Universität zu Köln

Vermoehlen, Vanessa, Schiller, Petra, Schickendantz, Sabine, Drache, Marion, Hussack, Sabine, Gerber-Grote, Andreas ORCID: 0000-0003-2157-4065 and Poehlau, Dieter (2018). Hippotherapy for patients with multiple sclerosis: A multicenter randomized controlled trial (MS-HIPPO). Mult. Scler. J., 24 (10). S. 1375 - 1383. LONDON: SAGE PUBLICATIONS LTD. ISSN 1477-0970

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Abstract

Background: Evidence-based complementary treatment options for multiple sclerosis (MS) are limited. Objective: To investigate the effect of hippotherapy plus standard care versus standard care alone in MS patients. Methods: A total of 70 adults with MS were recruited in five German centers and randomly allocated to the intervention group (12weeks of hippotherapy) or the control group. Primary outcome was the change in the Berg Balance Scale (BBS) after 12weeks, and further outcome measures included fatigue, pain, quality of life, and spasticity. Results: Covariance analysis of the primary endpoint resulted in a mean difference in BBS change of 2.33 (95% confidence interval (CI): 0.03-4.63, p=0.047) between intervention (n=32) and control (n=38) groups. Benefit on BBS was largest for the subgroup with an Expanded Disability Status Scale (EDSS)5 (5.1, p=0.001). Fatigue (-6.8, p=0.02) and spasticity (-0.9, p=0.03) improved in the intervention group. The mean difference in change between groups was 12.0 (p<0.001) in physical health score and 14.4 (p<0.001) in mental health score of Multiple Sclerosis Quality of Life-54 (MSQoL-54). Conclusion: Hippotherapy plus standard care, while below the threshold of a minimal clinically important difference, significantly improved balance and also fatigue, spasticity, and quality of life in MS patients.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Vermoehlen, Vanessa UNSPECIFIED UNSPECIFIED UNSPECIFIED Schiller, Petra UNSPECIFIED UNSPECIFIED UNSPECIFIED Schickendantz, Sabine UNSPECIFIED UNSPECIFIED UNSPECIFIED Drache, Marion UNSPECIFIED UNSPECIFIED UNSPECIFIED Hussack, Sabine UNSPECIFIED UNSPECIFIED UNSPECIFIED Gerber-Grote, Andreas UNSPECIFIED orcid.org/0000-0003-2157-4065 UNSPECIFIED Poehlau, Dieter UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-175463
DOI:	10.1177/1352458517721354
Journal or Publication Title:	Mult. Scler. J.
Volume:	24
Number:	10
Page Range:	S. 1375 - 1383
Date:	2018
Publisher:	SAGE PUBLICATIONS LTD
Place of Publication:	LONDON
ISSN:	1477-0970
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language QUALITY-OF-LIFE; SYMPTOMATIC TREATMENT; BALANCE SCALE; RELIABILITY; PAIN Multiple languages Clinical Neurology; Neurosciences Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/17546