Universität zu Köln

Lauterbach, Mario A. R. and Wunderlich, F. Thomas (2017). Macrophage function in obesity-induced inflammation and insulin resistance. Pflugers Arch., 469 (3-4). S. 385 - 397. NEW YORK: SPRINGER. ISSN 1432-2013

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Abstract

The steadily increasing obesity epidemic affects currently 30% of western populations and is causative for numerous disorders. It has been demonstrated that immune cells such as macrophages reside in or infiltrate metabolic organs under obese conditions and cause the so-called low-grade inflammation or metaflammation that impairs insulin action thus leading to the development of insulin resistance. Here, we report on data that specifically address macrophage biology/physiology in obesityinduced inflammation and insulin resistance.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Lauterbach, Mario A. R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Wunderlich, F. Thomas UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-236087
DOI:	10.1007/s00424-017-1955-5
Journal or Publication Title:	Pflugers Arch.
Volume:	469
Number:	3-4
Page Range:	S. 385 - 397
Date:	2017
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-2013
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language NECROSIS-FACTOR-ALPHA; NF-KAPPA-B; ALTERNATIVELY ACTIVATED MACROPHAGES; ADIPOSE-TISSUE INFLAMMATION; DIET-INDUCED OBESITY; INNATE IMMUNE CELLS; WEIGHT-LOSS; TNF-ALPHA; PROINFLAMMATORY PHENOTYPE; MEDIATED INFLAMMATION Multiple languages Physiology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/23608