Alegiani, Anna C., Dorn, Franziska ORCID: 0000-0001-9093-8307, Herzberg, Moriz, Wollenweber, Frank A., Kellert, Lars, Siebert, Eberhard ORCID: 0000-0001-7395-6546, Nolte, Christian H., von Rennenberg, Regina, Hattingen, Elke ORCID: 0000-0002-8392-9004, Petzold, Gabor C., Bode, Felix J., Pfeilschifter, Waltraud, Schaefer, Jan H., Wagner, Marlies, Roether, Joachim, Eckert, Bernd, Kraft, Peter, Pham, Mirko, Boeckh-Behrens, Tobias, Wunderlich, Silke, Bernkopf, Kathleen, Reich, Arno, Wiesmann, Martin, Mpotsaris, Anastasios ORCID: 0000-0002-1275-8164, Psychogios, Marios, Liman, Jan, Maier, Ilko, Berrouschot, Joerg, Bormann, Albrecht, Limmroth, Volker, Spreer, Joachim, Petersen, Martina, Krause, Lars, Lowens, Stephan, Kraemer, Christoffer, Zweynert, Sarah, Lange, Kristin S., Thonke, Sven, Kastrup, Andreas, Papanagiotou, Panagiotis, Alber, Burkhard, Braun, Michael, Fiehler, Jens, Gerloff, Christian, Dichgans, Martin and Thomalla, Goetz (2019). Systematic evaluation of stroke thrombectomy in clinical practice: The German Stroke Registry Endovascular Treatment. Int. J. Stroke, 14 (4). S. 372 - 381. LONDON: SAGE PUBLICATIONS LTD. ISSN 1747-4949

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Abstract

Background: Endovascular treatment has become standard of care for the treatment of acute ischemic stroke with large vessel occlusion. However, patients treated in clinical practice differ from the selected populations randomized in clinical trials. Aims: The German Stroke Registry Endovascular Treatment (GSR-ET) aims at a systematic evaluation of outcome, safety, and process parameters of endovascular stroke treatment in standard of care in Germany. Methods: The GSR-ET is an academic, independent, prospective, multicenter, observational registry study. Participating stroke centers from all over of Germany consecutively enroll patients transferred to the angiography suite with an intention to be treated with endovascular stroke treatment. Patients receive regular care. Data are collected as part of clinical routine. Baseline clinical and procedural information and clinical follow-up information after 90 days are recorded. Here, we present an analysis of baseline data of the first 1662 patients included in the GSR-ET. Results: The registry was established in June 2015. By 31 December 2017, 1662 patients were enrolled in 23 active sites. Mean age was 72 +/- 13 years, 50% were female, and median National Institutes of Health Stroke Scale on admission was 15 (IQR 10-19), 88% had anterior circulation occlusion. Median ASPECT score was 8 (IQR 7-10) prior to intervention. Fifty-nine percent of patients received intravenous thrombolysis prior to thrombectomy. Mean onset-to-groin time was 224 +/- 176 min. Conclusions: Baseline characteristics of stroke patients undergoing thrombectomy in clinical practice differ from those in the randomized trials. The GSR-ET will provide valuable insights into practices of endovascular treatment in routine care of acute ischemic stroke.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Alegiani, Anna C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dorn, FranziskaUNSPECIFIEDorcid.org/0000-0001-9093-8307UNSPECIFIED
Herzberg, MorizUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wollenweber, Frank A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kellert, LarsUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Siebert, EberhardUNSPECIFIEDorcid.org/0000-0001-7395-6546UNSPECIFIED
Nolte, Christian H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
von Rennenberg, ReginaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hattingen, ElkeUNSPECIFIEDorcid.org/0000-0002-8392-9004UNSPECIFIED
Petzold, Gabor C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bode, Felix J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pfeilschifter, WaltraudUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schaefer, Jan H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wagner, MarliesUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Roether, JoachimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eckert, BerndUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kraft, PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pham, MirkoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Boeckh-Behrens, TobiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wunderlich, SilkeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bernkopf, KathleenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Reich, ArnoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wiesmann, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mpotsaris, AnastasiosUNSPECIFIEDorcid.org/0000-0002-1275-8164UNSPECIFIED
Psychogios, MariosUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Liman, JanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Maier, IlkoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Berrouschot, JoergUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bormann, AlbrechtUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Limmroth, VolkerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Spreer, JoachimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Petersen, MartinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Krause, LarsUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lowens, StephanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kraemer, ChristofferUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zweynert, SarahUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lange, Kristin S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thonke, SvenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kastrup, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Papanagiotou, PanagiotisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Alber, BurkhardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Braun, MichaelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fiehler, JensUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gerloff, ChristianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dichgans, MartinUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Thomalla, GoetzUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-146309
DOI: 10.1177/1747493018806199
Journal or Publication Title: Int. J. Stroke
Volume: 14
Number: 4
Page Range: S. 372 - 381
Date: 2019
Publisher: SAGE PUBLICATIONS LTD
Place of Publication: LONDON
ISSN: 1747-4949
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
ACUTE ISCHEMIC-STROKE; ANTERIOR CIRCULATION STROKE; MECHANICAL THROMBECTOMY; CARE; THROMBOLYSIS; REPERFUSION; OUTCOMES; TRIAL; TIME; AGEMultiple languages
Clinical Neurology; Peripheral Vascular DiseaseMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/14630

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