Universität zu Köln

Schubach, Nicola Elisabeth, Mehler, Katrin, Roth, Bernhard, Korsch, Eckhard, Laux, Rainhard, Singer, Dominique, von der Wense, Axel, Treszl, Andras and Huenseler, Christoph (2016). Skin conductance in neonates suffering from abstinence syndrome and unexposed newborns. Eur. J. Pediatr., 175 (6). S. 859 - 869. NEW YORK: SPRINGER. ISSN 1432-1076

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Abstract

The aims of this study were to compare the skin conductance (SC) of newborns with opiate-induced neonatal abstinence syndrome (NAS) to that of unexposed newborns and to evaluate the potential of SC readings to detect distress in the context of NAS objectively. The SC of 12 newborns with NAS and 12 unexposed newborns was measured at nine specific times during their first 6 weeks of life. The number of SC fluctuations per second (NSCF/s), the amplitude of SC fluctuation, and the mean level of SC were recorded and analyzed. The SC of newborns treated for symptoms of NAS differed significantly from the SC of unexposed newborns with regard to the NSCF/s (p = 0.04). With the mean level of SC, we observed an interaction between groups over time (p value for interaction = 0.02). With increasing postnatal age, we observed higher values in all three SC parameters. Conclusion: The NSCF/s and the mean level of SC appear to be suitable to reflect the distress of newborns suffering from NAS. As it is known that the sensitivity of SC increases with the level of stress experienced, its potential to indicate elevated stress levels in infants with NAS should be investigated in future studies evaluating different therapy regimens.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Schubach, Nicola Elisabeth UNSPECIFIED UNSPECIFIED UNSPECIFIED Mehler, Katrin UNSPECIFIED UNSPECIFIED UNSPECIFIED Roth, Bernhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Korsch, Eckhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Laux, Rainhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Singer, Dominique UNSPECIFIED UNSPECIFIED UNSPECIFIED von der Wense, Axel UNSPECIFIED UNSPECIFIED UNSPECIFIED Treszl, Andras UNSPECIFIED UNSPECIFIED UNSPECIFIED Huenseler, Christoph UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-274027
DOI:	10.1007/s00431-016-2716-8
Journal or Publication Title:	Eur. J. Pediatr.
Volume:	175
Number:	6
Page Range:	S. 859 - 869
Date:	2016
Publisher:	SPRINGER
Place of Publication:	NEW YORK
ISSN:	1432-1076
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language OPIATE WITHDRAWAL; PAIN ASSESSMENT; INFANTS BORN; MANAGEMENT; STRESS; RESPONSES; METHADONE; SCALE Multiple languages Pediatrics Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/27402