Universität zu Köln

Parganlija, Dajana, Nieberg, Vita, Sauer, Marc, Rittweger, Joern, Bloch, Wilhelm and Zange, Jochen (2019). Lower body negative pressure enhances oxygen availability in the knee extensor muscles during intense resistive exercise in supine position. Eur. J. Appl. Physiol., 119 (6). S. 1289 - 1304. NEW YORK: SPRINGER. ISSN 1439-6327

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Abstract

PurposeDuring exercise in supine posture or under microgravity in space, the gravity-dependent component of local blood pressure in leg muscles at upright posture can be simulated by lower body negative pressure (LBNP). We hypothesized that during resistive exercise LBNP favors oxygen availability in lower extremities, benefiting energy levels and performance of working muscles.MethodsIn permutated crossover design, nine subjects performed a series of fifteen slow-paced concentric (4s) and eccentric contractions (4s) without or with 40mmHg LBNP and 4s pause between repetitions. The force at knee flexion was 6% of the one repetition maximum (1-RM) and gradually increased to 60% 1RM in the first half of the individual range of motion, subsequently remaining constant until full extension.ResultsDuring the low force periods of continuous exercise, LBNP enhanced the refill of capillary blood measured by near infrared spectroscopy, amplifying the increase of total haemoglobin by about 20 mu mol/l (p<0.01) and oxyhaemoglobin by about 10 mu mol/l (p<0.01). During continuous exercise, LBNP induced a trend towards a lower EMG increment. This LBNP effect was not found when the periods of low forces at knee flexion were extended by 4s pauses. Increased respiratory oxygen uptake (+0.1l/min, p<0.05) indicated overall enhanced muscle energy turn-over.ConclusionsOur results suggest stimulation of oxidative metabolism through LBNP enables working muscles to meet the energy demands of intense exercise. Further research is needed on the consequences for energy metabolism and the molecular control of growth and differentiation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Parganlija, Dajana UNSPECIFIED UNSPECIFIED UNSPECIFIED Nieberg, Vita UNSPECIFIED UNSPECIFIED UNSPECIFIED Sauer, Marc UNSPECIFIED UNSPECIFIED UNSPECIFIED Rittweger, Joern UNSPECIFIED UNSPECIFIED UNSPECIFIED Bloch, Wilhelm UNSPECIFIED UNSPECIFIED UNSPECIFIED Zange, Jochen UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-147208
DOI:	10.1007/s00421-019-04113-w
Journal or Publication Title:	Eur. J. Appl. Physiol.
Volume:	119
Number:	6
Page Range:	S. 1289 - 1304
Date:	2019
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1439-6327
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language BLOOD-FLOW; SKELETAL-MUSCLE; PUMP FUNCTION; CALF MUSCLE; UPRIGHT; COUNTERMEASURE; METABOLISM; LOCOMOTION; RESPONSES; SPEED Multiple languages Physiology; Sport Sciences Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/14720