Universität zu Köln

Rudolph, Tanja K., Messika-Zeitoun, David, Frey, Norbert ORCID: 0000-0001-7611-378X, Lutz, Matthias, Krapf, Laura, Passefort, Stephanie, Fryearson, John, Simpson, Helen, Mortensen, Kai, Rehse, Sebastian, Tiroke, Andreas, Dodos, Fotini, Mies, Florian, Pohlmann, Christiane, Kurucova, Jana, Thoenes, Martin, Bramlage, Peter, Steeds, Richard Paul, Ahrens, Ingo and Kuhn, Andreas (2019). Caseload management and outcome of patients with aortic stenosis in primary/secondary versus tertiary care settings-design of the IMPULSE enhanced registry. Open Heart, 6 (2). LONDON: BMJ PUBLISHING GROUP. ISSN 2053-3624

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Abstract

Background Severe aortic stenosis (AS) is one of the most common and most serious valve diseases. Without timely intervention with surgical aortic valve replacement or transcatheter aortic valve replacement, patients have an estimated survival of 2-3 years. Guidelines for the treatment of AS have been developed, but studies suggest that as many as 42% of patients with AS are not treated according to these recommendations. The aims of this registry are to delineate the caseload of patients with AS, outline the management of these patients and determine appropriateness of treatments in participating centres with and without onsite access to surgery and percutaneous treatments. Methods/design The IMPULSE enhanced registry is an international, multicentre, prospective, observational cohort registry conducted at four central full access centres (tertiary care hospitals) and at least two satellite centres per hub (primary/secondary care hospitals). An estimated 800 patients will be enrolled in the registry and patient follow-up will last for 12 months. Discussion In addition to the primary aims determining the caseload management and outcome of patients with AS in primary, secondary and tertiary care settings, the registry will also determine a time course for the transition from asymptomatic to symptomatic status and the diagnostic steps, treatment decisions and the identification of decision-makers in tertiary versus primary/secondary care hospitals. The last patient will be enrolled in the registry in 2018 and results of the registry are anticipated in 2019.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Rudolph, Tanja K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Messika-Zeitoun, David UNSPECIFIED UNSPECIFIED UNSPECIFIED Frey, Norbert UNSPECIFIED orcid.org/0000-0001-7611-378X UNSPECIFIED Lutz, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Krapf, Laura UNSPECIFIED UNSPECIFIED UNSPECIFIED Passefort, Stephanie UNSPECIFIED UNSPECIFIED UNSPECIFIED Fryearson, John UNSPECIFIED UNSPECIFIED UNSPECIFIED Simpson, Helen UNSPECIFIED UNSPECIFIED UNSPECIFIED Mortensen, Kai UNSPECIFIED UNSPECIFIED UNSPECIFIED Rehse, Sebastian UNSPECIFIED UNSPECIFIED UNSPECIFIED Tiroke, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Dodos, Fotini UNSPECIFIED UNSPECIFIED UNSPECIFIED Mies, Florian UNSPECIFIED UNSPECIFIED UNSPECIFIED Pohlmann, Christiane UNSPECIFIED UNSPECIFIED UNSPECIFIED Kurucova, Jana UNSPECIFIED UNSPECIFIED UNSPECIFIED Thoenes, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Bramlage, Peter UNSPECIFIED UNSPECIFIED UNSPECIFIED Steeds, Richard Paul UNSPECIFIED UNSPECIFIED UNSPECIFIED Ahrens, Ingo UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuhn, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-141944
DOI:	10.1136/openhrt-2019-001019
Journal or Publication Title:	Open Heart
Volume:	6
Number:	2
Date:	2019
Publisher:	BMJ PUBLISHING GROUP
Place of Publication:	LONDON
ISSN:	2053-3624
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language VALVULAR HEART-DISEASE; VALVE-REPLACEMENT; ELDERLY-PATIENTS; TRANSCATHETER; IMPLANTATION; GUIDELINES; ADHERENCE; DIAGNOSIS; DECISION Multiple languages Cardiac & Cardiovascular Systems Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/14194