Universität zu Köln

Korsch, Eckhard, Weiss, Michael, Pieper, Monika, Schildgen, Verena, Schildgen, Oliver ORCID: 0000-0003-4297-9627 and Brockmann, Michael (2016). A case of suspected Escherichia coli-associated meningitis accompanied by human bocavirus detection in the cerebrospinal fluid of a 13-day-old newborn. Rev. Med. Microbiol., 27 (2). S. 72 - 75. PHILADELPHIA: LIPPINCOTT WILLIAMS & WILKINS. ISSN 1473-5601

Full text not available from this repository.

Abstract

Introduction: The human bocavirus (HBoV) type 1 is associated with respiratory infections and causes mild-to-severe disease in all age groups. The virus is also associated with infections in other sites, such as the nervous system, but little is known about the disease process. As an animal model is not available to study HBoV pathogenesis, clinical case reports, cohort studies, and cell culture data remain the major sources of information about the virus. Case presentation: This article reports a clinical case of suspected meningitis associated with HBoV-DNA detection in cerebrospinal fluid and nasopharyngeal wash, accompanied by Escherichia coli infection in a 13-day-old male patient. Conclusion: Although an etiological role of HBoV cannot be proven in this clinical case, the observations made confirm those from earlier studies. There appear to be a small number of cases in which HBoV - actively or passively - is able to pass the blood-brain barrier and contribute to clinical disease. Taking into account that there are a large number of neurological cases in which no pathogen can be detected, we suggest that detection of HBoV be included in routine cerebrospinal fluid screening protocols, particularly multiplex diagnostic assays. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Korsch, Eckhard UNSPECIFIED UNSPECIFIED UNSPECIFIED Weiss, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED Pieper, Monika UNSPECIFIED UNSPECIFIED UNSPECIFIED Schildgen, Verena UNSPECIFIED UNSPECIFIED UNSPECIFIED Schildgen, Oliver UNSPECIFIED orcid.org/0000-0003-4297-9627 UNSPECIFIED Brockmann, Michael UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-279007
DOI:	10.1097/MRM.0000000000000070
Journal or Publication Title:	Rev. Med. Microbiol.
Volume:	27
Number:	2
Page Range:	S. 72 - 75
Date:	2016
Publisher:	LIPPINCOTT WILLIAMS & WILKINS
Place of Publication:	PHILADELPHIA
ISSN:	1473-5601
Language:	English
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language ENCEPHALITIS; CHILDREN; PERSISTENCE; PARVOVIRUS Multiple languages Microbiology Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/27900