Universität zu Köln

Doehner, Wolfram, Blankenberg, Stefan, Erdmann, Erland, Ertl, Georg, Hasenfuss, Gerd, Landmesser, Ulf, Pieske, Burkert, Schieffer, Bernhard, Schunkert, Heribert, von Haehling, Stephan, Zeiher, Andreas and Anker, Stefan D. (2017). Iron Deficiency in Chronic Heart Failure: Diagnostic Algorithm and Present-Day Therapeutic Options. Dtsch. Med. Wochenschr., 142 (10). S. 752 - 758. STUTTGART: GEORG THIEME VERLAG KG. ISSN 1439-4413

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Abstract

Iron deficiency (ID) occurs in up to 50% of patients with heart failure (HF). Even without presence of anaemia ID contributes to more severe symptoms, increased hospitalization and mortality. A number of randomized controlled trials demonstrated the clinical benefit of replenishment of iron stores with improvement of symptoms and fewer hospitalizations. Assessment of iron status should therefore become routine assessment in newly diagnosed and in symptomatic patients with HF. ID can be identified with simple and straightforward diagnostic steps. Assessment of Ferritin (indicating iron stores) and transferrin saturation (TSAT, indication capability to mobilise internal iron stores) are sufficient to detect ID. In this review a plain diagnostic algorithm for ID is suggested. Confounding factors for diagnosis and adequate treatment of ID in HF are discussed. A regular workup for iron deficiency parameters may benefit patients with heart failure by providing symptomatic improvements and fewer hospitalizations.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Doehner, Wolfram UNSPECIFIED UNSPECIFIED UNSPECIFIED Blankenberg, Stefan UNSPECIFIED UNSPECIFIED UNSPECIFIED Erdmann, Erland UNSPECIFIED UNSPECIFIED UNSPECIFIED Ertl, Georg UNSPECIFIED UNSPECIFIED UNSPECIFIED Hasenfuss, Gerd UNSPECIFIED UNSPECIFIED UNSPECIFIED Landmesser, Ulf UNSPECIFIED UNSPECIFIED UNSPECIFIED Pieske, Burkert UNSPECIFIED UNSPECIFIED UNSPECIFIED Schieffer, Bernhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Schunkert, Heribert UNSPECIFIED UNSPECIFIED UNSPECIFIED von Haehling, Stephan UNSPECIFIED UNSPECIFIED UNSPECIFIED Zeiher, Andreas UNSPECIFIED UNSPECIFIED UNSPECIFIED Anker, Stefan D. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-231682
DOI:	10.1055/s-0043-100900
Journal or Publication Title:	Dtsch. Med. Wochenschr.
Volume:	142
Number:	10
Page Range:	S. 752 - 758
Date:	2017
Publisher:	GEORG THIEME VERLAG KG
Place of Publication:	STUTTGART
ISSN:	1439-4413
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language FERRIC CARBOXYMALTOSE; ANEMIA; METAANALYSIS; IMPACT Multiple languages Medicine, General & Internal Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/23168