Kovacs, Gabor, Herve, Philippe, Barbera, Joan Albert, Chaouat, Ari, Chemla, Denis, Condliffe, Robin ORCID: 0000-0002-3492-4143, Garcia, Gilles, Grunig, Ekkehard, Howard, Luke, Humbert, Marc ORCID: 0000-0003-0703-2892, Lau, Edmund, Laveneziana, Pierantonio, Lewis, Gregory D., Naeije, Robert, Peacock, Andrew, Rosenkranz, Stephan, Saggar, Rajeev, Ulrich, Silvia ORCID: 0000-0002-5250-5022, Vizza, Dario, Noordegraaf, Anton Vonk and Olschewski, Horst ORCID: 0000-0002-2834-7466 (2017). An official European Respiratory Society statement: pulmonary haemodynamics during exercise. Eur. Resp. J., 50 (5). SHEFFIELD: EUROPEAN RESPIRATORY SOC JOURNALS LTD. ISSN 1399-3003

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Abstract

There is growing recognition of the clinical importance of pulmonary haemodynamics during exercise, but several questions remain to be elucidated. The goal of this statement is to assess the scientific evidence in this field in order to provide a basis for future recommendations. Right heart catheterisation is the gold standard method to assess pulmonary haemodynamics at rest and during exercise. Exercise echocardiography and cardiopulmonary exercise testing represent non-invasive tools with evolving clinical applications. The term exercise pulmonary hypertension may be the most adequate to describe an abnormal pulmonary haemodynamic response characterised by an excessive pulmonary arterial pressure (PAP) increase in relation to flow during exercise. Exercise pulmonary hypertension may be defined as the presence of resting mean PAP < 25 mmHg and mean PAP > 30 mmHg during exercise with total pulmonary resistance > 3 Wood units. Exercise pulmonary hypertension represents the haemodynamic appearance of early pulmonary vascular disease, left heart disease, lung disease or a combination of these conditions. Exercise pulmonary hypertension is associated with the presence of a modest elevation of resting mean PAP and requires clinical follow-up, particularly if risk factors for pulmonary hypertension are present. There is a lack of robust clinical evidence on targeted medical therapy for exercise pulmonary hypertension.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Kovacs, GaborUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Herve, PhilippeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Barbera, Joan AlbertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chaouat, AriUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Chemla, DenisUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Condliffe, RobinUNSPECIFIEDorcid.org/0000-0002-3492-4143UNSPECIFIED
Garcia, GillesUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Grunig, EkkehardUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Howard, LukeUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Humbert, MarcUNSPECIFIEDorcid.org/0000-0003-0703-2892UNSPECIFIED
Lau, EdmundUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Laveneziana, PierantonioUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Lewis, Gregory D.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Naeije, RobertUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Peacock, AndrewUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rosenkranz, StephanUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Saggar, RajeevUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Ulrich, SilviaUNSPECIFIEDorcid.org/0000-0002-5250-5022UNSPECIFIED
Vizza, DarioUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Noordegraaf, Anton VonkUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Olschewski, HorstUNSPECIFIEDorcid.org/0000-0002-2834-7466UNSPECIFIED
URN: urn:nbn:de:hbz:38-213392
DOI: 10.1183/13993003.00578-2017
Journal or Publication Title: Eur. Resp. J.
Volume: 50
Number: 5
Date: 2017
Publisher: EUROPEAN RESPIRATORY SOC JOURNALS LTD
Place of Publication: SHEFFIELD
ISSN: 1399-3003
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
STRESS DOPPLER-ECHOCARDIOGRAPHY; RIGHT HEART CATHETERIZATION; PRESERVED EJECTION FRACTION; CONNECTIVE-TISSUE DISEASE; PRESSURE-FLOW RELATIONSHIPS; ARTERIAL-HYPERTENSION; SYSTEMIC-SCLEROSIS; WEDGE PRESSURE; STROKE VOLUME; GAS-EXCHANGEMultiple languages
Respiratory SystemMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/21339

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