 1324. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1943-7811

Scheer, Monika, Blank, Bernd, Bauer, Sebastian ORCID: 0000-0001-5949-8120, Vokuhl, Christian, Stegmaier, Sabine, Feuchtgruber, Simone, Henssen, Anton, Sparber-Sauer, Monika, Eggert, Angelika ORCID: 0000-0003-3476-8184, Handgretinger, Ruppert, Pekrun, Arnulf, Rossig, Claudia, Rutkowski, Stefan, Schlegel, Paul-Gerhardt, Schrappe, Martin, Simon, Thorsten, Kazanowska, Bernarda, Niggli, Felix, Ladenstein, Ruth, Ljungman, Gustaf ORCID: 0000-0002-4949-2494, Jahnukainen, Kirsi, Fuchs, Joerg, Bielack, Stefan S., Koscielniak, Ewa and Klingebiel, Thomas (2020). Synovial sarcoma disease characteristics and primary tumor sites differ between patient age groups: a report of the Cooperative Weichteilsarkom Studiengruppe (CWS). J. Cancer Res. Clin. Oncol., 146 (4). S. 953 - 961. NEW YORK: SPRINGER. ISSN 1432-1335

Lindner, Sven, Bachmann, Hagen S., Odersky, Andrea, Schaefers, Simon, Klein-Hitpass, Ludger, Hero, Barbara, Fischer, Matthias, Eggert, Angelika ORCID: 0000-0003-3476-8184, Schramm, Alexander ORCID: 0000-0001-7670-7529 and Schulte, Johannes H. (2015). Absence of telomerase reverse transcriptase promoter mutations in neuroblastoma. Biomed. Rep., 3 (4). S. 443 - 447. ATHENS: SPANDIDOS PUBL LTD. ISSN 2049-9442

Peifer, Martin ORCID: 0000-0002-5243-5503, Hertwig, Falk ORCID: 0000-0003-4784-6516, Roels, Frederik, Dreidax, Daniel, Gartlgruber, Moritz, Menon, Roopika, Kraemer, Andrea, Roncaioli, Justin L., Sand, Frederik, Heuckmann, Johannes M., Ikram, Fakhera ORCID: 0000-0001-7796-4746, Schmidt, Rene, Ackermann, Sandra, Engesser, Anne, Kahlert, Yvonne, Vogel, Wenzel, Altmueller, Janine, Nuernberg, Peter, Thierry-Mieg, Jean, Thierry-Mieg, Danielle ORCID: 0000-0001-9568-4211, Mariappan, Aruljothi, Heynck, Stefanie, Mariotti, Erika, Henrich, Kai-Oliver, Gloeckner, Christian, Bosco, Graziella, Leuschner, Ivo, Schweiger, Michal R., Savelyeva, Larissa, Watkins, Simon C., Shao, Chunxuan, Bell, Emma, Hoefer, Thomas, Achter, Viktor, Lang, Ulrich ORCID: 0000-0001-7166-0805, Theissen, Jessica, Volland, Ruth, Saadati, Maral, Eggert, Angelika ORCID: 0000-0003-3476-8184, de Wilde, Bram, Berthold, Frank, Peng, Zhiyu, Zhao, Chen, Shi, Leming, Ortmann, Monika, Buettner, Reinhard, Perner, Sven, Hero, Barbara, Schramm, Alexander, Schulte, Johannes H., Herrmann, Carl ORCID: 0000-0003-4989-4722, O'Sullivan, Roderick J., Westermann, Frank, Thomas, Roman K. and Fischer, Matthias (2015). Telomerase activation by genomic rearrangements in high-risk neuroblastoma. Nature, 526 (7575). S. 700 - 705. LONDON: NATURE PUBLISHING GROUP. ISSN 1476-4687

Henssen, Anton ORCID: 0000-0003-1534-778X, Thor, Theresa, Odersky, Andrea, Heukamp, Lukas ORCID: 0000-0002-3388-3482, El-Hindy, Nicolai, Beckers, Anneleen, Slpeleman, Frank, Althoff, Kristina, Schaefers, Simon, Schramm, Alexander ORCID: 0000-0001-7670-7529, Sure, Ulrich, Fleischhack, Gudrun, Eggert, Angelika ORCID: 0000-0003-3476-8184 and Schulte, Johannes Hubertus ORCID: 0000-0003-0671-1201 (2013). BET bromodomain protein inhibition is a therapeutic option for medulloblastoma. Oncotarget, 4 (11). ORCHARD PARK: IMPACT JOURNALS LLC. ISSN 1949-2553

Molenaar, Jan J., Domingo-Fernandez, Raquel, Ebus, Marli E., Lindner, Sven, Koster, Jan ORCID: 0000-0002-0890-7585, Drabek, Ksenija, Mestdagh, Pieter, van Sluis, Peter, Valentijn, Linda J., van Nes, Johan ORCID: 0000-0001-7691-1431, Broekmans, Marloes, Haneveld, Franciska, Volckmann, Richard, Bray, Isabella, Heukamp, Lukas ORCID: 0000-0002-3388-3482, Spruessel, Annika, Thor, Theresa, Kieckbusch, Kristina, Klein-Hitpass, Ludger, Fischer, Matthias, Vandesompele, Jo ORCID: 0000-0001-6274-0184, Schramm, Alexander ORCID: 0000-0001-7670-7529, van Noesel, Max M., Varesio, Luigi, Speleman, Frank, Eggert, Angelika ORCID: 0000-0003-3476-8184, Stallings, Raymond L., Caron, Huib N., Versteeg, Rogier ORCID: 0000-0001-7172-0388 and Schulte, Johannes H. (2012). LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression. Nature Genet., 44 (11). S. 1199 - 1207. NEW YORK: NATURE PUBLISHING GROUP. ISSN 1546-1718