Universität zu Köln

Laukamp, Kai Roman ORCID: 0000-0002-5600-5914, Ho, Vivian, Obmann, Verena Carola, Herrmann, Karin, Gupta, Amit, Borggrefe, Jan ORCID: 0000-0003-2908-7560, Lennartz, Simon, Hokamp, Nils Grosse and Ramaiya, Nikhil (2020). Virtual non-contrast for evaluation of liver parenchyma and vessels: results from 25 patients using multi-phase spectral-detector CT. Acta Radiol., 61 (8). S. 1143 - 1153. LONDON: SAGE PUBLICATIONS LTD. ISSN 1600-0455

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Abstract

Background In abdominal imaging, contrast-enhanced computed tomography (CT) examinations are most commonly applied; however, unenhanced examinations are still needed for several clinical questions but require additional scanning and radiation exposure. Purpose To evaluate accuracy of virtual non-contrast (VNC) from arterial and venous phase spectral-detector CT (SDCT) scans compared to true-unenhanced (TNC) images for the evaluation of liver parenchyma and vessels. Material and Methods A total of 25 patients undergoing triphasic SDCT examinations were included. VNC was reconstructed from arterial and venous phases and compared to TNC images. Quantitative image analysis was performed by region of interest (ROI)-based assessment of mean and SD of attenuation (HU) in each liver segment, spleen, portal vein, common hepatic artery, and abdominal aorta. Subjectively, iodine subtraction and diagnostic assessment were rated on 5-point Likert scales. Results Attenuation and image noise measured in the liver from VNC were not significantly different from TNC (TNC: 54.6 +/- 10.8 HU, VNC arterial phase: 55.7 +/- 10.8 HU; VNC venous phase: 58.3 +/- 10.0 HU; P > 0.05). VNC also showed accurate results regarding attenuation and image noise for spleen, portal vein, and abdominal aorta. Only iodine subtraction in the common hepatic artery in the arterial phase was insufficient which was confirmed by the subjective reading. Apart from that, subjective reading showed accurate iodine subtraction and comparable diagnostic assessment. Conclusion VNC from the arterial and venous phases were very similar to TNC yielding mostly negligible differences in attenuation, image noise, and diagnostic utility. Inadequate iodine subtraction occurred in hepatic arteries in the arterial phase.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Laukamp, Kai Roman UNSPECIFIED orcid.org/0000-0002-5600-5914 UNSPECIFIED Ho, Vivian UNSPECIFIED UNSPECIFIED UNSPECIFIED Obmann, Verena Carola UNSPECIFIED UNSPECIFIED UNSPECIFIED Herrmann, Karin UNSPECIFIED UNSPECIFIED UNSPECIFIED Gupta, Amit UNSPECIFIED UNSPECIFIED UNSPECIFIED Borggrefe, Jan UNSPECIFIED orcid.org/0000-0003-2908-7560 UNSPECIFIED Lennartz, Simon UNSPECIFIED UNSPECIFIED UNSPECIFIED Hokamp, Nils Grosse UNSPECIFIED UNSPECIFIED UNSPECIFIED Ramaiya, Nikhil UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-124194
DOI:	10.1177/0284185119893094
Journal or Publication Title:	Acta Radiol.
Volume:	61
Number:	8
Page Range:	S. 1143 - 1153
Date:	2020
Publisher:	SAGE PUBLICATIONS LTD
Place of Publication:	LONDON
ISSN:	1600-0455
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DUAL-ENERGY CT; MACROVESICULAR HEPATIC STEATOSIS; DIAGNOSTIC-ACCURACY; ATTENUATION VALUES; DONORS Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/12419