Universität zu Köln

Schroeder, Daniel C., Maul, Alexandra C., Guschlbauer, Maria, Finke, Simon-Richard, Bethencourt, David de la Puente, Neumann, Tobias, Padosch, Stephan A., Annecke, Thorsten ORCID: 0000-0002-2496-4432, Boettiger, Bernd W., Sterner-Kock, Anja and Herff, Holger (2019). Esophageal Heat Exchanger Versus Water-Circulating Cooling Blanket for Targeted Temperature Management. Ther. Hypothermia Temp. Manag., 9 (4). S. 251 - 258. NEW ROCHELLE: MARY ANN LIEBERT, INC. ISSN 2153-7933

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Abstract

To date, the optimal cooling device for targeted temperature management (TTM) remains unclear. Water-circulating cooling blankets are broadly available and quickly applied but reveal inaccuracy during maintenance and rewarming period. Recently, esophageal heat exchangers (EHEs) have been shown to be easily inserted, revealed effective cooling rates (0.26-1.12 degrees C/h), acceptable deviations from target core temperature (<0.5 degrees C), and rewarming rates between 0.2 and 0.4 degrees C/h. The aim of this study was to compare cooling rates, accuracy during maintenance, and rewarming period as well as side effects of EHEs with water-circulating cooling blankets in a porcine TTM model. Mean core temperature of domestic pigs (n = 16) weighing 83.2 +/- 3.6 kg was decreased to a target core temperature of 33 degrees C by either using EHEs or water-circulating cooling blankets. After 8 hours of maintenance, rewarming was started at a goal rate of 0.25 degrees C/h. Mean cooling rates were 1.3 +/- 0.1 degrees C/h (EHE) and 3.2 +/- 0.5 degrees C/h (blanket, p < 0.0002). Mean difference to target core temperature during maintenance ranged between +/- 1 degrees C. Mean rewarming rates were 0.21 +/- 0.01 degrees C/h (EHE) and 0.22 +/- 0.02 degrees C/h (blanket, n.s.). There were no differences with regard to side effects such as brady- or tachycardia, hypo- or hyperkalemia, hypo- or hyperglycemia, hypotension, shivering, or esophageal tissue damage. Target temperature can be achieved faster by water-circulating cooling blankets. EHEs and water-circulating cooling blankets were demonstrated to be reliable and safe cooling devices in a prolonged porcine TTM model with more variability in EHE group.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schroeder, Daniel C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Maul, Alexandra C. UNSPECIFIED UNSPECIFIED UNSPECIFIED Guschlbauer, Maria UNSPECIFIED UNSPECIFIED UNSPECIFIED Finke, Simon-Richard UNSPECIFIED UNSPECIFIED UNSPECIFIED Bethencourt, David de la Puente UNSPECIFIED UNSPECIFIED UNSPECIFIED Neumann, Tobias UNSPECIFIED UNSPECIFIED UNSPECIFIED Padosch, Stephan A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Annecke, Thorsten UNSPECIFIED orcid.org/0000-0002-2496-4432 UNSPECIFIED Boettiger, Bernd W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Sterner-Kock, Anja UNSPECIFIED UNSPECIFIED UNSPECIFIED Herff, Holger UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-153550
DOI:	10.1089/ther.2018.0054
Journal or Publication Title:	Ther. Hypothermia Temp. Manag.
Volume:	9
Number:	4
Page Range:	S. 251 - 258
Date:	2019
Publisher:	MARY ANN LIEBERT, INC
Place of Publication:	NEW ROCHELLE
ISSN:	2153-7933
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language HOSPITAL CARDIAC-ARREST; THERAPEUTIC HYPOTHERMIA; DEVICE; INDUCTION; RESUSCITATION; NORMOTHERMIA; FEASIBILITY; IMPACT Multiple languages Critical Care Medicine Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/15355