Universität zu Köln

Schultze-Lutter, Frauke, Michel, Chantal ORCID: 0000-0003-1165-6681, Ruhrmann, Stephan ORCID: 0000-0002-6022-2364 and Schimmelmann, Benno G. (2018). Prevalence and clinical relevance of interview-assessed psychosis-risk symptoms in the young adult community. Psychol. Med., 48 (7). S. 1167 - 1179. NEW YORK: CAMBRIDGE UNIV PRESS. ISSN 1469-8978

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Abstract

Background. An efficient indicated prevention of psychotic disorders requires valid risk criteria that work in both clinical and community samples. Yet, ultra-high risk and basic symptom criteria were recently recommended for use in clinical samples only. Their use in the community was discouraged for lack of knowledge about their prevalence, clinical relevance and risk factors in non-clinical, community settings when validly assessed with the same instruments used in the clinic. Methods. Using semi-structured telephone interviews with established psychosis-risk instruments, we studied the prevalence of psychosis-risk symptoms and criteria, their clinical relevance (using presence of a non-psychotic mental disorder or of functional deficits as proxy measures) and their risk factors in a random, representative young adult community sample (N=2683; age 16-40 years; response rate: 63.4%). Results. The point-prevalence of psychosis-risk symptoms was 13.8%. As these mostly occurred too infrequent to meet frequency requirements of psychosis-risk criteria, only 2.4% of participants met psychosis-risk criteria. A stepwise relationship underlay the association of ultra-high risk and basic symptoms with proxy measures of clinical relevance, this being most significant when both occurred together. In line with models of their formation, basic symptoms were selectively associated with age, ultra-high risk symptoms with traumatic events and lifetime substance misuse. Conclusions. Psychosis-risk criteria were uncommon, indicating little risk of falsely labelling individuals from the community at-risk for psychosis. Besides, both psychosis-risk symptoms and criteria seem to possess sufficient clinical relevance to warrant their broader attention in clinical practice, especially if ultra-high risk and basic symptoms occur together.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schultze-Lutter, Frauke UNSPECIFIED UNSPECIFIED UNSPECIFIED Michel, Chantal UNSPECIFIED orcid.org/0000-0003-1165-6681 UNSPECIFIED Ruhrmann, Stephan UNSPECIFIED orcid.org/0000-0002-6022-2364 UNSPECIFIED Schimmelmann, Benno G. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-188858
DOI:	10.1017/S0033291717002586
Journal or Publication Title:	Psychol. Med.
Volume:	48
Number:	7
Page Range:	S. 1167 - 1179
Date:	2018
Publisher:	CAMBRIDGE UNIV PRESS
Place of Publication:	NEW YORK
ISSN:	1469-8978
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language TO-FACE INTERVIEWS; GENERAL-POPULATION; MENTAL-HEALTH; HELP-SEEKING; DISORDERS; EXPERIENCES; SCHIZOPHRENIA; METAANALYSIS; ADOLESCENTS; CRITERIA Multiple languages Psychology, Clinical; Psychiatry; Psychology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/18885