Bagshaw, Emma, Kuessner, Daniel, Posthumus, Jan, Escrig, Cesar, Blackney, Michael, Heimann, Sebastian Marcel and Cornely, Oliver Andreas (2017). The cost of treating mucormycosis with isavuconazole compared with standard therapy in the UK. Future Microbiol., 12 (6). S. 514 - 525. LONDON: FUTURE MEDICINE LTD. ISSN 1746-0921
Full text not available from this repository.Abstract
Aim: Mucormycosis is a fungal infection associated with high mortality. Until recently, the only licensed treatments were amphotericin B (AMB) formulations. Isavuconazole (ISAV) is a new mucormycosis treatment. A UK-based economic model explored treatment costs with ISAV versus liposomal AMB followed by posaconazole. Materials & methods: As a matched case-control analysis showed similar efficacy for ISAV and AMB, a cost-minimization approach was taken. Direct costs - drug acquisition, monitoring and administration, and hospitalization costs - were estimated from the National Health Service perspective. Results: Per-patient costs for ISAV and liposomal AMB + posaconazole were UK(sic)26,810 and UK(sic)41,855, respectively, with savings primarily driven by drug acquisition and hospitalization costs. Conclusion: ISAV may reduce costs compared with standard mucormycosis therapy.
Item Type: | Journal Article | ||||||||||||||||||||||||||||||||
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URN: | urn:nbn:de:hbz:38-231648 | ||||||||||||||||||||||||||||||||
DOI: | 10.2217/fmb-2016-0231 | ||||||||||||||||||||||||||||||||
Journal or Publication Title: | Future Microbiol. | ||||||||||||||||||||||||||||||||
Volume: | 12 | ||||||||||||||||||||||||||||||||
Number: | 6 | ||||||||||||||||||||||||||||||||
Page Range: | S. 514 - 525 | ||||||||||||||||||||||||||||||||
Date: | 2017 | ||||||||||||||||||||||||||||||||
Publisher: | FUTURE MEDICINE LTD | ||||||||||||||||||||||||||||||||
Place of Publication: | LONDON | ||||||||||||||||||||||||||||||||
ISSN: | 1746-0921 | ||||||||||||||||||||||||||||||||
Language: | English | ||||||||||||||||||||||||||||||||
Faculty: | Unspecified | ||||||||||||||||||||||||||||||||
Divisions: | Unspecified | ||||||||||||||||||||||||||||||||
Subjects: | no entry | ||||||||||||||||||||||||||||||||
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Refereed: | Yes | ||||||||||||||||||||||||||||||||
URI: | http://kups.ub.uni-koeln.de/id/eprint/23164 |
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