Hickethier, Tilman, Byrtus, Jonathan, Hauger, Myriam, Iuga, Andra-Iza, Pahn, Gregor, Maintz, David, Haneder, Stefan and Doerner, Jonas (2018). Utilization of virtual mono-energetic images (MonoE) derived from a dual-layer spectral detector CT (SDCT) for the assessment of abdominal arteries in venous contrast phase scans. Eur. J. Radiol., 99. S. 28 - 34. CLARE: ELSEVIER IRELAND LTD. ISSN 1872-7727

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Abstract

Objectives: To investigate the utilization of virtual mono-energetic images (MonoE) at low kiloelectron volt (keV) levels derived from a dual-layer spectral detector CT (SDCT) for the assessment of abdominal arteries in venous contrast phase scans using arterial phase imaging as an internal reference standard. Materials and methods: A total of 50 patients who received arterial and venous phase imaging of the abdomen on a SDCT system were included in this study. Absolute attenuation, noise, signal-and contrast to noise ratios (SNR; CNR) as well as arterial diameters in defined landmarks were assessed. In arterial phase, conventional reconstructions (CRART) as well as MonoE(ART) at 40 keV and in venous phase, conventional reconstructions (CRVEN) as well as MonoE(VEN) at 70 and 40 keV were investigated and intra-individual comparisons were performed. If an artery stenosis (10 patients) was present, the degree of stenosis was assessed according to the system of the North American Symptomatic Carotid Endarterectomy Trial (NASCET). Results: MonoE 40 keV yielded significantly higher attenuation values (in arterial as well as in venous phase) compared to CRART (p < 0.001) while noise levels were substantially low. This resulted in markedly superior SNR and CNR in large vessel compared to CRART. Luminal diameters were significantly smaller in MonoE 40 keV in both contrast phases compared to CRART (p < 0.001), whereas no significant differences were found between both MonoE reconstructions (p >= 0.92). The degree of vessel stenosis was significantly higher in MonoE 40 keV of both contrast phases compared to CRART (p >= 0.02). Conclusion: MonoE at low keV of venous contrast phase scans derived from a novel SDCT are suitable for the assessment of arteries in the abdomen and subsequent stenosis assessment. However, MonoE at 40 keV constantly showed significant smaller luminal diameters than the corresponding conventional reconstructions (including the reference standard). This is possibly due to an improved differentiation of the vessel lumen from the wall and raises the question, which imaging technique should be used as an appropriate reference standard for vascular SDCT imaging studies.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Hickethier, TilmanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Byrtus, JonathanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hauger, MyriamUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Iuga, Andra-IzaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Pahn, GregorUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Maintz, DavidUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Haneder, StefanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Doerner, JonasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-198110
DOI: 10.1016/j.ejrad.2017.12.007
Journal or Publication Title: Eur. J. Radiol.
Volume: 99
Page Range: S. 28 - 34
Date: 2018
Publisher: ELSEVIER IRELAND LTD
Place of Publication: CLARE
ISSN: 1872-7727
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
KILOELECTRON VOLT SETTINGS; ENERGY CT; ANGIOGRAPHY; OPTIMIZATION; ALGORITHM; QUALITYMultiple languages
Radiology, Nuclear Medicine & Medical ImagingMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/19811

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