Universität zu Köln

Schwarzer, Robin, Laurien, Lucie and Pasparakis, Manolis (2020). New insights into the regulation of apoptosis, necroptosis, and pyroptosis by receptor interacting protein kinase 1 and caspase-8. Current Opinion in Cell Biology, 63. pp. 186-193. ISSN 09550674

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Abstract

Necroptosis and pyroptosis are inflammatory forms of regulated necrotic cell death as opposed to apoptosis that is generally considered immunologically silent. Recent studies revealed unexpected links in the pathways regulating and executing cell death in response to activation of signaling cascades inducing apoptosis, necroptosis, and pyroptosis. Emerging evidence suggests that receptor interacting protein kinase 1 and caspase-8 control the cross-talk between apoptosis, necroptosis, and pyroptosis and determine the type of cell death induced in response to activation of cell death signaling.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schwarzer, Robin UNSPECIFIED UNSPECIFIED UNSPECIFIED Laurien, Lucie UNSPECIFIED UNSPECIFIED UNSPECIFIED Pasparakis, Manolis UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-112730
DOI:	10.1016/j.ceb.2020.02.004
Journal or Publication Title:	Current Opinion in Cell Biology
Volume:	63
Page Range:	pp. 186-193
Date:	9 March 2020
ISSN:	09550674
Language:	English
Faculty:	Faculty of Mathematics and Natural Sciences
Divisions:	CECAD - Cluster of Excellence Cellular Stress Responses in Aging-Associated Diseases Faculty of Mathematics and Natural Sciences > Department of Biology > Institute for Genetics
Subjects:	Life sciences
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/11273