Bachurski, Daniel 
ORCID: 0000-0001-9168-9680 and Hallek, Michael ORCID: 0000-0002-7425-4455
(2025).
Biological and technical complexities in analyzing extracellular vesicle immune interactions in B‐cell malignancies.
FEBS Letters, 599 (20).
pp. 2952-2953.
Wiley.
ISSN 0014-5793
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Abstract
Extracellular vesicles (EVs) mediate intercellular communication within tumor immune microenvironments. However, their role in B-cell malignancies remains poorly defined, owing to biological complexity and technical challenges in EV isolation and analysis. Advancing EV and recipient cell analysis at the single-EV and single-cell level via novel tagging strategies is essential to overcome these obstacles. This graphical review examines the heterogeneity of EV cargo and subpopulation composition from diverse sources, and their immune interactions in the tumor immune microenvironment of B-cell malignancies, while discussing innovative methods for analyzing immune cell EVs and their target cells.
| Item Type: | Article |
| Creators: | Creators Email ORCID ORCID Put Code |
| URN: | urn:nbn:de:hbz:38-805025 |
| Identification Number: | 10.1002/1873-3468.70102 |
| Journal or Publication Title: | FEBS Letters |
| Volume: | 599 |
| Number: | 20 |
| Page Range: | pp. 2952-2953 |
| Number of Pages: | 2 |
| Date: | 4 October 2025 |
| Publisher: | Wiley |
| ISSN: | 0014-5793 |
| Language: | English |
| Faculty: | Faculty of Medicine |
| Divisions: | CECAD - Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases Faculty of Medicine > Innere Medizin > Klinik II für Innere Medizin - Nephrologie, Rheumatologie, Diabetologie und Allgemeine Innere Medizin Faculty of Medicine > Weitere > Centrum für integrierte Onkologie (CIO) Zentrum für Molekulare Medizin |
| Subjects: | Medical sciences Medicine |
| ['eprint_fieldname_oa_funders' not defined]: | Publikationsfonds UzK |
| Refereed: | Yes |
| URI: | http://kups.ub.uni-koeln.de/id/eprint/80502 |
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