Brady, Marian C., Ali, Myzoon, VandenBerg, Kathryn, Williams, Linda J., Williams, Louise R., Abo, Masahiro, Becker, Frank, Bowen, Audrey ORCID: 0000-0003-4075-1215, Brandenburg, Caitlin, Breitenstein, Caterina, Bruehl, Stefanie, Copland, David A., Cranfill, Tamara B., di Pietro-Bachmann, Marie, Enderby, Pamela, Fillingham, Joanne, Galli, Federica Lucia, Gandolfi, Marialuisa ORCID: 0000-0002-0877-4807, Glize, Bertrand, Godecke, Erin, Hawkins, Neil, Hilari, Katerina ORCID: 0000-0003-2091-4849, Hinckley, Jacqueline, Horton, Simon, Howard, David, Jaecks, Petra, Jefferies, Elizabeth, Jesus, Luis M. T., Kambanaros, Maria, Kang, Eun Kyoung, Khedr, Eman M., Kong, Anthony Pak-Hin, Kukkonen, Tarja, Laganaro, Marina, Ralph, Matthew A. Lambon, Laska, Ann Charlotte, Leemann, Beatrice, Leff, Alexander P., Lima, Roxele R., Lorenz, Antje, MacWhinney, Brian, Marshall, Rebecca Shisler, Mattioli, Flavia, Mavis, Ilknur, Meinzer, Marcus, Nilipour, Reza, Noe, Enrique, Paik, Nam-Jong ORCID: 0000-0002-5193-8678, Palmer, Rebecca, Papathanasiou, Ilias, Patricio, Brigida F., Martins, Isabel Pavao, Price, Cathy, Jakovac, Tatjana Prizl, Rochon, Elizabeth, Rose, Miranda L., Rosso, Charlotte, Rubi-Fessen, Ilona ORCID: 0000-0002-9775-3812, Ruiter, Marina B. ORCID: 0000-0001-6147-5235, Snell, Claerwen, Stahl, Benjamin, Szaflarski, Jerzy P., Thomas, Shirley A., van de Sandt-Koenderman, Mieke, van der Meulen, Ineke, Visch-Brink, Evy, Worrall, Linda and Wright, Heather Harris (2020). RELEASE: a protocol for a systematic review based, individual participant data, meta- and network meta-analysis, of complex speech-language therapy interventions for stroke-related aphasia. Aphasiology, 34 (2). S. 137 - 158. ABINGDON: ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD. ISSN 1464-5041

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Abstract

Background: Speech and language therapy (SLT) benefits people with aphasia following stroke. Group level summary statistics from randomised controlled trials hinder exploration of highly complex SLT interventions and a clinically relevant heterogeneous population. Creating a database of individual participant data (IPD) for people with aphasia aims to allow exploration of individual and therapy-related predictors of recovery and prognosis. Aim: To explore the contribution that individual participant characteristics (including stroke and aphasia profiles) and SLT intervention components make to language recovery following stroke. Methods and procedures: We will identify eligible IPD datasets (including randomised controlled trials, non-randomised comparison studies, observational studies and registries) and invite their contribution to the database. Where possible, we will use meta- and network meta-analysis to explore language performance after stroke and predictors of recovery as it relates to participants who had no SLT, historical SLT or SLT in the primary research study. We will also examine the components of effective SLT interventions. Outcomes and results: Outcomes include changes in measures of functional communication, overall severity of language impairment, auditory comprehension, spoken language (including naming), reading and writing from baseline. Data captured on assessment tools will be collated and transformed to a standardised measure for each of the outcome domains. Conclusion: Our planned systematic-review-based IPD meta- and network meta-analysis is a large scale, international, multidisciplinary and methodologically complex endeavour. It will enable hypotheses to be generated and tested to optimise and inform development of interventions for people with aphasia after stroke. Systematic review registration: The protocol has been registered at the International Prospective Register of Systematic Reviews (PROSPERO; registration number: CRD42018110947)

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Brady, Marian C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ali, MyzoonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
VandenBerg, KathrynUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Williams, Linda J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Williams, Louise R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Abo, MasahiroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Becker, FrankUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bowen, AudreyUNSPECIFIEDorcid.org/0000-0003-4075-1215UNSPECIFIED
Brandenburg, CaitlinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Breitenstein, CaterinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bruehl, StefanieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Copland, David A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cranfill, Tamara B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
di Pietro-Bachmann, MarieUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Enderby, PamelaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fillingham, JoanneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Galli, Federica LuciaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gandolfi, MarialuisaUNSPECIFIEDorcid.org/0000-0002-0877-4807UNSPECIFIED
Glize, BertrandUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Godecke, ErinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hawkins, NeilUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hilari, KaterinaUNSPECIFIEDorcid.org/0000-0003-2091-4849UNSPECIFIED
Hinckley, JacquelineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Horton, SimonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Howard, DavidUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jaecks, PetraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jefferies, ElizabethUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jesus, Luis M. T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kambanaros, MariaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kang, Eun KyoungUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Khedr, Eman M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kong, Anthony Pak-HinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kukkonen, TarjaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Laganaro, MarinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ralph, Matthew A. LambonUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Laska, Ann CharlotteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Leemann, BeatriceUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Leff, Alexander P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lima, Roxele R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lorenz, AntjeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
MacWhinney, BrianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Marshall, Rebecca ShislerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mattioli, FlaviaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mavis, IlknurUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Meinzer, MarcusUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Nilipour, RezaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Noe, EnriqueUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Paik, Nam-JongUNSPECIFIEDorcid.org/0000-0002-5193-8678UNSPECIFIED
Palmer, RebeccaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Papathanasiou, IliasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Patricio, Brigida F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Martins, Isabel PavaoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Price, CathyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jakovac, Tatjana PrizlUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rochon, ElizabethUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rose, Miranda L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rosso, CharlotteUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rubi-Fessen, IlonaUNSPECIFIEDorcid.org/0000-0002-9775-3812UNSPECIFIED
Ruiter, Marina B.UNSPECIFIEDorcid.org/0000-0001-6147-5235UNSPECIFIED
Snell, ClaerwenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stahl, BenjaminUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Szaflarski, Jerzy P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thomas, Shirley A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van de Sandt-Koenderman, MiekeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van der Meulen, InekeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Visch-Brink, EvyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Worrall, LindaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wright, Heather HarrisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-143968
DOI: 10.1080/02687038.2019.1643003
Journal or Publication Title: Aphasiology
Volume: 34
Number: 2
Page Range: S. 137 - 158
Date: 2020
Publisher: ROUTLEDGE JOURNALS, TAYLOR & FRANCIS LTD
Place of Publication: ABINGDON
ISSN: 1464-5041
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
EXTENSION STATEMENT; INTENSITYMultiple languages
Audiology & Speech-Language Pathology; Linguistics; Clinical Neurology; RehabilitationMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/14396

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