Bousquet, J., Devillier, P., Anto, J. M., Bewick, M., Haahtela, T., Arnavielhe, S., Bedbrook, A., Murray, R., van Eerd, M., Fonseca, J. A., Morais Almeida, M., Todo Bom, A., Menditto, E., Passalacqua, G., Stellato, C., Triggiani, M., Ventura, M. T., Vezzani, G., Annesi-Maesano, I., Bourret, R., Bosse, I., Caimmi, D., Cartier, C., Demoly, P., Just, J., Portejoie, F., Siroux, V., Viart, F., Bergmann, K. C., Keil, T., Klimek, L., Moesges, R., Pfaar, O., Shamai, S., Zuberbier, T., Mullol, J., Valero, A., Spranger, O., Tomazic, P. V., Kowalski, M. L., Kuna, P., Kupczyk, M., Raciborski, F., Samolinski, B., Toppila-Salmi, S. K., Valovirta, E., Cruz, A. A., Sarquis-Serpa, F., da Silva, J., Stelmach, R., Larenas-Linnemann, D., Rodriguez Gonzalez, M., Burguete Cabanas, M. T., Kvedariene, V., Valiulis, A., Chavannes, N. H., Fokkens, W. J., Ryan, D., Sheikh, A., Bachert, C., Hellings, P. W., VandenPlas, O., Ballardini, N., Kull, I., Melen, E., Westman, M., Wickman, M., Bindslev-Jensen, C., Eller, E., Bosnic-Anticevich, S., O'Hehir, R. E., Agache, I., Bieber, T., Casale, T., Gemicioglu, B., Ivancevich, J. C., De Vries, G., Sorensen, M., Yorgancioglu, A. and Laune, D. (2018). Daily allergic multimorbidity in rhinitis using mobile technology: A novel concept of the MASK study. Allergy, 73 (8). S. 1622 - 1632. HOBOKEN: WILEY. ISSN 1398-9995

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Abstract

BackgroundMultimorbidity in allergic airway diseases is well known, but no data exist about the daily dynamics of symptoms and their impact on work. To better understand this, we aimed to assess the presence and control of daily allergic multimorbidity (asthma, conjunctivitis, rhinitis) and its impact on work productivity using a mobile technology, the Allergy Diary. MethodsWe undertook a 1-year prospective observational study in which 4 210 users and 32585days were monitored in 19 countries. Five visual analogue scales (VAS) assessed the daily burden of the disease (i.e., global evaluation, nose, eyes, asthma and work). Visual analogue scale levels <20/100 were categorized as Low burden and VAS levels 50/100 as High burden. ResultsVisual analogue scales global measured levels assessing the global control of the allergic disease were significantly associated with allergic multimorbidity. Eight hypothesis-driven patterns were defined based on Low and High VAS levels. There were <0.2% days of Rhinitis Low and Asthma High or Conjunctivitis High patterns. There were 5.9% days with a Rhinitis HighAsthma Low pattern. There were 1.7% days with a Rhinitis HighAsthma HighConjunctivitis Lowpattern. A novel Rhinitis HighAsthma HighConjunctivitis High pattern was identified in 2.9% days and had the greatest impact on uncontrolled VAS global measured and impaired work productivity. Work productivity was significantly correlated with VAS global measured levels. ConclusionsIn a novel approach examining daily symptoms with mobile technology, we found considerable intra-individual variability of allergic multimorbidity including a previously unrecognized extreme pattern of uncontrolled multimorbidity.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Bousquet, J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Devillier, P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Anto, J. M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bewick, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Haahtela, T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Arnavielhe, S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bedbrook, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Murray, R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
van Eerd, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fonseca, J. A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Morais Almeida, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Todo Bom, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Menditto, E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Passalacqua, G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stellato, C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Triggiani, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ventura, M. T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Vezzani, G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Annesi-Maesano, I.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bourret, R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bosse, I.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Caimmi, D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cartier, C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Demoly, P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Just, J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Portejoie, F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Siroux, V.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Viart, F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bergmann, K. C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Keil, T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Klimek, L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Moesges, R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pfaar, O.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Shamai, S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Zuberbier, T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mullol, J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Valero, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Spranger, O.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Tomazic, P. V.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kowalski, M. L.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kuna, P.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kupczyk, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Raciborski, F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Samolinski, B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Toppila-Salmi, S. K.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Valovirta, E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Cruz, A. A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sarquis-Serpa, F.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
da Silva, J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Stelmach, R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Larenas-Linnemann, D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rodriguez Gonzalez, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Burguete Cabanas, M. T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kvedariene, V.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Valiulis, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chavannes, N. H.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Fokkens, W. J.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ryan, D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sheikh, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bachert, C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hellings, P. W.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
VandenPlas, O.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ballardini, N.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Kull, I.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Melen, E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Westman, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Wickman, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bindslev-Jensen, C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Eller, E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bosnic-Anticevich, S.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
O'Hehir, R. E.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Agache, I.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Bieber, T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Casale, T.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gemicioglu, B.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ivancevich, J. C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
De Vries, G.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Sorensen, M.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Yorgancioglu, A.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Laune, D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-177049
DOI: 10.1111/all.13448
Journal or Publication Title: Allergy
Volume: 73
Number: 8
Page Range: S. 1622 - 1632
Date: 2018
Publisher: WILEY
Place of Publication: HOBOKEN
ISSN: 1398-9995
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
WORLD-HEALTH-ORGANIZATION; VISUAL ANALOG SCALE; QUALITY-OF-LIFE; ASTHMA; MEDALL; IMPACT; MECHANISMS; SYMPTOMS; CHILDREN; GA(2)LENMultiple languages
Allergy; ImmunologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/17704

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