Universität zu Köln

Kabbasch, Christoph, Goertz, Lukas, Siebert, Eberhard, Herzberg, Moriz, Borggrefe, Jan ORCID: 0000-0003-2908-7560, Dorn, Franziska ORCID: 0000-0001-9093-8307 and Liebig, Thomas (2019). Factors that determine aneurysm occlusion after embolization with the Woven EndoBridge (WEB). J. NeuroInterventional Surg., 11 (5). S. 503 - 511. LONDON: BMJ PUBLISHING GROUP. ISSN 1759-8486

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Abstract

Background The Woven EndoBridge (WEB) device is a novel endovascular tool for the treatment of wide-necked intracranial aneurysms. Objective To evaluate factors influencing aneurysm occlusion and aneurysm recurrence after WEB embolization. Methods A total of 113 patients (mean age 58.9 +/- 11.9 years) with 114 aneurysms (mean size 8.6 +/- 4.6 mm) were successfully treated with the WEB device at three German tertiary care centers between May 2011 and February 2018. Aneurysm occlusion was evaluated using the Raymond-Roy occlusion classification. We retrospectively collected patient characteristics, anatomical details, and procedural aspects and evaluated their impact on aneurysm occlusion and recurrence. Results Of 98 patients available for a 6-month angiographic follow-up, complete occlusion was achieved in 62.2%, neck remnants in 21.4%, and aneurysm remnants in 16.3%. Aneurysm recurrence occurred in 15.3%. Initial partial aneurysm thrombosis, recurrent aneurysms, aneurysm size, and simultaneous treatment by WEB and coil were associated with aneurysm remnants (p<0.05). Initial partial aneurysm thrombosis, increasing aneurysm size, and treatment by WEB and coil also predicted aneurysm recurrence (p<0.05). In the subgroup analysis of 71 aneurysms treated with WEB only, initial incomplete occlusion and male sex were associated with aneurysm remnants (p<0.05), while aneurysm height correlated with aneurysm recurrence (p=0.008). Conclusions The WEB provides a high rate of adequate occlusion even in a subset of complex wide-necked intracranial aneurysms. Anatomic results tend to be less favourable in large and partially thrombosed aneurysms and after treatment with WEB and coil.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kabbasch, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Goertz, Lukas UNSPECIFIED UNSPECIFIED UNSPECIFIED Siebert, Eberhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Herzberg, Moriz UNSPECIFIED UNSPECIFIED UNSPECIFIED Borggrefe, Jan UNSPECIFIED orcid.org/0000-0003-2908-7560 UNSPECIFIED Dorn, Franziska UNSPECIFIED orcid.org/0000-0001-9093-8307 UNSPECIFIED Liebig, Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-148935
DOI:	10.1136/neurintsurg-2018-014361
Journal or Publication Title:	J. NeuroInterventional Surg.
Volume:	11
Number:	5
Page Range:	S. 503 - 511
Date:	2019
Publisher:	BMJ PUBLISHING GROUP
Place of Publication:	LONDON
ISSN:	1759-8486
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language THROMBOSED INTRACRANIAL ANEURYSMS; ENDOVASCULAR TREATMENT; CEREBRAL ANEURYSMS; FLOW DISRUPTION; DEVICE; FEASIBILITY; RECURRENCES; PREDICTORS; EXPERIENCE; THERAPY Multiple languages Neuroimaging; Surgery Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/14893