Universität zu Köln

Ferris, Maria, Gibson, Keisha, Plattner, Brett, Gipson, Debbie S., Kotanko, Peter ORCID: 0000-0003-4373-412X, Marcelli, Daniele ORCID: 0000-0002-7650-8578, Marelli, Cristina, Etter, Michael, Carioni, Paola, von Gersdorff, Gero, Xu, Xiaoqi, Kooman, Jeroen P., Xiao, Qingqing, van der Sande, Frank M., Power, Albert ORCID: 0000-0003-2283-5431, Picoits-Filho, Roberto, Sylvestre, Lucimary, Westreich, Katherine and Usvyat, Len ORCID: 0000-0003-2745-1429 (2016). Hemodialysis outcomes in a global sample of children and young adult hemodialysis patients: the PICCOLO MONDO cohort. Clin. Kidney J., 9 (2). S. 295 - 303. OXFORD: OXFORD UNIV PRESS. ISSN 2048-8513

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Abstract

Background: The aim of this study was to describe the experience of pediatric and young adult hemodialysis (HD) patients from a global cohort. Methods: The Pediatric Investigation and Close Collaborative Consortium for Ongoing Life Outcomes for MONitoring Dialysis Outcomes (PICCOLO MONDO) study provided de-identified electronic information of 3244 patients, ages 0-30 years from 2000 to 2012 in four regions: Asia, Europe, North America and South America. The study sample was categorized into pediatric (<= 18 years old) and young adult (19-30 years old) groups based on the age at dialysis initiation. Results: For those with known end-stage renal disease etiology, glomerular disease was the most common diagnosis in children and young adults. Using Europe as a reference group, North America [ odds ratio (OR) 2.69; CI 1.29, 5.63] and South America (OR 4.21; CI 2.32, 7.63) had the greatest mortality among young adults. North America also had higher rates of overweight, obesity, hypertension, cardiovascular disease, hospitalizations and secondary diabetes compared with all other regions. Initial catheter use was greater for North American (86.4% in pediatric patients and 75.2% in young adults) and South America (80.6% in pediatric patients and 75.9% in young adults). Catheter use at 1-year follow-up was most common in North American children (77.3%) and young adults (62.9%). Asia had the lowest rate of catheter use. For both age groups, dialysis adequacy (equilibrated Kt/V) ranged between 1.4 and 1.5. In Asia, patients in both age groups had significantly longer treatment times than in any other region. Conclusions: The PICCOLO MONDO study has provided unique baseline and 1-year follow-up information on children and young adults receiving HD around the globe. This cohort has brought to light aspects of care in these age groups that warrant further investigation.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Ferris, Maria UNSPECIFIED UNSPECIFIED UNSPECIFIED Gibson, Keisha UNSPECIFIED UNSPECIFIED UNSPECIFIED Plattner, Brett UNSPECIFIED UNSPECIFIED UNSPECIFIED Gipson, Debbie S. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kotanko, Peter UNSPECIFIED orcid.org/0000-0003-4373-412X UNSPECIFIED Marcelli, Daniele UNSPECIFIED orcid.org/0000-0002-7650-8578 UNSPECIFIED Marelli, Cristina UNSPECIFIED UNSPECIFIED UNSPECIFIED Etter, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Carioni, Paola UNSPECIFIED UNSPECIFIED UNSPECIFIED von Gersdorff, Gero UNSPECIFIED UNSPECIFIED UNSPECIFIED Xu, Xiaoqi UNSPECIFIED UNSPECIFIED UNSPECIFIED Kooman, Jeroen P. UNSPECIFIED UNSPECIFIED UNSPECIFIED Xiao, Qingqing UNSPECIFIED UNSPECIFIED UNSPECIFIED van der Sande, Frank M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Power, Albert UNSPECIFIED orcid.org/0000-0003-2283-5431 UNSPECIFIED Picoits-Filho, Roberto UNSPECIFIED UNSPECIFIED UNSPECIFIED Sylvestre, Lucimary UNSPECIFIED UNSPECIFIED UNSPECIFIED Westreich, Katherine UNSPECIFIED UNSPECIFIED UNSPECIFIED Usvyat, Len UNSPECIFIED orcid.org/0000-0003-2745-1429 UNSPECIFIED
URN:	urn:nbn:de:hbz:38-278989
DOI:	10.1093/ckj/sfv157
Journal or Publication Title:	Clin. Kidney J.
Volume:	9
Number:	2
Page Range:	S. 295 - 303
Date:	2016
Publisher:	OXFORD UNIV PRESS
Place of Publication:	OXFORD
ISSN:	2048-8513
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language MONITORING DIALYSIS OUTCOMES; CHRONIC KIDNEY-DISEASE; PEDIATRIC EXPERIENCE; CONSUMPTION; PATTERNS; OBESITY Multiple languages Urology & Nephrology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/27898