Lehmann, Helmar C., Compston, Alastair and Hartung, Hans-Peter (2018). 150th anniversary of clinical description of multiple sclerosis Leopold Ordenstein's legacy. Neurology, 90 (22). S. 1011 - 1017. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1526-632X

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Abstract

The clinical features of multiple sclerosis were first defined in detail and with pathologic confirmation in a medical thesis published at the Salpetriere, Paris, in 1868. The author, Leopold Ordenstein (1835-1902), a German physician, analyzed cases collected by his mentor, Jean-Martin Charcot (1825-1893). The 2 clinician-scientists described the characteristic symptoms, predisposing age, and pathologic features of the disease, and emphasized the clear delineation from other chronic progressive disorders, especially paralysis agitans. The latter was referred to as Parkinson disease by William Sanders in 1865 and adopted by Desire-Magloire Bourneville on behalf of Charcot in 1875. This essay commemorates the 150th anniversary of the publication of the pioneering work of Leopold Ordenstein and Jean-Martin Charcot.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Lehmann, Helmar C.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Compston, AlastairUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hartung, Hans-PeterUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-185918
DOI: 10.1212/WNL.0000000000005613
Journal or Publication Title: Neurology
Volume: 90
Number: 22
Page Range: S. 1011 - 1017
Date: 2018
Publisher: LIPPINCOTT WILLIAMS & WILKINS
Place of Publication: PHILADELPHIA
ISSN: 1526-632X
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
Clinical NeurologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/18591

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