Universität zu Köln

Tsubouchi, Asako ORCID: 0000-0002-6284-8221, Yano, Tomoko, Yokoyama, Takeshi K., Murtin, Chloe, Otsuna, Hideo ORCID: 0000-0002-2107-8881 and Ito, Kei ORCID: 0000-0002-7274-5533 (2017). Topological and modality-specific representation of somatosensory information in the fly brain. Science, 358 (6363). S. 615 - 623. WASHINGTON: AMER ASSOC ADVANCEMENT SCIENCE. ISSN 1095-9203

Full text not available from this repository.

Abstract

Insects and mammals share similarities of neural organization underlying the perception of odors, taste, vision, sound, and gravity. We observed that insect somatosensation also corresponds to that of mammals. In Drosophila, the projections of all the somatosensory neuron types to the insect's equivalent of the spinal cord segregated into modality-specific layers comparable to those in mammals. Some sensory neurons innervate the ventral brain directly to form modality-specific and topological somatosensory maps. Ascending interneurons with dendrites in matching layers of the nerve cord send axons that converge to respective brain regions. Pathways arising from leg somatosensory neurons encode distinct qualities of leg movement information and play different roles in ground detection. Establishment of the ground pattern and genetic tools for neuronal manipulation should provide the basis for elucidating the mechanisms underlying somatosensation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Tsubouchi, Asako UNSPECIFIED orcid.org/0000-0002-6284-8221 UNSPECIFIED Yano, Tomoko UNSPECIFIED UNSPECIFIED UNSPECIFIED Yokoyama, Takeshi K. UNSPECIFIED UNSPECIFIED UNSPECIFIED Murtin, Chloe UNSPECIFIED UNSPECIFIED UNSPECIFIED Otsuna, Hideo UNSPECIFIED orcid.org/0000-0002-2107-8881 UNSPECIFIED Ito, Kei UNSPECIFIED orcid.org/0000-0002-7274-5533 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-211550
DOI:	10.1126/science.aan4428
Journal or Publication Title:	Science
Volume:	358
Number:	6363
Page Range:	S. 615 - 623
Date:	2017
Publisher:	AMER ASSOC ADVANCEMENT SCIENCE
Place of Publication:	WASHINGTON
ISSN:	1095-9203
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language SENSORY NEURONS; DROSOPHILA-MELANOGASTER; MOTOR CONTROL; CAMPANIFORM SENSILLA; MOLECULAR-MECHANISMS; AFFERENT-PROJECTIONS; CHORDOTONAL ORGANS; COMMON PRINCIPLES; NERVOUS-SYSTEM; CELLULAR BASIS Multiple languages Multidisciplinary Sciences Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/21155