Universität zu Köln

Danner, Marion, Vennedey, Vera, Hiligsmann, Mickaeel, Fauser, Sascha, Gross, Christian and Stock, Stephanie (2017). Comparing Analytic Hierarchy Process and Discrete-Choice Experiment to Elicit Patient Preferences for Treatment Characteristics in Age-Related Macular Degeneration. Value Health, 20 (8). S. 1166 - 1174. NEW YORK: ELSEVIER SCIENCE INC. ISSN 1524-4733

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Abstract

Background: In this study, we conducted an analytic hierarchy process (AHP) and a discrete choice experiment (DCE) to elicit the preferences of patients with age-related macular degeneration using identical attributes and levels. Objectives: To compare preference based weights for age-related macular degeneration treatment attributes and levels generated by two elicitation methods. The properties of both methods were assessed, including ease of instrument use. Methods: A DCE and an AHP experiment were designed on the basis of five attributes. Preference-based weights were generated using the matrix multiplication method for attributes and levels in AHP and a mixed multinomial logit model for levels in the DCE. Attribute importance was further compared using coefficient (DCE) and weight (AHP) level ranges. The questionnaire difficulty was rated on a qualitative scale. Patients were asked to think aloud while providing their judgments. Results: AHP and DCE generated similar results regarding levels, stressing a preference for visual improvement, frequent monitoring, on-demand and less frequent injection schemes, approved drugs, and mild side effects. Attribute weights derived on the basis of level ranges led to a ranking that was opposite to the AHP directly calculated attribute weights. For example, visual function ranked first in the AHP and last on the basis of level ranges. Conclusions: The results across the methods were similar, with one exception: the directly measured AHP attribute weights were different from the level-based interpretation of attribute importance in both DCE and AHP. The dependence/independence of attribute importance on level ranges in DCE and AHP, respectively, should be taken into account when choosing a method to support decision making.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Danner, Marion UNSPECIFIED UNSPECIFIED UNSPECIFIED Vennedey, Vera UNSPECIFIED UNSPECIFIED UNSPECIFIED Hiligsmann, Mickaeel UNSPECIFIED UNSPECIFIED UNSPECIFIED Fauser, Sascha UNSPECIFIED UNSPECIFIED UNSPECIFIED Gross, Christian UNSPECIFIED UNSPECIFIED UNSPECIFIED Stock, Stephanie UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-218604
DOI:	10.1016/j.jval.2017.04.022
Journal or Publication Title:	Value Health
Volume:	20
Number:	8
Page Range:	S. 1166 - 1174
Date:	2017
Publisher:	ELSEVIER SCIENCE INC
Place of Publication:	NEW YORK
ISSN:	1524-4733
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MULTICRITERIA DECISION-ANALYSIS; ELDERLY OPHTHALMOLOGIC PATIENTS; OF-THE-LITERATURE; CONJOINT-ANALYSIS; HEALTH-CARE; TASK-FORCE; TUTORIAL; INSIGHTS Multiple languages Economics; Health Care Sciences & Services; Health Policy & Services Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/21860