Universität zu Köln

Zugor, Vahudin, Von Brandenstein, Melanie, Akbarov, Ilgar, Porres, Daniel, Kuhn, Reinhard and Labanaris, Apostolos P. (2018). Preoperative Stating of Pelvic Lymph Nodes in Prostate Cancer Patients via Endorectal Magnetic Resonance Imaging. Anticancer Res., 38 (3). S. 1763 - 1766. ATHENS: INT INST ANTICANCER RESEARCH. ISSN 1791-7530

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Abstract

Background/Aim: The aim of this study was to evaluate the diagnostic sensitivity, specificity and accuracy of endorectal magnetic resonance imaging (e-MRI), as a preoperative staging modality in the diagnosis of lymph node metastasis (LNM) in patients with prostate cancer (PCa). Patients and Methods: Retrospectively, we analyzed data from N=168 patients who underwent radical prostatectomy (RP) between 2004 and 2013 at two tertiary medical centres. Prior to RP all patients underwent an e-MRI. Inclusion criteria were: PSA levels >20 ng/ml or Gleason score >7. Examinations were performed on a closed 1.0-T system combined with an endorectal body phased-array coil, imaging results were correlated with histopathology. Results: 10.7% (N=18 patients) had histologically-proven LNM. e-MRI was true-positive in N=6 (33.3%) and false-negative N=12 patients (66.6%). N=150 (89.3%) patients without LNM e-MRI were true-negative in 96% and false-positive in 4%. Sensitivity was 96%, specificity was 33%, accuracy was 64.5%. Conclusion: eMRI can be considered a useful preoperative staging modality in diagnosis of LNM.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Zugor, Vahudin UNSPECIFIED UNSPECIFIED UNSPECIFIED Von Brandenstein, Melanie UNSPECIFIED UNSPECIFIED UNSPECIFIED Akbarov, Ilgar UNSPECIFIED UNSPECIFIED UNSPECIFIED Porres, Daniel UNSPECIFIED UNSPECIFIED UNSPECIFIED Kuhn, Reinhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Labanaris, Apostolos P. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-194158
DOI:	10.21873/anticanres.12413
Journal or Publication Title:	Anticancer Res.
Volume:	38
Number:	3
Page Range:	S. 1763 - 1766
Date:	2018
Publisher:	INT INST ANTICANCER RESEARCH
Place of Publication:	ATHENS
ISSN:	1791-7530
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RADICAL RETROPUBIC PROSTATECTOMY; MULTIPARAMETRIC-MRI; METASTASES; PET/CT; LYMPHADENECTOMY; FAILURE; BIOPSY; RISK; CT Multiple languages Oncology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/19415