Universität zu Köln

Djordjevic, Ilija ORCID: 0000-0002-5810-8626, Sabashnikov, Anton, Deppe, A. C., Kuhn, E., Eghbalzadeh, K., Merkle, J., Maier, J., Weber, C., Azizov, F., Sindhu, D. and Wahlers, T. (2019). Risk factors associated with 30-day mortality for out-of-center ECMO support: experience from the newly launched ECMO retrieval service. J. Artif. Organs, 22 (2). S. 110 - 118. TOKYO: SPRINGER JAPAN KK. ISSN 1619-0904

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Abstract

Out-of-hospital extracorporeal membrane oxygenation (ECMO) implantation and ECMO transport have become a growing field useful for emergent treatment of heart or lung failure with increasing number of centers launching such service. This study was designed to present risk factors predicting 30-day mortality for patients receiving ECMO support in a newly launched ECMO retrieval service. From 01/2015 till 01/2017 28 consecutive patients received ECMO support in peripheral hospitals using a miniaturized portable Cardiohelp System((R)) (Maquet, Rastatt Germany) for heart, lung or heart/lung failure as a bridge-to-decision as a part of our newly launched ECMO retrieval service. Outcomes and predictors for 30-day mortality were presented. The mean age was 56 +/- 15 (maximum 78) years. The mean ECMO support duration was 97 +/- 100h, whereas 11 patients (40%) were weaned off support and discharged from hospital. Presence of hemolysis (p=0.041), renal failure (p=0.016), lower platelet count before ECMO implantation (p=0.001), and higher lactate 24h after initiation of support (p=0.006) were factors associated with 30-day mortality. Initial success of an ECMO retrieval service depends on logistic organization and clinical management. Taking into consideration highly deleterious effects of hemodynamic malperfusion of end organs, rapid initiation of ECMO support is a vital factor for survival. This is highlighted by predictive factors of early mortality that are associated with peripheral organ failure or complications.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Djordjevic, Ilija UNSPECIFIED orcid.org/0000-0002-5810-8626 UNSPECIFIED Sabashnikov, Anton UNSPECIFIED UNSPECIFIED UNSPECIFIED Deppe, A. C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuhn, E. UNSPECIFIED UNSPECIFIED UNSPECIFIED Eghbalzadeh, K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Merkle, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Maier, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Weber, C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Azizov, F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sindhu, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wahlers, T. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-147582
DOI:	10.1007/s10047-019-01092-9
Journal or Publication Title:	J. Artif. Organs
Volume:	22
Number:	2
Page Range:	S. 110 - 118
Date:	2019
Publisher:	SPRINGER JAPAN KK
Place of Publication:	TOKYO
ISSN:	1619-0904
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language EXTRACORPOREAL MEMBRANE-OXYGENATION; CARDIOPULMONARY-RESUSCITATION; LIFE-SUPPORT; TIME; THERAPY; RESCUE; DEVICE Multiple languages Engineering, Biomedical; Transplantation Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/14758