Froelich, Jan, Wiater, Alfred and Lehmkuhl, Gerd (2019). Melatonin in the treatment of insomnia and sleep-wake rhythm disorders in children and adolescents. Somnologie, 23 (4). S. 261 - 271. CHAM: SPRINGER INTERNATIONAL PUBLISHING AG. ISSN 1439-054X

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Abstract

Background Insomnia and sleep-wake-rhythm disorders occur frequently in children and adolescents and are based on heterogeneous pathogenetic factors. Due to its sleep-promoting and chronobiotic properties, melatonin may be a treatment alternative. Objective and methods Based on Medline research the pharmacologic effect characteristics as well as interactions with other substances and tolerability are described. Moreover, results from treatment studies for insomnia and sleep-wake rhythm disorders, with reference to national and international consensus statements, will be discussed. Results and conclusions Melatonin is an effective and safe option in the short term treatment of insomnia and sleep-wake rhythm disorders in children and adolescents if measures of sleep hygiene and behavior therapy have failed.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Froelich, JanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wiater, AlfredUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lehmkuhl, GerdUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-126059
DOI: 10.1007/s11818-019-0210-z
Journal or Publication Title: Somnologie
Volume: 23
Number: 4
Page Range: S. 261 - 271
Date: 2019
Publisher: SPRINGER INTERNATIONAL PUBLISHING AG
Place of Publication: CHAM
ISSN: 1439-054X
Language: German
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
DELAYED SLEEP; EXOGENOUS MELATONIN; RELEASE MELATONIN; BEHAVIOR PROBLEMS; CONTROLLED-TRIAL; ONSET INSOMNIA; IMPAIRED SLEEP; PHASE SYNDROME; CHILDHOOD; EFFICACYMultiple languages
Clinical NeurologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/12605

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