Universität zu Köln

Seeliger, Ingo, Frerichs, Anneke, Glowa, Dorothea, Velo, Laura, Comelli, Petra, Chandler, John W. and Werr, Wolfgang (2016). The AP2-type transcription factors DORNRA-SCHEN and DORNRA-SCHEN-LIKE promote G1/S transition. Mol. Genet. Genomics, 291 (5). S. 1835 - 1850. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 1617-4623

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Abstract

The paralogous genes DORNRA-SCHEN (DRN) and DORNRA-SCHEN-LIKE (DRNL) encode AP2-type transcription factors that are expressed and act cell-autonomously in the central stem-cell zone or lateral organ founder cells (LOFCs) in the peripheral zone of the Arabidopsis shoot meristem (SAM), but their molecular contribution is unknown. Here, we show using the Arabidopsis thaliana MERISTEM LAYER 1 promoter that DRN and DRNL share a common function in cell cycle progression and potentially provide local competence for G1-S transitions in the SAM. Analysis of double transgenic DRN::erGFP and DRNL::erCERULEAN promoter fusion lines suggests that the trajectory of this cellular competence starts with DRN activity in the central stem-cell zone and extends locally via DRNL activity into groups of founder cells at the IM or FM periphery. Our data support the scenario that after gene duplication, DRN and DRNL acquired different transcription domains within the shoot meristem, but retained protein function that affects cell cycle progression, either centrally in stem cells or peripherally in primordial founder cells, a finding that is of general relevance for meristem function.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Seeliger, Ingo UNSPECIFIED UNSPECIFIED UNSPECIFIED Frerichs, Anneke UNSPECIFIED UNSPECIFIED UNSPECIFIED Glowa, Dorothea UNSPECIFIED UNSPECIFIED UNSPECIFIED Velo, Laura UNSPECIFIED UNSPECIFIED UNSPECIFIED Comelli, Petra UNSPECIFIED UNSPECIFIED UNSPECIFIED Chandler, John W. UNSPECIFIED UNSPECIFIED UNSPECIFIED Werr, Wolfgang UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-261203
DOI:	10.1007/s00438-016-1224-x
Journal or Publication Title:	Mol. Genet. Genomics
Volume:	291
Number:	5
Page Range:	S. 1835 - 1850
Date:	2016
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	1617-4623
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language VITRO SHOOT REGENERATION; ARABIDOPSIS-THALIANA; CELL-CYCLE; AUXIN BIOSYNTHESIS; ORGAN DEVELOPMENT; HYPOCOTYL GROWTH; DORNROSCHEN-LIKE; GCC BOX; GENE; EXPRESSION Multiple languages Biochemistry & Molecular Biology; Genetics & Heredity Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/26120