Universität zu Köln

Gutknecht, Mandy, Schaarschmidt, Marthe-Lisa, Danner, Marion, Blome, Christine and Augustin, Matthias (2018). Measuring the importance of health domains in psoriasis - discrete choice experiment versus rating scales. Patient Prefer. Adherence, 12. S. 363 - 374. ALBANY: DOVE MEDICAL PRESS LTD. ISSN 1177-889X

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Abstract

Background: Psoriasis affects different aspects of health-related quality of life (eg, physical, psychological, and social impairments); these health domains can be of different importance for patients. The importance of domains can be measured with the Patient Benefit Index (PBI). This questionnaire weights the achievement of treatment goals by Likert scales (0, not important at all to 4, very important) using the Patient Needs Questionnaire (PNQ). Treatment goals assessed with the PBI have been assigned to five health domains; the importance of each domain can be calculated as the average importance of the respective treatment goals. In this study, the PBI approach of deriving importance weights is contrasted to a discrete choice experiment (DCE), in order to determine the importance of health domains in psoriasis, and to find if the resulting weights will differ when derived from these two methods. Methods: Adult patients with psoriasis completed both questionnaires (PNQ, DCE). The PBI domains were used as attributes in the DCE with the levels did not help at all, helped moderately, and helped a lot. Results: Using DCE, improving physical functioning was the most important health domain, followed by improving psychological well-being. Using PNQ, these domains were ranked in position two and three following strengthening confidence in the therapy and in a possible healing. The latter was least important using DCE. The only agreement of ranking was shown in reducing impairments due to therapy (position four). Improving social functioning was ranked in position three (DCE) and five (PNQ). Conclusion: Health domains have different importance to patients with psoriasis. Using PNQ or DCE to determine the importance of domains results in markedly different rankings; both approaches can thus not be considered equivalent. However, in this study, importance was assessed at the domain level in DCE and at the single item level in PNQ, which may have added to the differences.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Gutknecht, Mandy UNSPECIFIED UNSPECIFIED UNSPECIFIED Schaarschmidt, Marthe-Lisa UNSPECIFIED UNSPECIFIED UNSPECIFIED Danner, Marion UNSPECIFIED UNSPECIFIED UNSPECIFIED Blome, Christine UNSPECIFIED UNSPECIFIED UNSPECIFIED Augustin, Matthias UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-203309
DOI:	10.2147/PPA.S152509
Journal or Publication Title:	Patient Prefer. Adherence
Volume:	12
Page Range:	S. 363 - 374
Date:	2018
Publisher:	DOVE MEDICAL PRESS LTD
Place of Publication:	ALBANY
ISSN:	1177-889X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CONJOINT-ANALYSIS; IMPORTANCE WEIGHTS; PREFERENCES; BURDEN; CARE Multiple languages Medicine, General & Internal Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/20330