Universität zu Köln

Schmidt, Matthias, Goerges, Rainer, Drzezga, Alexander and Dietlein, Markus (2018). A Matter of Controversy: Is Radioiodine Therapy Favorable in Differentiated Thyroid Carcinoma? J. Nucl. Med., 59 (8). S. 1195 - 1202. RESTON: SOC NUCLEAR MEDICINE INC. ISSN 1535-5667

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Abstract

Radioiodine therapy is a matter of controversy because different opinions exist about its use for differentiated thyroid carcinoma. The following article sheds light on the different opinions and explains why we advocate the use of radioiodine therapy in more than only high-risk patients. In comparison to other malignancies, differentiated thyroid carcinoma has a different tumor biology due to its usually slow growth pattern. Radioiodine therapy was first used about 75 y ago and provided cure at a time when prospective randomized controlled trials had yet to be developed. Large patient cohorts and usually at least a decade of clinical follow-up are needed to demonstrate a benefit from radioiodine therapy. Thus, especially in low-risk patients, many factors define an individual treatment decision, including tumor stage, extent of surgery, tumor biology, clinical and imaging data, life expectancy, and patient preferences.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schmidt, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED Goerges, Rainer UNSPECIFIED UNSPECIFIED UNSPECIFIED Drzezga, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Dietlein, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-178630
DOI:	10.2967/jnumed.117.191338
Journal or Publication Title:	J. Nucl. Med.
Volume:	59
Number:	8
Page Range:	S. 1195 - 1202
Date:	2018
Publisher:	SOC NUCLEAR MEDICINE INC
Place of Publication:	RESTON
ISSN:	1535-5667
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ASSOCIATION MANAGEMENT GUIDELINES; RADIOACTIVE IODINE THERAPY; 2ND PRIMARY MALIGNANCIES; LYMPH-NODE DISSECTION; REMNANT ABLATION; ADULT PATIENTS; POSTOPERATIVE ABLATION; SERUM THYROGLOBULIN; NUCLEAR FEATURES; CANCER PATIENTS Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/17863