Weingaertner, V., Dargatz, N., Weber, C., Mueller, D., Stock, S., Voltz, R. and Gaertner, J. (2016). Patient reported outcomes in randomized controlled cancer trials in advanced disease: a structured literature review. Expert Rev. Clin. Pharmacol., 9 (6). S. 821 - 830. ABINGDON: TAYLOR & FRANCIS LTD. ISSN 1751-2441
Full text not available from this repository.Abstract
Introduction: In advanced cancer quality of life (QoL) is the most important goal of care. It is measured by patient-reported-outcomes (PRO). This structured review evaluated how randomized controlled trials (RCTs) on anti-cancer therapy in advanced cancer reported PRO.Methods: Search was performed in MEDLINE via PubMed for RCTs with median patient survival of 2years. Reporting was rated with the Consolidated Standards of Reporting Trials (CONSORT) PRO extension.Results: Of 370 retrieved publications, 117 were eligible, but only 30/117 (26%) reported PRO. QoL was most frequently measured (29/30). On average, 4.4 (SD 2.5) of the 14 CONSORT items were met.Conclusion: PRO are insufficiently reported in advanced cancer trials. Yet, this is paramount to enable an informed and patient-oriented decision making process.
| Item Type: | Journal Article | ||||||||||||||||||||||||||||||||
| Creators: |
|
||||||||||||||||||||||||||||||||
| URN: | urn:nbn:de:hbz:38-273832 | ||||||||||||||||||||||||||||||||
| DOI: | 10.1586/17512433.2016.1164595 | ||||||||||||||||||||||||||||||||
| Journal or Publication Title: | Expert Rev. Clin. Pharmacol. | ||||||||||||||||||||||||||||||||
| Volume: | 9 | ||||||||||||||||||||||||||||||||
| Number: | 6 | ||||||||||||||||||||||||||||||||
| Page Range: | S. 821 - 830 | ||||||||||||||||||||||||||||||||
| Date: | 2016 | ||||||||||||||||||||||||||||||||
| Publisher: | TAYLOR & FRANCIS LTD | ||||||||||||||||||||||||||||||||
| Place of Publication: | ABINGDON | ||||||||||||||||||||||||||||||||
| ISSN: | 1751-2441 | ||||||||||||||||||||||||||||||||
| Language: | English | ||||||||||||||||||||||||||||||||
| Faculty: | Unspecified | ||||||||||||||||||||||||||||||||
| Divisions: | Unspecified | ||||||||||||||||||||||||||||||||
| Subjects: | no entry | ||||||||||||||||||||||||||||||||
| Uncontrolled Keywords: |
|
||||||||||||||||||||||||||||||||
| Refereed: | Yes | ||||||||||||||||||||||||||||||||
| URI: | http://kups.ub.uni-koeln.de/id/eprint/27383 |
Downloads
Downloads per month over past year
Altmetric
Export
Actions (login required)
 |
View Item |