Universität zu Köln

Laukamp, Kai Roman ORCID: 0000-0002-5600-5914, Gupta, Amit, Hokamp, Nils Grosse, Obmann, Verena Carola, Graner, Frank Philipp, Ho, Vivian, Ros, Pablo, Ramaiya, Nikhil and Gilkeson, Robert (2020). Role of spectral-detector CT in reduction of artifacts from contrast media in axillary and subclavian veins: single institution study in 50 patients. Acta Radiol., 61 (4). S. 450 - 461. LONDON: SAGE PUBLICATIONS LTD. ISSN 1600-0455

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Abstract

Background In CT imaging, a high concentration of iodinated contrast media in axillary and subclavian veins after brachial application can cause perivenous artifacts impairing diagnostic assessment of local vascular structures and soft tissue. Purpose To investigate reduction of perivenous hypo- and hyperattenuating artifacts of the axillary and subclavian veins using virtual monoenergetic images (VMI) in comparison to conventional CT images (CI), acquired on spectral-detector CT. Material and Methods 50 spectral-detector CT datasets of patients with perivenous artifacts from contrast media were included in this retrospective, institutional review board-approved study. CT images and virtual monoenergetic images (range 40-200 keV, 10-keV increments) were reconstructed from the same scans. Quantitative analysis was performed by region of interest-based assessment of mean attenuation (HU) and standard deviation in most pronounced hypo- and hyperdense artifacts and artifact-impaired arteries as well as muscle. Visually, artifact reduction, assessment of vessels, and surrounding soft tissue were rated on 5-point Likert-scales by two radiologists. Results In comparison to CT images, virtual monoenergetic images of >= 90 keV showed a significant reduction of hypo- and hyperattenuating artifacts (hypodense: CI -220.0 +/- 171.2 HU; VMI130keV -13.4 +/- 49.1 HU; hyperdense: CI 274.6 +/- 184.4 HU; VMI130keV 24.2 +/- 84.9 HU; P<0.001). Subjective analysis confirmed that virtual-monoenergetic images of >= 100 keV significantly reduced artifacts (hypodense: CI 2[1-3]; VMI130keV 5[4-5], hyperdense: CI 2[1-4]; VMI130keV 5[5-5], P<0.001) and improved diagnostic assessment. Best results for diagnostic assessment were noted for virtual monoenergetic images at 130 keV. Overcorrection of artifacts was observed at higher keV values. Interrater agreement was excellent for each evaluation and keV value (intraclass correlation coefficient 0.89). Conclusion Higher keV virtual monoenergetic images yielded significant reduction of contrast media artifacts and led to improved assessment of vessels and surrounding soft tissue. Recommended keV values for best diagnostic assessment are in the range of 100-160 keV.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Laukamp, Kai Roman UNSPECIFIED orcid.org/0000-0002-5600-5914 UNSPECIFIED Gupta, Amit UNSPECIFIED UNSPECIFIED UNSPECIFIED Hokamp, Nils Grosse UNSPECIFIED UNSPECIFIED UNSPECIFIED Obmann, Verena Carola UNSPECIFIED UNSPECIFIED UNSPECIFIED Graner, Frank Philipp UNSPECIFIED UNSPECIFIED UNSPECIFIED Ho, Vivian UNSPECIFIED UNSPECIFIED UNSPECIFIED Ros, Pablo UNSPECIFIED UNSPECIFIED UNSPECIFIED Ramaiya, Nikhil UNSPECIFIED UNSPECIFIED UNSPECIFIED Gilkeson, Robert UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-144155
DOI:	10.1177/0284185119868904
Journal or Publication Title:	Acta Radiol.
Volume:	61
Number:	4
Page Range:	S. 450 - 461
Date:	2020
Publisher:	SAGE PUBLICATIONS LTD
Place of Publication:	LONDON
ISSN:	1600-0455
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language DUAL-ENERGY CT; SALINE FLUSH; COEFFICIENT; PRINCIPLES; INJECTION Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/14415