Universität zu Köln

Kalbe, Elke, Aarsland, Dag ORCID: 0000-0001-6314-216X and Folkerts, Ann-Kristin (2018). Cognitive Interventions in Parkinson's Disease: Where We Want to Go within 20 Years. J. Parkinsons Dis., 8. S. S107 - 7. AMSTERDAM: IOS PRESS. ISSN 1877-718X

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Abstract

Today, meta-analyses demonstrate that cognitive training is safe and effective to enhance vulnerable cognitive functions in patients with Parkinson's disease (PD), so that cognitive interventions can be regarded as a promising approach to treat or even prevent cognitive dysfunction in PD. However, many research gaps exist. Thus, this article aims to identify relevant research topics with regard to cognitive interventions in PD patients for the next 20 years. The most important to do ' s include the development of (non-digital and digital, maybe also artificial intelligence based) standardized cognitive interventions for PD patients in different cognitive stages and the conduct of large randomized controlled trials (RCTs) in these groups, also considering different patient profiles (e.g., motor subtypes) and the living setting (inpatient versus outpatient). The impact of cognitive and combined interventions in individuals with prodromal PD is of high relevance. Studies should elucidate underlying mechanisms of cognitive and neural plasticity induced by cognitive interventions and propose prediction models on which patients profit from which intervention. Health-economic analyses are also urgently needed. More generally, increasing the awareness of the concept of cognitive reserve and possibilities for the prevention of cognitive dysfunction is an important goal.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kalbe, Elke UNSPECIFIED UNSPECIFIED UNSPECIFIED Aarsland, Dag UNSPECIFIED orcid.org/0000-0001-6314-216X UNSPECIFIED Folkerts, Ann-Kristin UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-205025
DOI:	10.3233/JPD-181473
Journal or Publication Title:	J. Parkinsons Dis.
Volume:	8
Page Range:	S. S107 - 7
Date:	2018
Publisher:	IOS PRESS
Place of Publication:	AMSTERDAM
ISSN:	1877-718X
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language Neurosciences Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/20502