Mallmann, Michael R., Graham, Viola, Roesing, Bettina, Gottschalk, Ingo, Mueller, Andreas, Gembruch, Ulrich ORCID: 0000-0001-8284-4669, Geipel, Annegret and Berg, Christoph (2017). Thoracoamniotic Shunting for Fetal Hydrothorax: Predictors of Intrauterine Course and Postnatal Outcome. Fetal Diagn. Ther., 41 (1). S. 58 - 66. BASEL: KARGER. ISSN 1421-9964

Full text not available from this repository.

Abstract

Objective: To assess predictors for survival and complications among a relatively large cohort of fetuses with hydro thorax treated by thoracoamniotic shunting. Methods: All cases with hydrothorax treated by thoracoamniotic shunting in a 10-year period (2002-2011) in two centers were retrospectively reviewed. Results: A total of 78 fetuses with hydrothorax treated with thoracoamniotic shunting were included in the study. Mean gestational age at diagnosis was 25.6 weeks (12-34 weeks). Initial thoracoamniotic shunting was performed at a mean gestational age of 26.5 weeks (16-33 weeks). A mean of 2.53 shunts (1-7) were inserted per fetus. Of the 78 fetuses, 9 (11.5%) died in utero, 69 (88.5%) were born alive and 46 (59%) survived. Prognostic markers significantly associated with nonsurvival were polyhydramnios, hydrops placentae and mediastinal shift at initial scan, onset of hydrops after first shunt placement, rupture of membranes, a shunt-birth interval <4 weeks and low gestational age at birth. In our cohort, fetuses with trisomy 21 had a significantly better survival than euploid fetuses. Conclusions: Although associated with a significant rate of repeated interventions, thoracoamniotic shunting in fetuses with severe hydrothorax results in an overall survival rate of 59%. Fetuses with hydrothorax and trisomy 21 have a better survival when compared to euploid fetuses. (C) 2016 S. Karger AG, Basel

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Mallmann, Michael R.UNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Graham, ViolaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Roesing, BettinaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gottschalk, IngoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Mueller, AndreasUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Gembruch, UlrichUNSPECIFIEDorcid.org/0000-0001-8284-4669UNSPECIFIED
Geipel, AnnegretUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Berg, ChristophUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-243390
DOI: 10.1159/000446110
Journal or Publication Title: Fetal Diagn. Ther.
Volume: 41
Number: 1
Page Range: S. 58 - 66
Date: 2017
Publisher: KARGER
Place of Publication: BASEL
ISSN: 1421-9964
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
PLEURAL EFFUSION; CHYLOTHORAX; PLEURODESIS; MANAGEMENT; INSERTION; THERAPY; OK-432Multiple languages
Obstetrics & GynecologyMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/24339

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item