Universität zu Köln

Meyer, M. F., Kreppel, M., Meinrath, J., Gruunewald, I, Stenner, M., Drebber, U., Quaas, A., Odenthal, M., Semrau, R., Huebbers, C. U., Zoeller, J., Huettenbrink, K-B, Buettner, R. and Beutner, D. (2017). Prediction of outcome by lymph node ratio in patients with parotid gland cancer. Clin. Otolaryngol., 42 (1). S. 98 - 104. HOBOKEN: WILEY. ISSN 1749-4486

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Abstract

Objective: Lymph node ratio (LNR) has been shown to be an independent predictor of recurrence risk and survival in different entities of carcinoma. Methods: In this retrospective chart review, 128 patients with parotid gland cancer (PGC) subsequently treated by primary surgery were included. About 64% (n = 82) of these patients were additionally treated with adjuvant radiotherapy. Five-year overall survival rates were determined by subgroups based on LNR value. Results: Lymph node ratio was found to be significantly associated with overall survival rate (P < 0.001). Using univariate analyses, pathological tumour-node-metastasis (TNM)-stage, UICC-stage grouping and extracapsular spread were found to be significant predictors of overall survival (P < 0.001). However, with a multivariate analyses, LNR remained the only independent predictor of overall survival (P = 0.043). Conclusions: After surgery for PGC, evaluation of the neck using LNR was found to reliably stratify the overall survival rate.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Meyer, M. F. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kreppel, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Meinrath, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Gruunewald, I UNSPECIFIED UNSPECIFIED UNSPECIFIED Stenner, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Drebber, U. UNSPECIFIED UNSPECIFIED UNSPECIFIED Quaas, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Odenthal, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Semrau, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Huebbers, C. U. UNSPECIFIED UNSPECIFIED UNSPECIFIED Zoeller, J. UNSPECIFIED UNSPECIFIED UNSPECIFIED Huettenbrink, K-B UNSPECIFIED UNSPECIFIED UNSPECIFIED Buettner, R. UNSPECIFIED UNSPECIFIED UNSPECIFIED Beutner, D. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-240345
DOI:	10.1111/coa.12672
Journal or Publication Title:	Clin. Otolaryngol.
Volume:	42
Number:	1
Page Range:	S. 98 - 104
Date:	2017
Publisher:	WILEY
Place of Publication:	HOBOKEN
ISSN:	1749-4486
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ORAL-CAVITY CANCER; PROGNOSTIC-FACTORS; DENMARK 1990-2005; NECK DISSECTION; DANISH HEAD; DENSITY; CARCINOMA; METASTASIS; SURVIVAL; PATTERN Multiple languages Otorhinolaryngology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/24034