Jordan, Jens, Fanciulli, Alessandra, Tank, Jens, Calandra-Buonaura, Giovanna, Cheshire, William P., Cortelli, Pietro, Eschlboeck, Sabine, Grassi, Guido, Hilz, Max J., Kaufmann, Horacio ORCID: 0000-0002-1851-9981, Lahrmann, Heinz, Mancia, Giuseppe, Mayer, Gert, Norcliffe-Kaufmann, Lucy, Pavy-Le Traon, Anne, Raj, Satish R., Robertson, David, Rocha, Isabel, Reuter, Hannes, Struhal, Walter, Thijs, Roland D., Tsioufis, Konstantinos P., van Dijk, J. Gert, Wenning, Gregor K. and Biaggioni, Italo (2019). Management of supine hypertension in patients with neurogenic orthostatic hypotension: scientific statement of the American Autonomic Society, European Federation of Autonomic Societies, and the European Society of Hypertension. J. Hypertens., 37 (8). S. 1541 - 1547. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1473-5598

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Abstract

Supine hypertension commonly occurs in patients with neurogenic orthostatic hypotension due to autonomic failure. Supine hypertension promotes nocturnal sodium excretion and orthostatic hypotension, thus, interfering with quality of life. Perusal of the literature on essential hypertension and smaller scale investigations in autonomic failure patients also suggest that supine hypertension may predispose to cardiovascular and renal disease. These reasons provide a rationale for treating supine hypertension. Yet, treatment of supine hypertension, be it through nonpharmacological or pharmacological approaches, may exacerbate orthostatic hypotension when patients get up during the night. Fall-related complications may occur. More research is needed to define the magnitude of the deleterious effects of supine hypertension on cardiovascular, cerebrovascular, and renal morbidity and mortality. Integration of more precise cardiovascular risk assessment, efficacy, and safety data, and the prognosis of the underlying condition causing autonomic failure is required for individualized management recommendations.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Jordan, JensUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fanciulli, AlessandraUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tank, JensUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Calandra-Buonaura, GiovannaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cheshire, William P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cortelli, PietroUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eschlboeck, SabineUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grassi, GuidoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hilz, Max J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kaufmann, HoracioUNSPECIFIEDorcid.org/0000-0002-1851-9981UNSPECIFIED
Lahrmann, HeinzUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mancia, GiuseppeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mayer, GertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Norcliffe-Kaufmann, LucyUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pavy-Le Traon, AnneUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Raj, Satish R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Robertson, DavidUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rocha, IsabelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Reuter, HannesUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Struhal, WalterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thijs, Roland D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tsioufis, Konstantinos P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van Dijk, J. GertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wenning, Gregor K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Biaggioni, ItaloUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-145508
DOI: 10.1097/HJH.0000000000002078
Journal or Publication Title: J. Hypertens.
Volume: 37
Number: 8
Page Range: S. 1541 - 1547
Date: 2019
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Place of Publication: PHILADELPHIA
ISSN: 1473-5598
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
BLOOD-PRESSURE; ANGIOTENSIN-II; FAILURE; ASSOCIATION; CLONIDINE; MIDODRINE; EFFICACY; BALANCE; PLACEBOMultiple languages
Peripheral Vascular DiseaseMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/14550

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