Universität zu Köln

Suarez, I., Boell, B., Shimabukuro-Vornhagen, A., Michels, G., von Bergwelt-Baildon, M. and Kochanek, M. (2016). Mortality of hematology-oncology patients with neutropenia in intensivecare. Med. Klin.-Intensivmed Notfallmed., 111 (2). S. 84 - 92. HEIDELBERG: SPRINGER HEIDELBERG. ISSN 2193-6226

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Abstract

Febrile neutropenia remains one of the most common reasons for hospital admission of patients with underlying oncologic disease. These patients have an up to 10-fold increased risk of developing sepsis, which often leads to these patients being transferred to the intensive care unit (ICU). The survival of neutropenic patients with sepsis in particular has improved in recent years, due to advanced therapy in intensive care (surviving sepsis campaign); however few large international studies of neutropenic cancer patients in the ICU are available. In a retrospective study, 59 episodes of neutropenic cancer patients in the internal medicine ICU at the University Hospital of Cologne over a period of 2 years were analyzed. Pneumonia with or without sepsis are the main admission diagnoses of neutropenic cancer patients in the ICU. The mortality rate of these patients is very high (50.8 %). Pneumonia and sepsis, stem cell transplantation, mechanical ventilation, and acute renal failure with or without dialysis are correlated with mortality. Cancer patients should be admitted immediately to the ICU if they have signs of sepsis for early monitoring and treatment. Neutropenic patients have an increased risk for infectious complications and a risk for sepsis with higher mortality rates.

Item Type:	Journal Article
Creators:	Creators Email ORCID ORCID Put Code Suarez, I. UNSPECIFIED UNSPECIFIED UNSPECIFIED Boell, B. UNSPECIFIED UNSPECIFIED UNSPECIFIED Shimabukuro-Vornhagen, A. UNSPECIFIED UNSPECIFIED UNSPECIFIED Michels, G. UNSPECIFIED UNSPECIFIED UNSPECIFIED von Bergwelt-Baildon, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED Kochanek, M. UNSPECIFIED UNSPECIFIED UNSPECIFIED
URN:	urn:nbn:de:hbz:38-283027
DOI:	10.1007/s00063-015-0039-6
Journal or Publication Title:	Med. Klin.-Intensivmed Notfallmed.
Volume:	111
Number:	2
Page Range:	S. 84 - 92
Date:	2016
Publisher:	SPRINGER HEIDELBERG
Place of Publication:	HEIDELBERG
ISSN:	2193-6226
Language:	German
Faculty:	Unspecified
Divisions:	Unspecified
Subjects:	no entry
Uncontrolled Keywords:	Keywords Language CRITICALLY-ILL PATIENTS; CARE-UNIT; SURVIVAL; MALIGNANCIES; MANAGEMENT; SEPSIS; ICU Multiple languages Medicine, General & Internal Multiple languages
Refereed:	Yes
URI:	http://kups.ub.uni-koeln.de/id/eprint/28302