Universität zu Köln

Mallmann, Michael R. ORCID: 0000-0001-9373-3331, Mack-Detlefsen, Birte, Reutter, Heiko, Pohle, Rebecca, Gottschalk, Ingo, Geipel, Annegret, Berg, Christoph, Boemers, Thomas M. and Gembruch, Ulrich ORCID: 0000-0001-8284-4669 (2019). Isolated bladder exstrophy in prenatal diagnosis. Arch. Gynecol. Obstet., 300 (2). S. 355 - 364. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1432-0711

Full text not available from this repository.

Abstract

PurposeIsolated classic bladder exstrophy (CBE) is the most common variant of the bladder-exstrophy-epispadias complex (BEEC). The BEEC represents a spectrum ranging from isolated epispadias over CBE to the most severe form, cloacal exstrophy. We report on a series of 12 cases with CBE diagnosed prenatally and illustrate the spectrum of prenatal ultrasound findings with comparison to prior published reports on this entity.MethodsThis was a retrospective study involving 12 fetuses with CBE at two large tertiary referral centers in Germany over a 14-year period (2004-2018).ResultsMedian diagnosis was made with ultrasound in 24+5 (IQR(25,75): 21+2, 29+0) weeks of gestation. All fetuses presented with the pathognomonic findings non-visualization of the fetal bladder and protruding abdominal mass below the umbilical cord insertion. All fetuses showed normal kidney anatomy and normal amniotic fluid throughout pregnancy. Epispadia was visible prenatally on ultrasound in 6/8 male fetuses. 1/12 Parents opted for termination of pregnancy, 11/12 fetuses were live born and received reconstructive surgery.ConclusionsIsolated CBE is an extremely rare prenatal sonographic finding. Prenatal diagnostics should exclude additional malformations within the spectrum of cloacal malformations.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Mallmann, Michael R. UNSPECIFIED orcid.org/0000-0001-9373-3331 UNSPECIFIED Mack-Detlefsen, Birte UNSPECIFIED UNSPECIFIED UNSPECIFIED Reutter, Heiko UNSPECIFIED UNSPECIFIED UNSPECIFIED Pohle, Rebecca UNSPECIFIED UNSPECIFIED UNSPECIFIED Gottschalk, Ingo UNSPECIFIED UNSPECIFIED UNSPECIFIED Geipel, Annegret UNSPECIFIED UNSPECIFIED UNSPECIFIED Berg, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Boemers, Thomas M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gembruch, Ulrich UNSPECIFIED orcid.org/0000-0001-8284-4669 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-134319
DOI:	10.1007/s00404-019-05193-x
Journal or Publication Title:	Arch. Gynecol. Obstet.
Volume:	300
Number:	2
Page Range:	S. 355 - 364
Date:	2019
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1432-0711
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SONOGRAPHIC FINDINGS; OEIS COMPLEX Multiple languages Obstetrics & Gynecology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/13431