Universität zu Köln

Lueken, Ulrike, Evens, Ricarda, Balzer-Geldsetzer, Monika, Baudrexel, Simon, Dodel, Richard, Graeber-Sultan, Susanne, Hilker-Roggendorf, Ruediger, Kalbe, Elke, Kaut, Oliver, Mollenhauer, Brit, Reetz, Kathrin, Schaeffer, Eva, Schmidt, Nele, Schulz, Joerg B., Spottke, Annika, Witt, Karsten, Linse, Katharina, Storch, Alexander and Riedel, Oliver (2017). Psychometric properties of the apathy evaluation scale in patients with Parkinson's disease. Int. J. Methods Psychiatr. Res., 26 (4). HOBOKEN: WILEY. ISSN 1557-0657

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Abstract

Parkinson's disease (PD) frequently entails non-motor symptoms, worsening the course of the disease. Apathy is one of the core neuropsychiatric symptoms that has been investigated in recent years; research is however hampered by the limited availability of well-evaluated apathy scales for these patients. We evaluated the psychometric properties of the Apathy Evaluation Scale (AES) in a sample of PD patients. Psychometric properties, convergent and discriminant validity and sensitivity/specificity were evaluated in patients with (n=582) or without dementia/depression (n=339). Internal consistency was high in the entire sample as well as in patients without dementia/depression. Correlations were moderate for convergent validity (UPDRS I item 4: motivation). While apathy could be differentiated from cognitive decline, it was related to depression (Geriatric Depression Scale, GDS-15). The overall classification accuracy based on the UPDRS I item 4 was comparable for AES and GDS scores. The AES exhibits good psychometric properties in PD patients with and without dementia and/or depression. Commonly used screenings on the presence of apathy had low detection rates compared to the AES and reflected both apathetic and depressive symptoms. Psychometric evaluation of available instruments will support further research on the clinical relevance of apathy for disease progression and treatment approaches in PD patients.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Lueken, Ulrike UNSPECIFIED UNSPECIFIED UNSPECIFIED Evens, Ricarda UNSPECIFIED UNSPECIFIED UNSPECIFIED Balzer-Geldsetzer, Monika UNSPECIFIED UNSPECIFIED UNSPECIFIED Baudrexel, Simon UNSPECIFIED UNSPECIFIED UNSPECIFIED Dodel, Richard UNSPECIFIED UNSPECIFIED UNSPECIFIED Graeber-Sultan, Susanne UNSPECIFIED UNSPECIFIED UNSPECIFIED Hilker-Roggendorf, Ruediger UNSPECIFIED UNSPECIFIED UNSPECIFIED Kalbe, Elke UNSPECIFIED UNSPECIFIED UNSPECIFIED Kaut, Oliver UNSPECIFIED UNSPECIFIED UNSPECIFIED Mollenhauer, Brit UNSPECIFIED UNSPECIFIED UNSPECIFIED Reetz, Kathrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Schaeffer, Eva UNSPECIFIED UNSPECIFIED UNSPECIFIED Schmidt, Nele UNSPECIFIED UNSPECIFIED UNSPECIFIED Schulz, Joerg B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Spottke, Annika UNSPECIFIED UNSPECIFIED UNSPECIFIED Witt, Karsten UNSPECIFIED UNSPECIFIED UNSPECIFIED Linse, Katharina UNSPECIFIED UNSPECIFIED UNSPECIFIED Storch, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED Riedel, Oliver UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-210164
DOI:	10.1002/mpr.1564
Journal or Publication Title:	Int. J. Methods Psychiatr. Res.
Volume:	26
Number:	4
Date:	2017
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1557-0657
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language RATING-SCALE; NEUROPSYCHIATRIC SYMPTOMS; COGNITIVE IMPAIRMENT; DIAGNOSTIC-CRITERIA; CLINICAL-PRACTICE; DEMENTIA; DEPRESSION; RECOMMENDATIONS; PREVALENCE; VALIDATION Multiple languages Psychiatry Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/21016