Universität zu Köln

Kononenko, Natalia L. (2017). Lysosomes convene to keep the synapse clean. J. Cell Biol., 216 (8). S. 2251 - 2254. NEW YORK: ROCKEFELLER UNIV PRESS. ISSN 1540-8140

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Abstract

In neurons, lysosomes regulate alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor levels at the plasma membrane, although their presence at distal dendrites is controversial. In this issue, Goo et al. (2017. J. Cell Biol. https://doi.org/10.1083/jcb.201704068) show for the first time that neuronal activity positions lysosomes at the dendritic spines to facilitate synaptic remodeling through local protein degradation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Kononenko, Natalia L. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-223127
DOI:	10.1083/jcb.201707070
Journal or Publication Title:	J. Cell Biol.
Volume:	216
Number:	8
Page Range:	S. 2251 - 2254
Date:	2017
Publisher:	ROCKEFELLER UNIV PRESS
Place of Publication:	NEW YORK
ISSN:	1540-8140
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language LONG-TERM DEPRESSION; TRAFFICKING; DEGRADATION Multiple languages Cell Biology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/22312