Universität zu Köln

Maus, Volker, Behme, Daniel, Kabbasch, Christoph, Borggrefe, Jan ORCID: 0000-0003-2908-7560, Tsogkas, Ioannis, Nikoubashman, Omid, Wiesmann, Martin, Knauth, Michael, Mpotsaris, Anastasios ORCID: 0000-0002-1275-8164 and Psychogios, Marios Nikos (2018). Maximizing First-Pass Complete Reperfusion with SAVE. Clin. Neuroradiol., 28 (3). S. 327 - 339. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1869-1447

Full text not available from this repository.

Abstract

Background Endovascular techniques for treatment of large vessel occlusions (LVO) in patients with acute ischemic stroke (AIS) have advanced in recent years. We report a multicenter experience using a combined aspiration and stent retriever technique for mechanical thrombectomy (MT). Methods We retrospectively analyzed 32 consecutive MT patients using a novel, combined approach of Stent retriever Assisted Vacuum-locked Extraction (SAVE) by 3 operators at 3 stroke centers. Primary endpoint was successful firstpass reperfusion with a modified Thrombolysis in Cerebral Infarction (mTICI) score of 3. Secondary endpoints were number of passes, time from groin puncture to reperfusion, embolization to new territories (ENT), postinterventional symptomatic intracranial hemorrhage (sICH) and clinical outcome at discharge. Results First-pass mTICI 3 reperfusion was achieved in 23 out of 32 patients (72%) with a mean groin puncture to reperfusion time of 36.0min +/- 15.8 and mTICI 3 was accomplished in 25 out of 32 cases (78%) with a maximum of 3 attempts. Successful reperfusion (mTICI = 2b) was achieved in all patients (100%) with a mean time from groin puncture to reperfusion of 44.5min +/- 25.8 and an average of 1.2 +/- 0.7 attempts. The rate of ENT was 0% and 1 patient with sICH after MT died on postoperative day 4. At discharge, the median National Institutes of Health Stroke Scale (NIHSS) score was 4 (range 0-17) and favorable neurological outcome by the modified Rankin score (mRS <= 2) was achieved in 19 out of 32 patients (59%). Conclusion SAVE is fast and appears to be very effective in terms of first-pass complete reperfusion in patients with LVO.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Maus, Volker UNSPECIFIED UNSPECIFIED UNSPECIFIED Behme, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Kabbasch, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED Borggrefe, Jan UNSPECIFIED orcid.org/0000-0003-2908-7560 UNSPECIFIED Tsogkas, Ioannis UNSPECIFIED UNSPECIFIED UNSPECIFIED Nikoubashman, Omid UNSPECIFIED UNSPECIFIED UNSPECIFIED Wiesmann, Martin UNSPECIFIED UNSPECIFIED UNSPECIFIED Knauth, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Mpotsaris, Anastasios UNSPECIFIED orcid.org/0000-0002-1275-8164 UNSPECIFIED Psychogios, Marios Nikos UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-173547
DOI:	10.1007/s00062-017-0566-z
Journal or Publication Title:	Clin. Neuroradiol.
Volume:	28
Number:	3
Page Range:	S. 327 - 339
Date:	2018
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1869-1447
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ACUTE ISCHEMIC-STROKE; STENT-RETRIEVER THROMBECTOMY; BALLOON GUIDE CATHETER; 1ST PASS TECHNIQUE; INTRAVENOUS T-PA; MECHANICAL THROMBECTOMY; ENDOVASCULAR TREATMENT; INTRAARTERIAL TREATMENT; CLINICAL-OUTCOMES; RANDOMIZED-TRIAL Multiple languages Clinical Neurology; Radiology, Nuclear Medicine & Medical Imaging Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/17354