Universität zu Köln

Richardson, T. ORCID: 0009-0006-3588-6376, Schütte, D. ORCID: 0000-0002-4746-537X, Feyer, K., Grass, L., Hallek, M., Scheid, C. ORCID: 0009-0007-6539-226X, Simon, F. ORCID: 0000-0002-2700-3717, Braun, T. ORCID: 0000-0002-0854-7815, Fürstenau, M. ORCID: 0000-0002-6593-0140, Gödel, P. ORCID: 0000-0001-7887-8313 and Holtick, U. ORCID: 0000-0002-5543-0257 (2024). Consistent FFP2-masking as part of reducing viral respiratory infections on medical wards for allogeneic hematopoietic stem cell transplantation. Scientific Reports, 14 (1). pp. 1-7. Springer Nature. ISSN 2045-2322

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Abstract

[Artikel-Nr.: 21481] Patients undergoing allogenic hematopoietic stem cell transplantation (allo-HSCT) are highly susceptible to infections. The consequent use of masks on wards for allo-HSCT has been controversial in the past decades and was not common before the COVID-19 pandemic. We retrospectively compared incidence and outcomes of viral respiratory infections during allo-HSCT on our specialized ward between 01/2018 and 09/2020 to the era of FFP2 masking between 10/2020 and 10/2022 covering similar seasons of the year. Each group consisted of 150 matched patients. The usage of FFP2 masks reduced the incidence of viral respiratory infections from 20,7% to 2,0% (p < 0.001). This reduced the time on ward from a median of 26 days to 23.5 days (p = 0.002). It also resulted in less use of CT-scans (p = 0.003) and bronchoalveolar lavage procedures (p = 0.057). Median time to proof of infection was 21 days after admission in both groups. No difference was detected in progression free survival, hospital survival or non-relapse mortality (p = 0.78). Our retrospective results indicate that FFP2 masks worn by patients and hospital staff may help to significantly reduce the incidence of viral respiratory infections, including COVID-19, shorten the in-hospital time, and reduce costs without affecting survival.

Item Type:	Article
Creators:	Creators Email ORCID ORCID Put Code Richardson, T. UNSPECIFIED https://orcid.org/0009-0006-3588-6376 UNSPECIFIED Schütte, D. UNSPECIFIED https://orcid.org/0000-0002-4746-537X UNSPECIFIED Feyer, K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Grass, L. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hallek, M. UNSPECIFIED https://orcid.org/0000-0002-7425-445 UNSPECIFIED Scheid, C. UNSPECIFIED https://orcid.org/0009-0007-6539-226X UNSPECIFIED Simon, F. UNSPECIFIED https://orcid.org/0000-0002-2700-3717 UNSPECIFIED Braun, T. UNSPECIFIED https://orcid.org/0000-0002-0854-7815 UNSPECIFIED Fürstenau, M. UNSPECIFIED https://orcid.org/0000-0002-6593-0140 UNSPECIFIED Gödel, P. UNSPECIFIED https://orcid.org/0000-0001-7887-8313 UNSPECIFIED Holtick, U. UNSPECIFIED https://orcid.org/0000-0002-5543-0257 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-815829
Identification Number:	10.1038/s41598-024-72646-y
Journal or Publication Title:	Scientific Reports
Volume:	14
Number:	1
Page Range:	pp. 1-7
Number of Pages:	7
Date:	14 September 2024
Publisher:	Springer Nature
ISSN:	2045-2322
Language:	English
Faculty:	Faculty of Medicine
Divisions:	Faculty of Medicine > Innere Medizin > Klinik I für Innere Medizin - Hämatologie und Onkologie
Subjects:	Medical sciences Medicine
['eprint_fieldname_oa_funders' not defined]:	Publikationsfonds UzK
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/81582