Universität zu Köln

Laban, S., Doescher, J., Busch, C. -J., Wollenberg, B., Dietz, A., Wuerdemann, N., Schuler, P. J. and Hoffmann, T. K. (2018). Immunotherapy highlights of the ASCO annual meeting 2018 for head and neck cancers. HNO, 66 (12). S. 880 - 888. NEW YORK: SPRINGER. ISSN 1433-0458

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Abstract

Background. Immunotherapeutic strategies are becoming increasinglymore important for head and neck cancer and numerous clinical trials were presented at the annual meeting of the American Society of Clinical Oncology (ASCO) 2018. Objective. In this review the most interesting clinical trials and trial results for immunotherapy of head and neck cancer are summarized. Material and methods. All abstracts and presentations on immunotherapy of head and neck cancer at the annual meeting of the ASCO 2018 were screened to select the most interesting trials for a more detailed analysis. Results. For head and neck cancer, practice changing phase III trial results were missing, but several noteworthy new strategies and trial results for immunotherapy were presented. Neoadjuvant immunotherapy trials, results concerning immunotherapy in old age, prognostic implications of immune-mediated adverse events and new immunotherapy combinations are summarized in this article. Conclusion. The role of immunotherapy for the treatment of head and neck cancer is markedly increasing. Many pioneering trials are currently ongoing, in the phase of data analysis or in planning.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Laban, S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Doescher, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Busch, C. -J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wollenberg, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Dietz, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wuerdemann, N. UNSPECIFIED UNSPECIFIED UNSPECIFIED Schuler, P. J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Hoffmann, T. K. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-163819
DOI:	10.1007/s00106-018-0586-2
Journal or Publication Title:	HNO
Volume:	66
Number:	12
Page Range:	S. 880 - 888
Date:	2018
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1433-0458
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SQUAMOUS-CELL CARCINOMA; SURGICAL COMPLICATIONS; RECURRENT; CLASSIFICATION; NIVOLUMAB Multiple languages Otorhinolaryngology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/16381