van Koningsbruggen-Rietschel, S. and Rietschel, E. (2017). Cystic fibrosis. Disease on the way to personalized therapy. Mon.schr. Kinderheilkd., 165 (8). S. 681 - 688. NEW YORK: SPRINGER. ISSN 1433-0474
Full text not available from this repository.Abstract
By the introduction of newborn screening it has become possible in most patients to implement symptomatic therapy for cystic fibrosis in the first weeks of life. The life expectancy and the quality of life of patients and their families will be improved by this implementation. Many mutation-specific therapies as well as mutation-agnostic treatments are in preclinical and clinical development and two have already been approved. Because of the difficulties in evaluating the individual effectiveness of these therapies by using clinical parameters alone, measurement of improved chloride channel function in vivo and in vitro is becoming more important.
Item Type: | Journal Article | ||||||||||||
Creators: |
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URN: | urn:nbn:de:hbz:38-223261 | ||||||||||||
DOI: | 10.1007/s00112-017-0322-0 | ||||||||||||
Journal or Publication Title: | Mon.schr. Kinderheilkd. | ||||||||||||
Volume: | 165 | ||||||||||||
Number: | 8 | ||||||||||||
Page Range: | S. 681 - 688 | ||||||||||||
Date: | 2017 | ||||||||||||
Publisher: | SPRINGER | ||||||||||||
Place of Publication: | NEW YORK | ||||||||||||
ISSN: | 1433-0474 | ||||||||||||
Language: | German | ||||||||||||
Faculty: | Unspecified | ||||||||||||
Divisions: | Unspecified | ||||||||||||
Subjects: | no entry | ||||||||||||
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Refereed: | Yes | ||||||||||||
URI: | http://kups.ub.uni-koeln.de/id/eprint/22326 |
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