Steffen, Armin, Jost, Wolfgang, Baeumer, Tobias, Beutner, Dirk, Degenkolb-Weyers, Sabine, Gross, Martin, Grosheva, Maria, Hakim, Samer, Kahl, Kai G., Laskawi, Rainer, Lencer, Rebekka, Loehler, Jan, Meyners, Thekla, Rohrbach-Volland, Saskia, Schoenweiler, Rainer, Schroeder, Sara-Christina, Schroeder, Sebastian, Schroeter-Morasch, Heidrun, Schuster, Maria, Steinlechner, Susanne, Urban, Roland and Guntinas-Lichius, Orlando (2019). Hypersalivation - Update of the S2k guideline (AWMF) in short form. Laryngo-Rhino-Otol., 98 (6). S. 388 - 398. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1438-8685

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Abstract

Hypersalivation describes a relatively excessive salivary flow, which wets the patient himself and his surroundings. It may result because of insufficient oro-motor function, dysphagia, decreased central control and coordination. This update presents recent changes and innovation in the treatment of hypersalivation. Multidisciplinary diagnostic and treatment evaluation is recommended already at early stage and focus on dysphagia, saliva aspiration, and oro-motor deficiencies. Clinical screening tools and diagnostics such as fiberoptic endoscopic evaluation of swallowing generate important data on therapy selection and control. Many cases profit from swallowing therapy programmes in order to activate compensation mechanisms as long compliances is given. In children with hypotonic oral muscles, oral stimulation plates can induce a relevant symptom release because of the improved lip closure. The pharmacologic treatment improved for pediatric cases as glycopyrrolate fluid solution (Sialanar (R)) is now indicated for hypersalivation within the E.U. The injection of botulinum toxin into the salivary glands has shown safe and effective results with long lasting saliva reduction. Here, a phase III trial is completed for Incobotulinum toxin A and, in the U.S., is indicated for the treatment of adult patients with chronic hypersalivation. Surgical treatment should be reserved for isolated cases. External radiation is judged as a safe and effective therapy when using modern 3D techniques to minimize tissue damage. Therapy effects and symptom severity has to be followed, especially in cases with underlying neurodegenerative disease.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Steffen, ArminUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jost, WolfgangUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Baeumer, TobiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Beutner, DirkUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Degenkolb-Weyers, SabineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gross, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grosheva, MariaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hakim, SamerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kahl, Kai G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Laskawi, RainerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lencer, RebekkaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Loehler, JanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Meyners, TheklaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rohrbach-Volland, SaskiaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schoenweiler, RainerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schroeder, Sara-ChristinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schroeder, SebastianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schroeter-Morasch, HeidrunUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schuster, MariaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Steinlechner, SusanneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Urban, RolandUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Guntinas-Lichius, OrlandoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-138325
DOI: 10.1055/a-0874-2406
Journal or Publication Title: Laryngo-Rhino-Otol.
Volume: 98
Number: 6
Page Range: S. 388 - 398
Date: 2019
Publisher: GEORG THIEME VERLAG KG
Place of Publication: STUTTGART
ISSN: 1438-8685
Language: German
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
BOTULINUM-TOXIN-A; SUBMANDIBULAR DUCT RELOCATION; FIBEROPTIC ENDOSCOPIC EVALUATION; AMYOTROPHIC-LATERAL-SCLEROSIS; GLYCOPYRROLATE ORAL SOLUTION; CEREBRAL-PALSY; DOUBLE-BLIND; SURGICAL-MANAGEMENT; RADIATION-THERAPY; NEUROLOGICAL DISORDERSMultiple languages
OtorhinolaryngologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/13832

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