Universität zu Köln

Chang, De-Hua, Slebocki, Karin, Khristenko, Ekaterina ORCID: 0000-0003-2611-5204, Herden, Jan, Salem, Johannes ORCID: 0000-0002-0528-9291, Hokamp, Nils Grosse, Mammadov, Kamal, Hellmich, Martin and Kabbasch, Christoph ORCID: 0000-0003-3712-2258 (2019). Low-dose computed tomography of urolithiasis in obese patients: a feasibility study to evaluate image reconstruction algorithms. Diabetes Metab. Syndr. Obes., 12. S. 439 - 446. ALBANY: DOVE MEDICAL PRESS LTD. ISSN 1178-7007

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Abstract

Purpose: Retrospective evaluation and comparison of image quality generated by low-dose computed tomography (LDCT) from obese patients with urolithiasis using alternative reconstruction algorithms. Materials and methods: Twenty-five obese patients (body mass index [BMI]>25 kg/m(2)) underwent LDCT scans for suspected urolithiasis. The scans were recompiled using filtered-back projection (FBP), statistical iterative reconstruction (iDose) and iterative model-based reconstruction (IMR). Dose-length product (DLP) and patient details were obtained from the CT dose report and clinical charts, respectively. Objective image noise was assessed by measuring the SD of Hounsfield units (HUs) in defined locations. Additionally, subjective image evaluation was independently performed by two radiologists using a 3-point Likert scale. The inter-reviewer agreement of image quality was calculated. Results: Ureteral concretions were observed in all CT scans, two of which revealed bilateral stones. The assessed patients' mean BMI was 29.29 +/- 3.74 kg/m(2), and the DLP of the CT scans was 100.04 +/- 10.00 mGy*cm. All scans were rated diagnostic with the iDose and iterative model-based reconstructions, whereas 41% of the scans performed with FBP reconstruction were nondiagnostic. With respect to image quality, IMR was superior to iDose and FBP, both in the objective (P<0.001) and overall subjective (P <= 0.008) evaluation of the respective data sets. The inter-reviewer agreement for overall image quality was almost perfect for IMR, substantial for iDose and moderate for FBP (kappa values of 1.0, 0.6 and 0.46, respectively). Conclusion: Using iterative image reconstruction algorithms, LDCT of urolithiasis is feasible in overweight patients with a BMI between 25 and 35 kg/m(2). Due to higher image quality, IMR is the preferred algorithm for scan reconstruction as it may help to avoid repeated examinations due to initial nondiagnostic scans.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Chang, De-Hua UNSPECIFIED UNSPECIFIED UNSPECIFIED Slebocki, Karin UNSPECIFIED UNSPECIFIED UNSPECIFIED Khristenko, Ekaterina UNSPECIFIED orcid.org/0000-0003-2611-5204 UNSPECIFIED Herden, Jan UNSPECIFIED UNSPECIFIED UNSPECIFIED Salem, Johannes UNSPECIFIED orcid.org/0000-0002-0528-9291 UNSPECIFIED Hokamp, Nils Grosse UNSPECIFIED UNSPECIFIED UNSPECIFIED Mammadov, Kamal UNSPECIFIED UNSPECIFIED UNSPECIFIED Hellmich, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Kabbasch, Christoph UNSPECIFIED orcid.org/0000-0003-3712-2258 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-139032
DOI:	10.2147/DMSO.S198641
Journal or Publication Title:	Diabetes Metab. Syndr. Obes.
Volume:	12
Page Range:	S. 439 - 446
Date:	2019
Publisher:	DOVE MEDICAL PRESS LTD
Place of Publication:	ALBANY
ISSN:	1178-7007
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language STATISTICAL ITERATIVE RECONSTRUCTION; TUBE CURRENT MODULATION; MULTIDETECTOR CT; FAMILY-HISTORY; UNITED-STATES; REDUCTION; PREVALENCE; QUALITY; STONES; OVERWEIGHT Multiple languages Endocrinology & Metabolism Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/13903