Kovacs, Gabor, Dumitrescu, Daniel, Barner, Andreas, Greiner, Sebastian, Gruenig, Ekkehard, Hager, Alfred ORCID: 0000-0002-2481-2017, Koehler, Thomas, Kozlik-Feldmann, Rainer, Kruck, Irmtraut, Lammers, Astrid E., Mereles, Derliz ORCID: 0000-0001-9601-7103, Meyer, Andreas, Meyer, Joachim, Pabst, Stefan, Seyfarth, Hans-Juergen, Sinning, Christoph, Sorichter, Stephan, Staehler, Gerd, Wilkens, Heinrike ORCID: 0000-0002-7789-8563 and Held, Matthias (2018). Definition, clinical classification and initial diagnosis of pulmonary hypertension: Updated recommendations from the Cologne Consensus Conference 2018. Int. J. Cardiol., 272. S. 11 - 20. CLARE: ELSEVIER IRELAND LTD. ISSN 1874-1754

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Abstract

In the summer of 2016, delegates from the German Society of Cardiology (DGK), the German Respiratory Society (DGP), and the German Society of Pediatric Cardiology (DGPK) met in Cologne, Germany, to define consensus-based practice recommendations for the management of patients with pulmonary hypertension (PH). These recommendations were built on the 2015 European Pulmonary Hypertension guidelines, aiming at their practical implementation, considering country-specific issues, and including new evidence, where available. To this end, a number of working groups was initiated, one of which was specifically dedicated to the definition, clinical classification and initial diagnosis of PH. While the European guidelines provide a detailed clinical classification and a structured approach for diagnostic testing, their application in routine care may be challenging, particularly given the changing phenotype of PH patients who are nowadays often elderly and may present with multiple potential causes of PH, as well as comorbid conditions. Specifically, the working group addresses the thoroughness of diagnostic testing, and the roles of echocardiography, exercise testing, and genetic testing in diagnosing PH. Furthermore, challenges in the diagnostic work-up of patients with various causes of PH including PAH with comorbidities, CTEPH and coexisting conditions are highlighted, and a modified diagnostic algorithm is provided. The detailed results and recommendations of the working group on definition, clinical classification and initial diagnosis of PH, which were last updated in the spring of 2018, are summarized in this article. (c) 2018 Published by Elsevier B.V.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Kovacs, GaborUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Dumitrescu, DanielUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Barner, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Greiner, SebastianUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gruenig, EkkehardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hager, AlfredUNSPECIFIEDorcid.org/0000-0002-2481-2017UNSPECIFIED
Koehler, ThomasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kozlik-Feldmann, RainerUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kruck, IrmtrautUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lammers, Astrid E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mereles, DerlizUNSPECIFIEDorcid.org/0000-0001-9601-7103UNSPECIFIED
Meyer, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Meyer, JoachimUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pabst, StefanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Seyfarth, Hans-JuergenUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sinning, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sorichter, StephanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Staehler, GerdUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wilkens, HeinrikeUNSPECIFIEDorcid.org/0000-0002-7789-8563UNSPECIFIED
Held, MatthiasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-162543
DOI: 10.1016/j.ijcard.2018.08.083
Journal or Publication Title: Int. J. Cardiol.
Volume: 272
Page Range: S. 11 - 20
Date: 2018
Publisher: ELSEVIER IRELAND LTD
Place of Publication: CLARE
ISSN: 1874-1754
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
RIGHT HEART CATHETERIZATION; ARTERY PRESSURE RESPONSE; SYSTEMIC-SCLEROSIS; COMPUTED-TOMOGRAPHY; PROGNOSTIC VALUE; DOPPLER-ECHOCARDIOGRAPHY; REFERENCE VALUES; EXERCISE; HEMODYNAMICS; BIOMARKERSMultiple languages
Cardiac & Cardiovascular SystemsMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/16254

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