Koeberlein-Neu, Juliane ORCID: 0000-0002-3451-7847, Mennemann, Hugo, Hamacher, Stefanie ORCID: 0000-0003-2158-9101, Waltering, Isabel, Jaehde, Ulrich, Schaffert, Corinna and Rose, Olaf (2016). Interprofessional Medication Management in Patients With Multiple Morbidities A Cluster-randomized Trial (the WestGem Study). Dtsch. Arztebl. Int., 113 (44). S. 741 - 757. COLOGNE: DEUTSCHER AERZTE-VERLAG GMBH. ISSN 1866-0452

Full text not available from this repository.

Abstract

Background: Medication reviews and medication management are being used more and more around the world to improve medication safety. Both of these tools were originally conceived as pharmaceutical care activities and have recently been developed into interdisciplinary approaches. We studied the efficacy of interprofessional medication management for multimorbid patients that takes their medical conditions, but also their general living situation into account. Methods: A comprehensive medication management was performed, which involved the collection of information on the drugs each patient took, the way they were stored, the patient's drug intake and handling, and any problems that arose with pharmacotherapy. The interventional approach was evaluated over a period of 15 months in a cluster-randomized controlled trial with a stepped wedge design. The primary endpoint was the quality of pharmacotherapy, as assessed with the Medication Appropriateness Index (MAI). A mixed model was used to analyze efficacy. Results: 162 patients were enrolled in the study; 142 were included in the intention-to-treat analysis (53.3% women, mean age 76.8 +/- 6.3 years). The mean total MAI score decreased significantly (p <= 0.001) from the control phase (29.21, 95% CI [26.09; 32.33]) to the intervention phase (22.27 [19.00; 25.54]), with an effect strength (Cohen's d) of -0.24 [-0.36; -0.13]. The number of drug-related problems declined as well. Conclusion: In this study, interprofessional collaboration increased medication safety. Working across disciplinary boundaries allowed for a decrease in drug-related problems and brought up aspects outside the purview of the primary care physician.

Item Type: Journal Article
Creators:
CreatorsEmailORCIDORCID Put Code
Koeberlein-Neu, JulianeUNSPECIFIEDorcid.org/0000-0002-3451-7847UNSPECIFIED
Mennemann, HugoUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Hamacher, StefanieUNSPECIFIEDorcid.org/0000-0003-2158-9101UNSPECIFIED
Waltering, IsabelUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Jaehde, UlrichUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Schaffert, CorinnaUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
Rose, OlafUNSPECIFIEDUNSPECIFIEDUNSPECIFIED
URN: urn:nbn:de:hbz:38-255858
DOI: 10.3238/arztebl.2016.0741
Journal or Publication Title: Dtsch. Arztebl. Int.
Volume: 113
Number: 44
Page Range: S. 741 - 757
Date: 2016
Publisher: DEUTSCHER AERZTE-VERLAG GMBH
Place of Publication: COLOGNE
ISSN: 1866-0452
Language: English
Faculty: Unspecified
Divisions: Unspecified
Subjects: no entry
Uncontrolled Keywords:
KeywordsLanguage
THERAPY MANAGEMENT; COMMUNITY PHARMACISTS; APPROPRIATENESS INDEX; CARE; INTERVENTIONS; ILLNESS; ISSUESMultiple languages
Medicine, General & InternalMultiple languages
Refereed: Yes
URI: http://kups.ub.uni-koeln.de/id/eprint/25585

Downloads

Downloads per month over past year

Altmetric

Export

Actions (login required)

View Item View Item