Universität zu Köln

Dietlein, Markus and Drzezga, Alexander (2017). Taste Disorder (Dysgeusia) and Radioiodine Therapy of the Thyroid Carcinoma Precautions by Antidepressants and Sedative observed. Nuklearmedizin, 56 (4). S. 125 - 132. STUTTGART: SCHATTAUER GMBH-VERLAG MEDIZIN NATURWISSENSCHAFTEN. ISSN 0029-5566

Full text not available from this repository.

Abstract

In addition to xerostomia, taste dysfunction (hypo-, dysgeusia) is an independent side effect of radioiodine therapy of thyroid cancer. Hypogeusia results from damage of the small mucous salivary glands in the vicinity of the taste buds. Particularly in those patients, who are treated with drugs such as antidepressants or sedatives, taste dysfunction becomes frequently clinically symptomatic. If feasible, therapy regimens bearing a potential risk for taste dysfunction should be switched. Additional damage to taste function should be minimalized, including cessation of smoking, change of agents for dental hygiene, and change of toothpaste. If the medical indication for ablative radioiodine therapy is based on the patient's decision, the patient should be informed about alternative strategies. Potential clinical consequences of the sialadenitis (xerostomia, alteration in taste, risk of caries and tooth extraction, lacrimal gland dysfunction, tearing and need of dacryocystorhinostomy) should be revealed completely. Adapted to the initial risk of relapse, the I-131-activity for ablation should be reduced to the latest standard of care. Clinical data are currently too heterogeneous to decide whether rhTSH might reduce the rate of dysgeusia. The specialist in nuclear medicine should be aware of the multifactorial causes of taste dysfunction, in particular if the patient seeks medical advice after radioiodine therapy.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Dietlein, Markus UNSPECIFIED UNSPECIFIED UNSPECIFIED Drzezga, Alexander UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-245722
DOI:	10.3413/Nukmed-0906-17-06
Journal or Publication Title:	Nuklearmedizin
Volume:	56
Number:	4
Page Range:	S. 125 - 132
Date:	2017
Publisher:	SCHATTAUER GMBH-VERLAG MEDIZIN NATURWISSENSCHAFTEN
Place of Publication:	STUTTGART
ISSN:	0029-5566
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CANCER; SALIVARY; SURVIVAL; ABLATION; HORMONE; IODINE Multiple languages Radiology, Nuclear Medicine & Medical Imaging Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/24572